Not exact matches
Representative photomicrographs of
lung tissue from unvaccinated unchallenged
mice (normal) and from Balb /
c mice two days after challenge with SARS - CoV that had previously been given PBS only (no vaccine) or live virus.
Structural
lung damage caused by induced asthma mimics the phenotype found in asthma patients more closely than does the induced damage in BALB /
c mice.
Representative photomicrographs of
lung tissue two days after challenge of Balb /
c mice with SARS - CoV that had previously been given a SARS - CoV vaccine.
Mean
lung cellular infiltration / lesion pathology and percent eosinophils in infiltrates for each vaccine dosage group for each
mouse strain (Balb /
c or
C57BL / 6) two days after challenge with SARS - CoV.
Representative photomicrographs of
lung tissue two days after challenge of Balb /
c and
C57BL / 6
mice that had previously been given a SARS - CoV vaccine.
All
mice exhibited histopathologic changes in
lungs two days after challenge including all animals vaccinated (Balb /
C and
C57BL / 6) or given live virus, influenza vaccine, or PBS suggesting infection occurred in all.
(A) Genotype documentation of - / y hemizygous males and - / - homozygous females; evidence of Slc6a14 deletion in colon and
lung tissues from - / y hemizygous males and - / - homozygous females; expression of Slc6a14 in colon (
C) and
lung (L) but not in mammary gland (M) in wild - type (WT) female
mice.
(
C) In vivo inhibition of
lung inflammation in an ovalbumin - induced asthma model in
mice.
(
C) In a separate group of
mice, bacterial CFUs were quantified in
lung homogenates (N = 10
mice per group).