RESULTS: Anthocyanin Cy -3-g increased cellular AMPK activity in
a calmodulin kinase kinase dependent manner.
In his recent work, Mesubi found that two proteins (
calmodulin kinase II and O - GlcNAc) are critical to the increased risk for atrial fibrillation for patients with diabetes mellitus.
Cocaine activates calcium /
calmodulin kinase II and causes cardiomyocyte hypertrophy.
Not exact matches
Cunningham and her postdoc at the time, Christine Kirvan, found that the antibodies literally bind to human neurons, activating an enzyme called calcium /
calmodulin - dependent protein (CaM)
kinase II.
When calcium floods a neuron as a memory is formed, it turns on an enzyme called CaMKII (calcium /
calmodulin - dependent protein
kinase).
However, once opiate addiction had developed, the scientists observed a functional switch to a separate molecular memory pathway, controlled by a molecule called
calmodulin - dependent
kinase II or «CaMKII.»
In the course of screening over 180 mutant mouse strains with a systematic battery of behavioral tests, Dr. Tsuyoshi Miyakawa and his colleagues found that mice with heterozygous knockout of the alpha - isoform of calcium /
calmodulin - dependent protein
kinase II (αCaMKII) exhibit behavioral deficits and other brain features consistent with bipolar disorder.
Now, Dong et al. have investigated the consequences of Dab2 downregulation in a new STEM CELLS Translational Medicine study, demonstrating a novel role for calcium /
calmodulin - dependent protein
kinase kinase - 1 (CAMKK1) in the modulation of MSC secreted factors and a potential exciting means to enhance MSC - based cardiac repair [2].
Inactivation of the myocyte enhancer factor - 2 repressor histone deacetylase - 5 by endogenous ca2 / /
calmodulin - dependent
kinase ii promotes depolarization - mediated cerebellar granule neuron survival.
Nucleotides and phosphorylation bi-directionally modulate Ca2 + /
calmodulin - dependent protein
kinase II (CaMKII) binding to the N - methyl - D - aspartate (NMDA) receptor subunit GluN2B.
Protein
kinase C$ ẹlta $ and
calmodulin regulate epidermal growth factor receptor recycling from early endosomes through Arp2 / 3 complex and cortactin.
Molecular interaction and functional regulation of ClC - 3 by Ca2 + /
calmodulin - dependent protein
kinase II (CaMKII) in human malignant glioma.
Neuron 2013) show that increase in intracellular calcium [Ca2 +] i induced by NMDA receptor activation or membrane depolarization strongly activates AMPK through activatoin of Calcium /
Calmodulin - Activated
Kinase Kinase 2 (CAMKK2).
NSP2 functions downstream of Nod - factor - induced calcium spiking and a calcium /
calmodulin - dependent protein
kinase.
Both DAG and calcium are essential second messengers which activate downstream signaling components such as protein
kinase C and
calmodulin dependent
kinase.
Abbreviations: AMPAR, AMPA receptor; AS, Angelman syndrome; BDNF, brain - derived neurotrophic factor; CaMKII, α - calcium /
calmodulin - dependent protein
kinase II; CGN, cerebellar granule neuron; co-IP, coimmunoprecipitation; DG, dentate gyrus; ERK, extracellular signal - regulated
kinase; fEPSP, field excitatory postsynaptic potential; Gab1, Grb2 - associated binder 1; HFS, high frequency stimulation; IGF, insulin - like growth factor; LTP, long - term potentiation; PSD - 95, postsynaptic density protein - 95; SYN, synaptophysin; WT, wild type
We also CREB proteins are activated by phosphorylation from various
kinases, including PKA, and Ca 2 + /
calmodulin - dependent protein
kinases on the Serine 133