Astragalus contains an enzyme
called telomerase, whose anti-aging potential was mentioned in the November 2008 issue of NewScientist.
Successful cancer cells are the ones that have evolved mutations that exploit one of the cell's two systems for renewing telomeres: either a primary system
called telomerase, or in a few cases an «alternative» system appropriately called Alternative Lengthening of Telomeres (ALT).
Telomeres don't shrink significantly in healthy humans for decades due to an enzyme
called telomerase, which partially repairs and lengthens them after each shortening.
The suspected immortalizing agent is an enzyme
called telomerase (tee - LOW - mer - ace) that adds DNA to the endcaps, or telomeres, of the cell's chromosomes.
An enzyme
called telomerase maintains telomeres in our reproductive and stem cells but not in the rest of the body.
An unusual enzyme
called telomerase acts on parts of chromosomes known as telomeres.
As a safeguard, in cells such as egg, sperm, and stem cells, an enzyme
called telomerase is responsible for preventing this wear and tear by maintaining telomere length.
Now two reports show that, with the help of an enzyme
called telomerase, human cells can divide forever in the laboratory without turning cancerous.
One strategy, which occurs in about 90 percent of cancers, requires increase production of a telomere - elongating enzyme
called telomerase.
The variant lies near a gene
called telomerase RNA component, or TERC, and earlier studies in animals have shown that low TERC expression is associated with shorter telomeres, and faster biological aging.
Experiments confirmed that there was an enzyme, which
we called telomerase, and that it is actually doing something inside cells that matters.
The Geron gene made a protein
called telomerase.
The key to immortalization is an enzyme
called telomerase, which keeps chromosomes healthy in cells that divide frequently.
Before now, researchers knew about only one enzyme,
called telomerase, that could delay aging.
Variants in the gene
called Telomerase Reverse Transcriptase (TERT) on chromosome 5 that were associated with older IEAA were also associated with longer telomeres indicating a critical role for TERT in regulating the epigenetic clock, in addition to its established role of compensating for cell replication - dependent telomere shortening.
Not exact matches
The underlying reason is that Geron and partner Johnson & Johnson (NYSE: JNJ) are developing a first - in - class
telomerase inhibitor
called imetelstat for the rare blood disorders myelodysplastic syndromes (MDS) and myelofibrosis (MF).
His co — Nobel laureates, Elizabeth Blackburn and Carol Greider, coauthored a February 1996 Scientific American article
called «Telomeres,
Telomerase and Cancer» and we have re-posted that on our Web site.
Telomerase is an enzyme that replicates the ends of chromosomes (sections of DNA
called telomeres), replacing the DNA lost when chromosomes are copied before cell division and, therefore, maintaining the stability of the genome.
The scientists speculated that when chromosome tips get too stubby — a process that can be reversed by
telomerase, an enzyme made up of protein and RNA — cells cease replicating and enter a state
called senescence (see» More Than a Sum of Our Cells»).
UCLA researchers have found that a Chinese herbal regimen
called TSY - 1 (Tianshengyuan - 1) increased
telomerase activity in normal blood cells but decreased it in cancer cells.
In 2001 researchers at the biotech giant Geron Corporation isolated a molecule
called TA - 65 from the herb astragalus, which they said boosted
telomerase activity (its effect has not yet been evaluated in published, peer - reviewed studies).