Another view is that tumors can become resistant to therapy by a process
called cell fate decision, by which some tumor cells are killed by therapy and others become cancer stem cells.
Not exact matches
Specifically, they use a technique
called lineage tracing to mark stem
cells and follow the
fate of their progeny over time.
Using her new culture system, she joined forces with colleagues to research which
cells in an embryo contribute to which parts of the adult animal, a process
called fate - mapping.
The images depict what might be
called embryology in flagrante: micrographs of sperm
cells, trailing accordion - like pleats of white zags as they streak across a vast blue ocean of ooplasm; a multihued blastocyst in the process of hatching out of the egg's zona pellucida; and egg
cells with a fringe of glowing,
fate - determining proteins, looking a bit like a solar eclipse inside a
cell.
FATE MAPPING WITH CRISPR: Thanks to a new tool
called GESTALT, researchers can now introduce a 300 - base - pair lineage barcode into
cells and, using the CRISPR - Cas9 system, allow edits to accumulate as those
cells divide.
Several progenitor
cells,
cells that appear to be committed to their
fate but not yet fully differentiated, have been shown to be capable of dedifferentiating into a different
cell type; this process is
called transdetermination.
The project will focus on answering the question, how an embryonic stem
cell computes cues from its environment to elicit a regulated, exact
cell fate choice during a process
called «differentiation».
He was also the first to describe the role of tiny molecules in the heart —
called microRNAs — which carefully titrate levels of gene activity to control the
fate of
cells.
When BMP turns ES
cells into muscle it activates a protein
called Smad1, a DNA - binding protein that, in opposition to Nanog, switches on genes responsible for muscle
cell fate.
By another twist of
fate, Cuervo soon began to study autophagy — the process by which
cells break down their waste inside organelles
called lysosomes.
OPENING THIS WEEK Kam's Kapsules: Weekly Previews That Make Choosing a Film Fun by Kam Williams For movies opening January 4, 2008 BIG BUDGET FILMS One Missed
Call (PG - 13 for mature themes, frightening images, terror, intense violence and some sexual material) Shannyn Sossamon stars in this remake of Chakushin Ari, a high attrition - rate horror flick from Japan about a traumatized young woman who's afraid to answer her
cell phone after several of her ill -
fated friends receive messages accurately predicting exactly when and how they are about to die.