Studies from a group at the University of Glasgow, which are published in the same issue of the journal, show the importance of
calcineurin through different stages of the malaria life - cycle, implicating the protein as a potential target for blocking malaria transmission.
Not exact matches
For example, CRAC channels in T cells have been clinically validated as important drug targets
through human mutations and the use of
calcineurin inhibitors that act downstream from CRAC channels.
Hong - Gang Wang, PhD (D Club) Lois High Bestler Professor of Pediatrics and Pharmacology; Director, Pediatrics Molecular Oncology Program «Ca2 + induced apoptosis
through calcineurin dephosphorylation of BAD» Science, April 1999 860 citations, Web of Science, April 1, 2017