Sentences with phrase «calcium channel»

For example, when a nerve impulse stimulates a muscle fiber to contract, calcium channels in the cell membrane open to allow calcium ions into the muscle cell.

I approached professors, explained that I was willing to work for free, and was soon involved in a molecular biology project concerning N - type calcium channels.

But, for some unknown reason, they come to rely more on calcium channels as they mature.

Since calcium channels are only found in heart and brain tissue, the researchers sought a drug approved to block these pathways.

I arrived at my interviews eager to discuss calcium channels, and how I hoped to do good in the world as a doctor.

Gingival hyperplasia may also be associated with the use of calcium channel blockers (used to treat cardiovascular disease) and phenytoin derivatives (used to control seizures), though these medications are used far less frequently than cyclosporine in veterinary patients.

The team and their collaborators are currently assessing the efficiency of calcium channel blockers to stop the spreading of breast and pancreatic cancer using pre-clinical models and analysing patient data.

We treat these cats with calcium channel blockers such as diltiziam, diuretics such as furosemide and low doses of aspirin.

Excitable cells, such as skeletal muscle and nerve cells, contain voltage - dependent calcium channels in their cell membranes that allow for rapid changes in calcium concentrations.

These medications include beta blockers, ACE inhibitors, calcium channel blocks and diuretics.

(This drug is in a group called calcium channel blockers).

«When we exposed a near - infrared laser beam to these animal models injected with both the nanoparticle and the genetically engineered immune cells, this caused calcium channels on the dendritic cells to open and we saw a corresponding increase in the number of T - cells that were activated,» said Han.

In summary, the authors wrote, «We present a model in which calcium channels play a role in autophagy by regulating the fusion of autophagic vesicles with lysosomes and hence functions in maintaining neuronal homeostasis.»

Among the most interesting ones identified were those associated with 1) the large category of transport, and the more specific categories of carbohydrate transport and cation: amino acid symport; 2) several related to calcium, including calcium ion binding, calmodulin binding, and voltage gated calcium channel activity; 3) DNA damage response and signal transduction; 4) response to oxidative stress; and 5) oxygen and reactive oxygen species metabolism.

«Biochemists uncover structure of cellular memory mechanism: Calcium channel controls thought, movement and metabolism.»

Feske and his colleagues point out that their findings hold critical importance in further evaluation of the effects of new calcium channel inhibitors on immune responses to other chronic infections.

In addition, research has shown that this beneficial compound helps to combat the arterial stiffness that contributes to high blood pressure — while improving endothelial function and helping to modulate calcium channel flow.

In many nerve cells, magnesium serves as Nature's own calcium channel blocker, preventing calcium from rushing into the nerve cell and activating the nerve.

«A docking site per calcium channel cluster: Researchers find link between morphology and function of synapses.»

«Drugs targeting calcium channels have been tested against bipolar disorder with some success, although only in open - label trials and not double - blind clinical trials.

Specifically, they determined that the immune systems in genetically altered mice lacking the critically important calcium channel component STIM1 failed to control TB, leading to severe lung inflammation and premature death.

«Like in all immune modulatory therapies,» Feske adds, «the benefits of incomplete calcium channel inhibition need to be balanced against the dysregulation of the immune response that results when these channels are blocked completely,»

For calcium channels, Yue's and other research groups found that the resemblance element supports an important function, preventing the channel from opening when the cellular calcium level gets high.

The anticonvulsant drugs are thought to control seizures in people by acting on certain neuronal calcium channels.

Immunoglobulin G (IgG) antibodies from patients with the syndrome, applied to bovine adrenal chromaffin cells, reduced the voltage - dependent calcium channel currents by about 40 percent.

Since the cell membrane or the outer covering of the cell is impermeable to Calcium ions, Calcium enters the cell through dedicated calcium channels.

Indeed, in the same paper, the Stanford team reported new discoveries using personalized brain spheroids derived from induced pluripotent stem cells of patients with Timothy syndrome — a rare condition caused by an overactive calcium channel found mainly in the brain and heart.

In the patients» spheroids, interneurons migrated inefficiently but, by adding drugs that blocked the dysfunctional calcium channel, the researchers could reverse the problem.

His laboratory already has shown that by inhibiting calcium channels in T - cells, they were able to prevent T - cell activation in animal models of autoimmune diseases like multiple sclerosis and colitis.

In order to identify the relationship between burst firing and absence seizures, the researchers conducted an experiment to induce absence seizures in mice using gene targeting techniques to delete the T - type calcium channel CaV3.3.

His team's report, which appears in the June 19 issue of the journal Cell, had its genesis in the 1990s with another group's observation that sodium and calcium channels bear a striking resemblance in a small portion of an otherwise very different structure.

After dozens of experiments, the scientists found that a third calcium channel called TRPV4 can transmit both types of itch.

When the IP3R calcium channel receives signals, it creates a pathway for calcium ions to move across cell membranes.

The researchers studied calcium channels in neurons, which allow for the transport of calcium ions from one nerve cell to another, helping the cells transmit itch signals from the skin to other cells in the spinal cord.

Researchers have performed the first human - based study to identify calcium channels in cerebral arteries and determine the distinct role each channel plays in helping control blood flow to the brain.

Ebola virus requires endosomal two - pore calcium channels to enter host cells.

This may be a general mechanism by which diverse calcium channels achieve specific and distinct neuronal responses.

Calcium channels allow the passage of calcium ions in response to depolarization of the cell membrane.

A large observational study found that use of short - acting calcium channel blockers (CCBs) for hypertension is associated with increased incidence of pancreatic cancer among postmenopausal women, when compared with the use of other types of antihypertensive medication and never - use of such agents.

Statins may interact with drugs including calcium channel blockers such as diltiazem and immunosuppressants such as cyclosporine.

(source) BPS has also been found to incite heart arrhythmias in female rats and interfere with calcium channels due to its estrogenic properties.

Maybe calcium channel blockers and beta agonists