Sentences with phrase «called point mutations»

CRISPR has difficulty correcting these so - called point mutations efficiently and cleanly, so base editing could provide a more effective approach.

Not exact matches

The most pivotal of those experiments involved the development of a novel «knock - in» mouse model in which a point mutation was introduced in GRK2 to prevent NO from binding (a process called nitrosylation).

The mutation, in a gene called HTR2B, prevents production of the serotonin 2B receptor, a key docking point in brain cells for the neurotransmitter serotonin.

Instead, the project can start out by testing participants» DNA for so - called single nucleodtide polymorphism (SNPs), common mutations scattered along the genome that can point to disease risk genes.

The main change, a point mutation in the human gene for hu14.18, was designed to address treatment - limiting pain by generating a more tailored response that avoided triggering part of the immune response called the complement cascade.

By substituting a specific amino acid in a so - called «Notch ligand» encoded by JAGGED1, they found that this single point mutation can interfere with the important Notch signaling system and disrupt communication between the Notch ligand and the Notch receptors.

They used the model to determine how a point mutation in a family of DNA packaging proteins called histone H3 drives formation and the continued growth of DIPG and other high - grade gliomas that develop in and around the thalamus.

This is called a mutation (specifically a point mutation) or variation in the gene.

Malaria infections that were slow to clear were also strongly associated with a single - point mutation in a P. falciparum gene called kelch 13, an important validation of the recently discovered genetic marker (k13) in the DNA of the malaria parasite.

On the other hand, a rare «genetic condition» called progeria — accelerated premature aging — can develop in infants and young children which is not actually genetic in nature yet appears through a «new» point mutation on a specific chromosome.

«There's also a massive amount of features we're giving gamers with this expansion like a dynamic Point of Interest system, a new Gwent deck, new endgame mutation mechanics, and even a place Geralt can call home....