Sentences with phrase «cadherin adhesion»

11) Korswagen, R., Herman, M. and Clevers, H. Separate beta - catenins mediate Wnt signaling and cadherin adhesion in C. elegans.

Association of an A-kinase-anchoring protein signaling scaffold with cadherin adhesion molecules in neurons and epithelial cells.

Not exact matches

The groundbreaking study identified a protein, known as cadherin - 22, as a potential factor in cancer metastasis, or spread, and showed that hindering it decreased the adhesion and invasion rate of breast and brain cancer cells by up to 90 per cent.

As a doctoral student in the lab of Drs. Margaret Wheelock and Keith Johnson at the University of Toledo, Dr. Islam focused on identifying a link between cadherins (a family of cell adhesion proteins) and tumorigenesis (start of cancer cell formation).

Dr. Islam's discovery was published [S. Islam, T. E. Carey, G. T. Wolf, M. J. Wheelock, and K. J. Johnson, «Expression of N - Cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell - cell adhesion,» J. Cell Biol.

Researchers at the Mechanobiology Institute have comprehensively described the network of proteins involved in cell - cell adhesions, or the cadherin interactome.

Despite their importance in cell - cell adhesion, scientists have yet to fully understand how the cadherin - catenin - actin complex forms and is regulated.

Up - regulated expression of zonula occludens protein - 1 in human melanoma associates with N - cadherin and contributes to invasion and adhesion.

N - cadherin - mediated cell — cell adhesion promotes cell migration in a three - dimensional matrix.

An Elmo — Dock complex locally controls Rho GTPases and actin remodeling during cadherin - mediated adhesion.

Cell division orientation is coupled to cell - cell adhesion by the E - cadherin / LGN complex.

Conformational epitopes at cadherin calcium - binding sites and p120 - catenin phosphorylation regulate cell adhesion.

W. E. Reintsch, A. Habring - Mueller, R. W. Wang, A. Schohl, F. Fagotto, beta - Catenin controls cell sorting at the notochord - somite boundary independently of cadherin - mediated adhesion.

The diagnostic domains of two major cell — cell adhesion superfamilies, the cadherins and the immunoglobulins, are present in Monosiga within the extracellular region of putative transmembrane proteins31, 34 (Supplementary Note 8.8).

In their work on compulsive blanket and flank sucking in Dobermanns, the authors identified a single locus with genome - wide significance within the gene Cadherin 2 (cdh2), a widely expressed gene involved in pre - and post-synaptic adhesion.