Sentences with phrase «cdna library screening»

The team plans to accomplish this goal by expanding whole genome or exome sequencing for patients, using patient - derived cells to discover new disease mechanisms, and personalized drug library screening.

Last, the Novartis RIPK2 inhibitor was obtained in a similar manner to GSK583 and was based on a proprietary chemical library screen.

The higher production efficiencies gained by ALiCE ™ will make it possible for biopharmaceutical researchers to detect a significantly higher number of candidates from each DNA library screened, eventually leading to a higher number of viable candidates for development.

We then retested the nine hits from the NINDS library screening in 96 - well plates.

I found the music library screens for USB drives and iOS devices easy to navigate, but UConnect does not yet include an advanced Bluetooth streaming connection that allows music selection from its touchscreen.

The music library screen, however, is horrible, requiring too many clicks to choose and play an album or artist.

While USB port, SD card slot, and hard drive sources let you see a music library screen, the Bluetooth streaming only shows track information, along with skip and pause controls.

BMW has never quite got the music library screen right, making it difficult to select and start playback of stored media.

The music library screen shows up for drives and iOS devices plugged into the Forester's USB port.

I liked the new music library screens, which included an option for choosing albums by cover art.

The music library screen shows fields for artist, genre, and album, all of which are actually filters.

1) Bootup 2) Showcase more of the drawing app 3) demonstrate edge to edge writing functionality 4) give you a sense of our new library screen 5) show you the pre-loaded apps we have on the unit such as ES FILE Explorer, Moon + Reader and EZPDF Reader 6) fire up said apps and show off reading 7) show you the stock PDF Reader and EPUB / MOBI Reader

The library screen can display your books in gridded or list view and you can filter by author, title or date.

This is simply not the case, it only appears on your library screen.

The third button is a short, vertical silvery bar for returning to the preceding task: If you're reading a book, for example, pressing that button moves you to the library screen where you selected the book.

From the library screen you can search for books by recently read, author, title, series or tag — or browse the file tree.

Drag and drop your Mobi e-books into its library screen, highlight them all and select «Batch Convert» from the right - click menu.

On the library screen you'll see the book's cover, the book's title and the author's name.

This will launch the Overdrive app and take you to the library screen where you must click download and are taken to a download queue where you select your file and click download again.

The library screen is organized into categories such as books, magazines, movies & TV, apps, kids, catalogs, and newspapers.

In keeping with that kid - friendly theme, there's a special kids section on the main library screen.

Not exact matches

The Meatpacking District clubhouse is home to a 24 - room hotel and has a screening room, library, spa, and dining room.

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December 23: Take in a showing of The Polar Express on the library's big screen with surround sound (Waltham)

The 100 % kid - perfect tablet with large, hi - res screen, Wi - Fi with kid - safe web and access to the LeapFrog educator - approved library.

Whether it is sharing our eBooks or audiobooks together or watching TV shows and movies, hoopla offers a range of family content and an experience that can be enjoyed across screens — all with a library card.»

At 11 a.m., NYC Administration for Children's Services Commissioner David Hansell announces a new partnership with NYU College of Dentistry to provide dental screenings to children in foster care, Nicholas Scoppetta Children's Center, fourth floor library, 492 First Ave., Manhattan.

Mr. Jackson (also known as Sekou Molefi Baako) is an East Elmhurst resident with a long history of community service, including 36 years as Executive Director of the Queens Library's Langston Hughes Community Library and Cultural Center, a full - service, general circulation library with an extensive reference collection of materials related to African American history and culture, and a cultural arts program that offers a variety of programming of independent film video screenings, stage presentations, panel discussions, concerts, art exhibitions and more.

The 17,000 - square - foot library now has an airier design, with new furniture, elevators and wheelchair lifts, plus more than 60 new computers and two large touch - screen monitors.

«If we can pick up certain design features from the screens, it can guide us to design larger combinatorial libraries based on these leads,» Yanik says.

David Sinclair of Harvard Medical School in Boston and colleagues at the biotech firm BIOMOL Research Laboratories in Plymouth Meeting, Pennsylvania, screened a library of compounds for molecules that trigger SIRT1 activity.

«The lipidoid material screen is just an example demonstrated in this article; a similar strategy can be readily extended to other libraries or other organ systems,» Peng adds.

«The next step for us is to utilize these computer models to screen a virtual library of hundreds of thousands of new amines, and identify some new amine candidates predicted to have way better carbon absorption properties.

«The next step is screening the Takeda libraries to find a similar drug that doesn't affect the human proteasome.

In this study, the researchers screened a library of 200,000 small molecule compounds to identify potential inhibitors of Ebola virus RNA synthesis.

In 1998, for example, Wiman's team screened a library of 2000 compounds from the U.S. National Cancer Institute and found two that appeared to restore mutant p53's ability to kill cancer cells.

To find new compounds for spraying and nets, IVCC has partnered with several large chemical companies including BASF, Syngenta, and Sumitomo to screen more than 4 million compounds in their libraries.

This work began as part of a biodefense grant from the National Institutes of Health, screening a library of 30,000 compounds for activity against the envelope of Nipah virus, an emerging infection first identified in 1999 in Malaysia.

When researchers screened a library of more than 200 drugs and related compounds for activity against embryonal subtype tumor cells from three patients, the most promising results involved drugs that increased oxidative stress in tumor cells.

Today, the pharmaceutical industry screens synthetic chemical libraries of thousands of molecules to find one that may have a medicinal effect, said Parekkadan, who joined Rutgers» School of Engineering in January.

They can now take a genome sequence (or many of them) and make a protein library for screening with unprecedented speed, cost - effectiveness and precision, allowing rapid discovery of potentially beneficial biomolecules from a genome.

For instance, it may soon be possible to automatically separate all of the chemicals in an organism, identify them, and catalogue them in a library for future screening.

Using a robotics - based screening approach, researchers screened a library of 1,192 FDA - approved drugs for any that suppressed tumors in the fly and identified several that improved overall survival.

Companies in the partnership supply compound libraries and drug discovery expertise to the effort, while academic partners contribute knowledge about the disease and facilities for screens and assays.

The research team plucked seven MERS - specific neutralizing antibodies from the library after using samples of the virus to screen for them.

The researchers created a large library of MphR protein variants and screened them for the ability to switch on production of a fluorescent green protein when they were in the presence of a desired macrolide.

I first used computers to screen through a library of almost half a million compounds and reduce that to a top 237.

As part of drug discovery, one of the earlier stages is you take a huge library of chemical compounds and you screen them with an assay for malaria or TB and you see if that chemical compound kills the parasite or bacteria.

«It will allow us to screen libraries of drug compounds relatively quickly.

Specifically, the research team used a miniaturized, high - speed technology to screen through sample libraries of 2,816 compounds already approved by the US Food and Drug Administration for other uses.