In the latest issue of the journal Cell, a team of scientists led by Gladstone Institutes and University of California, San Francisco (UCSF) Investigator Nevan Krogan, PhD, Texas A&M University's Craig Kaplan, PhD, and UCSF Professor Christine Guthrie, PhD, describe a new technique —
called the point mutant E-MAP (pE - MAP) approach — that gives researchers the ability to pinpoint and map thousands of interactions between each of an enzyme's many moving parts.