Once dismissed as «junk DNA,» researchers have found that some of these so -
called noncoding regions are shared among mammals, suggesting they play an important function.
«People used to
call the noncoding regions junk DNA, but I see it as a jungle that has not been explored,» said Christopher Gregg, Ph.D., assistant professor in Neurobiology and Anatomy at U of U Health.
Not exact matches
Assessing the influence of individual DNA base changes is particularly difficult in
noncoding regions, so they instead identified bigger alterations, so -
called structural variants, in which large sequences of DNA are inverted, duplicated, or deleted.
Now, a new study probing so -
called noncoding DNA has found that alterations in
regions that regulate gene activity may also contribute to autism.
Like many genes, Dscam consists of protein - coding
regions called exons interspersed with
noncoding regions.