Sentences with phrase «called t cells»

Further analysis revealed that microbes (and their fat molecules) normally found in infant guts help to keep inflammation in check and boost the regulatory power of so - called T cells, the worker bees of the immune system.

In their latest work, reported online in the Journal of Clinical Investigation, the scientists analyzed blood from such mice and identified two types of autoimmune response directed specifically against the protein, with the first response directed by a specialized kind of immune system cells called T cells and the second by antibodies.

In the early stages of infection, HIV hides in viral reservoirs in a type of immune cells called T cells.

Normally, two types of immune cells, called T cells and B cells, protect the body from invading viruses, bacteria and fungi.

Without it, immune system cells called T cells, B cells and natural killer cells do not develop normally.

This makes it impossible for sugars on the surface of immune system cells called T cells to attach in multiple spots at once and trigger inflammation.

The so - called T cells are an important example in this regard.

The dendritic cells then stimulated the immune system's main fighters, called T cells, to seek out and kill cancer stem cells — something they do not normally do.

Giving patients a dose of their tumor neoantigens, which look foreign to the immune system, should help activate immune cells called T cells to attack the cancer cells.

These problems are caused by a type of white blood cells called T cells that, after becoming activated, find their way into the brain and attack the protective covering — myelin — of neurons in the brain and spinal cord, causing inflammation and damage to the central nervous system.

In a blood test, immune cells called T cells became activated when exposed to the protein in about 40 percent of Parkinson's patients in a new study.

But before immune - system fighters called T cells will attack foreign tissue, they must first get a confirmation order of sorts: a costimulatory signal.

Immune cells called T cells (shown) are engineered to seek and destroy specific types of cancer.

As the infection progresses, adaptive immune cells called T cells move to the area of infection, where they detect and kill infected cells.

Immune cells called T cells are also activated, in order to kill infected cells.

By manipulating the function of certain immune cells, called T cells, researchers could help restore the system's balance and create new treatments to target these diseases.

Lu's team will extract immune cells called T cells from the blood of the enrolled patients, and then use CRISPR — Cas9 technology — which pairs a molecular guide able to identify specific genetic sequences on a chromosome with an enzyme that can snip the chromosome at that spot — to knock out a gene in the cells.

And unlike current flu vaccines, the new version also fuels a strong reaction from disease - fighting white blood cells called T cells.

Hoping to learn something about how the human body defends itself against cancer, he had zeroed in on a complex regiment of lymphocytes called T cells, common to the immune systems in both mouse and man.

The treatment is a type of so - called CAR T - cell therapy — taking a patient's own immune cells, called T cells, genetically manipulating them to attack specific proteins on cancer, and infusing them back into the patient.

The athletic adults also appeared to have healthier and younger - looking immune systems, at least when it came to an organ called the thymus that's responsible for generating key immune cells called T cells.

The immune system depends on molecules called T cell receptors on the surface of T cells to recognize and respond to foreign antigens from virus - infected cells, tumors and other threats.

Kipnis and his colleagues had previously shown that a type of white blood cell called a T cell (shown above) in the meninges is associated with significant influence on cognition and hence were curious about the role of meningeal immunity on brain function.

Finally, the researchers directly examined a type of lymphocyte called a T cell.

Normally, an immune sentinel known as a dendritic cell would seize an antigen from an invader and present it to another immune cell called a T cell.

Ipilimumab targets a protein called cytotoxic T lymphocytic antigen - 4 (CTLA - 4) that is found on a type of immune cell called a T cell.

For decades, scientists have been seeking a new type of vaccine that activates another player in the immune system called a T cell to fight off infections within different organs.

Not exact matches

The trial involved an experimental checkpoint inhibitor from Bristol - Myers Squibb called ipilimumab (now marketed as Yervoy)-- whose aim was to release the molecular brakes on her own army of T cells.

So researchers, with limited success, have tried to build such a GPS directly into a new type of biological assassin called a «CAR - T cell.»

Kite Pharma, one of the companies chasing a new generation of cancer drugs called chimeric antigen receptor T - cell (CAR - T) therapies, announced a patient death in a clinical trial of its experimental KTE - C19.

«The holy grail is to target a piece of the virus by antibody or t cell,» Tom Evans, the CEO of a company called Vaccitech that is working on a universal vaccine they hope can be used to treat all strains of influenza A, told National Geographic.

What makes the treatment so fascinating is its underlying technology, called chimeric antigen receptor T - cell (CAR - T).

One of the types of cells called into action are T lymphocytes, a type of white blood cell that fights infection.

On Wednesday, the U.S. Food and Drug Administration approved Novartis» Kymriah, the first drug for a new kind of cancer treatment called CAR - T cell therapy.

In 1987 a group of French scientists had discovered a protein protruding from the surface of T cells, which they called CTLA - 4.

Yescarta is a so - called chimeric antigen receptor T - cell (CAR - T) treatment.

Health service chief calls for affordable access to CAR - T, which modifies immune system to destroy cancer cells

The antibody binds to a protein on the surface of T cells called the PD - 1 receptor.

A decade ago a drug based on an internal protein of the flu virus, called NP (for nucleoprotein), set the immune system's killer T cells into action, but it only partially protected mice from the flu.

The new treatments, called CAR T cell therapies, eliminate cancer using people's own cells.

The treatment, called CAR - T immunotherapy, uses genetically engineered T cells, immune system fighters usually tasked with identifying invaders in the body,...

Treating patients with an antibody called pembrolizumab (sold under the brand name Keytruda) caused these T cells to increase in number, says coauthor Kellie Smith, a cancer immunologist at Johns Hopkins University.

These so - called gamma delta T cells account for less than 1 percent of all the cells in the lymph node prior to infection.

The algorithm was built using tools the researchers developed to define how T cell receptors recognize a part of the antigen called the epitope.

The scientists zeroed in on a type of immune cell called regulatory T - cells, which were known to suppress autoimmune responses.

They discovered a population of NKT cells that have a gene that controls so - called regulatory T - cells, whose role is to suppress the immune response.

Nadeau studied immune cells called regulatory T cells, or T - regs.

A second type of immune system cell, called regulatory T cells (Tregs), are a model of constancy, remaining stable even as Teffs go into battle mode.

This is how treatments based on a type of white blood cell called T - cells are curing some cancers, rather than just slowing their advance (see «Cancer meets its nemesis in reprogrammed blood cells «-RRB-.

The so - called STEP trial, sponsored by pharmaceutical giant Merck & Co. and the federally funded HIV Vaccine Trials Network (HVTN), was the first to test the idea of stimulating the immune system's killer T cells to hunt for the virus more aggressively, in this case using a weakened form of the cold virus to carry three genes from HIV.