Sentences with phrase «calcineurin inhibitor»

Abbreviations: AD - MSC: adipose tissue derived mesenchymal stem cells; APC: antigen presenting cell; BM: bone marrow; CNI: calcineurin inhibitor; DC: dendritic cells; GVHD: graft - versus - host disease; HLA: histocompatibility locus antigen; HGF: hepatocyte growth factor; IL: interleukin; IDO: indoleamine 2,3 - dioxygenase; MLR: mixed lymphocyte reaction; MSC: mesenchymal stem cells; PGE2: prostaglandin E2; SC: stem cells; TGF: transforming growth factor; TH: T - helper; T - regs: T - regulatory cells.

In the cohort of patients who received transplants from mismatched unrelated donors, all 43 patients received four doses of abatacept with a calcineurin inhibitor and methotrexate.

For example, CRAC channels in T cells have been clinically validated as important drug targets through human mutations and the use of calcineurin inhibitors that act downstream from CRAC channels.

• Proactive management includes the intermittent, but scheduled use of topical corticosteroids or topical calcineurin inhibitors to areas of the body that frequently have recurrent disease.

Angiotensin II signalling and calcineurin in cardiac fibroblasts: differential effects of calcineurin inhibitors FK506 and cyclosporine A. Therapeutic Advances in Cardiovascular Disease, 6 (1), 5 — 14.

The application of calcineurin inhibitors (CNIs) would abrogate the immunosuppressive effect of MSC therapy.

«Patients using calcineurin inhibitors can potentially experience many adverse effects.

Not exact matches

We also characterized the function of a family of endogenous inhibitors of calcineurin, originally termed MCIP but subsequently renamed as RCAN proteins.