In contrast, cholesterol was stored in special structures,
called endosomes, which are distinct from lipid droplets in zebrafish intestines.
Also, with some nanoparticles much of the material ends up trapped in protective sacs
called endosomes inside the cell, and there can be potential toxic side effects.
Using lab - grown mouse astrocytes with variant forms of NHE9, the researchers found a change in the pH (acidity) inside cellular compartments
called endosomes, which in turn altered the ability of cells to take up glutamate.
Because certain cell secretion pathways have been suggested to be required for this process, University of Buenos Aires researcher Matías Ostrowski and colleagues investigated whether a role might be played by Rab27a, a protein that guides delivery of membrane - bound compartments
called endosomes to the plasma membrane.
In their latest research, Lawrence Rajendran, of the University of Zurich in Switzerland, and his colleagues discovered that, unlike non-amyloid proteins, the Alzheimer's - associated amyloid precursor protein is cleaved by β - secretase in membrane - bound compartments inside cells,
called endosomes.
Not exact matches
Endosomes are machinery that tumor cells, via a process
called endocytosis, can use to incorporate components into their environment and obtain energy by degrading them via autodigestion or autophagy.
They can fuse with late
endosomes, creating so -
called endolysosomes, which degrade the material within the
endosome.
Sometimes acidity in the
endosome can activate protein - degrading enzymes
called proteases.
The mutant mice with the higher
endosome acidity also had more degradation of a receptor protein,
called TrkB, that responds a neurotrophic factor
called BDNF.