In previous work, Anthony's group and others have found that the anti-inflammatory effect of high - dose IVIG can be attributed to a minor fraction of antibodies to which a glycan
called sialic acid has been attached to their Fc region.
Some of these sugars,
called sialic acids, help tumors hide from the immune system.
Not exact matches
They found that a subtype
called IgA1, which has a special tail at one end that contains
sialic acids, was the most effective.
Since the attachment of
sialic acid to an Fc group requires the presence of another glycan
called galactose, the team created two enzymes termed B4Fc and ST6Fc, which induce the attachment of galactose and
sialic acid respectively.
Bird flu prefers a sugar
called 2,3 -
sialic acid.
One of the
sialic acid - containing molecules gliadin binds to is
called GM1 ganglioside.