This form of sideroblastic anemia — refractory anemia with ringed sideroblasts (RARS)-- is classified within a broader group of diseases
called myelodysplastic syndromes (MDS) and can eventually lead to leukemia.
Changes in the genetic code (mutations) that reduce TET2 function are found in 10 percent of patients with acute myeloid leukemia (AML), 30 percent of those with a form of pre-leukemia
called myelodysplastic syndrome, and in nearly 50 percent of patients with chronic myelomonocytic leukemia.
Not exact matches
The underlying reason is that Geron and partner Johnson & Johnson (NYSE: JNJ) are developing a first - in - class telomerase inhibitor
called imetelstat for the rare blood disorders
myelodysplastic syndromes (MDS) and myelofibrosis (MF).
In a process
called cellular reprogramming, researchers at Icahn School of Medicine at Mount Sinai have taken mature blood cells from patients with
myelodysplastic syndrome (MDS) and reprogrammed them back into iPSCs to study the genetic origins of this rare blood cancer.
In addition, the cells in the blood and bone marrow (also
called» myelo») usually look abnormal (or «dysplastic»), hence the name «
Myelodysplastic»
Syndromes.