The persistent bacteria uses an enzyme
called isocitrate lyase (ICL) as part of a metabolic pathway that breaks down fatty acids for energy.
The molecule in question is
called isocitrate, which, once produced, can go in two directions: continue the energy production cycle or be taken away to synthesize other parts of the bacterium.
Not exact matches
That case became even stronger with the discovery in 2008 of a mutated gene for a metabolic enzyme
called IDH (
isocitrate dehydrogenase) in some leukemias, brain cancers, and gall bladder and gastrointestinal cancers.