Sentences with phrase «calcium signaling»

They are also interested in determining the operating distance of calcium signals in general and would like to answer the question whether the signals can be transmitted to the plant roots.

That is not surprising, because calcium signaling has an impact on nearly every aspect of cellular life.

In general, lithium alters the way calcium signals are sent and received — and the new cell lines will make it possible to study this effect specifically in bipolar disorder - specific cells.

Mark Dell» Acqua, Ph.D., CU School of Medicine: Study the role of calcium signaling in inhibition of synapse formation by beta amyloid plaque in Down syndrome (A-beta is the main component in plaques of Alzheimer's disease patients)

Thrane AS, Thrane VR, Zeppenfeld D, Lou N, Xu Q, Nagelhus EA, Nedergaard M General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex Proc Natl Acad Sci U S A (in press)

Professor Denk found that the starburst amacrine cells generated calcium signals only along those dendrites that were aligned in the same direction as the movement of light.

In contrast, calcium signals dropped slightly when mice were presented a wooden pellet resembling food, but quickly returned when the mice discovered that the wooden pellet was not food.

Now, researchers at NYU Langone Medical Center have identified an important role for calcium signaling in immune responses to chronic infection resulting from Mycobacterium tuberculosis, the bacterium causing tuberculosis (TB).

When brain slices were bathed in a stress hormone, IP3 - induced calcium signaling also increased.

Specifically, the bipolar neurons expressed more genes for membrane receptors and ion channels than non-bipolar cells, particularly those receptors and channels involved in the sending and receiving of calcium signals between cells.

How calcium signals are elicited in different and separate areas of plants is not yet fully understood.

Of general importance for systemic calcium signaling is the wounding of the vascular system of the leaf, which is also responsible for the internal transport of water and nutrients in the plant.

Their new insights are described in a paper titled «Multiple mechanisms drive calcium signal dynamics around laser induced epithelial wounds» published Oct. 3 by the Biophysical Journal.

[Deepak Deshpande et al., «Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction»]

When tested under a microscope, these human astrocytes accomplished calcium signaling at least three times faster than the mouse astrocytes did.

His laboratory also identified the first patients with inherited mutations in ORAI1 and STIM1 genes, showing that they lack calcium signals completely, causing defects in T - cell function and immunodeficiency.

The IZN researchers assume that similar switches based on nuclear calcium signals may have applications in other areas — presumably whenever organisms need to adapt to new conditions over the long term.

Visualization revealed that calcium signals occur systemically and wander from attacked to neighboring leaves within a short period of time, and ultimately put the whole plant into a state of defense readiness.

There are no important differences between calcium signals which are elicited by mechanical wounding and those which are triggered by feeding caterpillars.

Calcium signals quickly diminished when food - restricted mice were allowed to eat.

Uncontrolled calcium signaling and ROS in the mitochondria is behind a number of common diseases, such as stroke or heart attack, and is thought to play a role in diseases of aging such as neurodegenerative disease.

In our study, pentobarbital inhibited 5 - HT evoked calcium signals in geniculate ganglion neurons and, at anesthetic levels in mice, significantly inhibits 5 - HT3 function in vivo.

Measuring calcium signaling using genetically targetable fluorescent indicators.

Many functional categories of genes were represented in these analyses, including calcium signaling, cytokines, and growth factor pathways.

He also studies the interaction between apolipoprotein E with the α7 nicotinic acetylcholine receptor and dendritic calcium signaling due to activation of α7 - containing nicotinic acetylcholine receptors in rat hippocampal neurons.

The Zeiss Cell Observer Spinning Disc acquires images at 30 frames per second, capturing high - speed biological events, such as calcium signaling, in real time.

This might be because adaptor molecules like RhoH and SLP76 can affect the signaling events downstream of calcium release from the ER, or might indicate the existence for a possible positive feedback pathway from calcium signaling to the upstream of adaptor molecules.

«What we saw in mice lacking STIM1 — whose T - cells can not generate calcium signals — is that the number of mycobacteria in their lungs was dramatically increased, resulting in excessive inflammation,» says Stefan Feske, MD, an associate professor of pathology at NYU Langone and the study's senior author.

However, Feske and his colleagues found that calcium signals also are required for the development of iTreg cells and that their numbers are strongly reduced in the lungs of the infected STIM1 - deficient mice.

«Calcium signaling regulates many important cellular functions, like muscle contraction, neural communication, gene transcription and tissue growth,» said Fenfang Li, a postdoctoral research fellow in Zhong's laboratory and lead author of the study.

Further experiments are planned in order to find out which kind of wounding triggers the systemic calcium signal, for example, whether a similar wound response is elicited by aphids and spider mites, as these insects puncture the plant tissue to suck the plant sap and damage the tissue only slightly.

Current work from Prof. Gaiti Hasan's lab at NCBS has identified new roles for Calcium signalling.

The experiments revealed that the creation of a wound generates a complex series of calcium signals in the surrounding tissue:

The article shows that doses of anesthesia insufficient to affect neuronal responses to whisker stimulation suppressed astrocyte calcium signals.

By micro-injecting IAA directly into the root hair, Julian Dindas also demonstrated that an auxin - treated cell does more than send a calcium signal.

«A simple trick for modeling calcium: A straightforward technique allows for accurate computer simulations of calcium signaling, a key part of countless biological processes.»

First, looking at a study of 185 cases of childhood epilepsy, Wittkowski's team found that mutations in genes that control axonal guidance and calcium signaling — both of which are important early in the developing brain when neurons are forming the appropriate connections — led to increased chances of having the disorder.

Calcium signals are already known to be crucial to neuron development and function.

This means that a calcium signal too weak to turn on c - fos might be made more potent with help from nitric oxide.