Sentences with phrase «called zinc finger»

Working with proteins called zinc finger nucleases and TALENs, Zhang attempted to edit the genomes of mammalian cells with a view to engineering them.

The trial is using a form of DNA scissors called zinc finger nucleases (ZFNs).

Last year, researchers targeted and destroyed this gene in the T - cells of 12 people with HIV using custom - made proteins called zinc finger nucleases.

They have used a different technique, called zinc finger nucleases, to disrupt a gene on T cells that HIV uses to enter the cells.

These gene - regulating proteins have an important feature called a zinc finger domain.

Its competitors — designer proteins called zinc finger nucleases and TALENs — also precisely alter chosen DNA sequences, and several companies are already exploiting them for therapeutic purposes in clinical trials.

Talk of curing AIDS made front - page news last year, in part due to an astonishing new gene - editing technology: lab - engineered proteins called zinc finger nucleases.

However, in the presentations, speakers for both teams said that two stretches of the gene code for so - called zinc fingers — protein structures that insert themselves into the grooves of DNA — suggesting that the encoded protein probably turns other genes on and off.

These include a family of signaling molecules called protocaderins, which regulate neuronal development and short - range interactions between neurons, and a family of transcription factors called zinc fingers, which are mainly expressed in embryonic and nervous tissues and are thought to play roles in brain development.

PRDM9 grabs DNA using structures called zinc fingers.

In clinical trials already underway, for example, researchers have used an older gene - editing technique, enzymes call zinc finger nucleases, in immune cells to deactivate the gene for CCR5, a surface protein that HIV latches onto in order to infect cells.

Not exact matches

Ultimately, this week's discourse will lead to a consensus statement providing some guidance on how to approach using this and older gene editing technologies such as zinc finger nucleases and enzymes called transcription activator - like effector nucleases, or TALENs.

In 2009, researchers at Dow AgroSciences in Indianapolis, Indiana, and Sangamo BioSciences in Richmond, California, announced that they had used enzymes called zinc - finger nucleases to insert a gene for herbicide resistance at a specific site in the maize genome (V. K. Shukla et al..

Two groups of researchers - one an academic team from Barcelona, Spain; the other a biotech company from California called Sangamo - have just announced successful experiments using zinc finger drugs targeting the Huntington's disease gene.

When zinc hooks up with a gene - controlling protein, it forms «zinc finger proteins» - so called because they can poke into the tight groove between the two strands of DNA and touch the sequence they're made for.

«There are still some unresolved problems with the so - called zinc - finger method,» says postdoctoral researcher and co-first author Guang - Hui Liu.