Sentences with phrase «called the risk mutation»

One of them (called the risk mutation) was more common in patients with Crohn's, while the other (the protective mutation) was more prevalent in patients without the disease.

Not exact matches

Previous studies have shown that inherited mutations in a gene (called TMLHE) that is required for carnitine biosynthesis are strongly associated with risk for development of autism - spectrum disorders, but the basis for that association has been unclear — until now.

Brin writes on his blog that the genome scan of his saliva from 23andMe told him he has a mutation on the LRRK2 gene, a variation called G2019S, which ups the risk for Parkinson's in some families.

Genetic tests for mutations in the so - called breast cancer genes, BRCA1 and BRCA2, may not reveal as much about cancer risk as earlier reports have estimated, according to two studies published in tomorrow's New England Journal of Medicine.

The study builds on Polyak's earlier research finding that women already identified as having a high risk of developing cancer — namely those with a mutation called BRCA1 or BRCA2 — or women who did not give birth before their 30s had a higher number of mammary gland progenitor cells.

People who inherit p53 mutations develop a rare disorder called Li - Fraumeni Syndrome, which confers a near 100 percent risk of developing cancer in a wide range of tissue types.

One mutation, called NQO1 * 2, increases the risk of cancer or cancer relapse, especially for leukemia.

Instead, the project can start out by testing participants» DNA for so - called single nucleodtide polymorphism (SNPs), common mutations scattered along the genome that can point to disease risk genes.

Women with what's called the BRCA mutation have a much higher risk of breast cancer than women without it, according to the National Cancer Institute.

The team found that mutations in a gene called HLA - DRB1 are associated with RA risk in Arab populations just as is the case with Europeans and East Asians, suggesting broad similarities in the genetic structure of RA across ethnic groups.

Those mutations also result in too much of an inflammatory signal called TNFa, and FTD patients have an increased risk of autoimmune disorders in which TNFa has been implicated.

We found mutations in a gene called «POT1» that increased the risk of melanoma in a small number of these families.

If we have changes in them called mutations, and if the mutation significantly increase the risk of a disease (as compared to someone who does not have a mutation in the gene), it is called a high - risk gene.