Once the cell reaches its destination — the site of inflammation —
the calmodulin protein enters the equation to shed the L - selectin protein, allowing it to enter the inflamed tissue.
Not exact matches
Cunningham and her postdoc at the time, Christine Kirvan, found that the antibodies literally bind to human neurons, activating an enzyme called calcium /
calmodulin - dependent
protein (CaM) kinase II.
For starters, a key
protein called
calmodulin, which helps spindles form, failed to bind to the spindles properly.
Protein immunoblot and histochemical analysis with antiserum to type I NO synthase suggest that the formation of NO in pancreatic B cells is catalyzed by an NADPH -(reduced form of nicotinamide adenine dinucleotide phosphate), Ca2 + /
calmodulin - dependent type I NO synthase of about 150 kilodaltons.
When calcium floods a neuron as a memory is formed, it turns on an enzyme called CaMKII (calcium /
calmodulin - dependent
protein kinase).
Instead, it inhibits
proteins related to
calmodulin, an important calcium binding
protein.
In the course of screening over 180 mutant mouse strains with a systematic battery of behavioral tests, Dr. Tsuyoshi Miyakawa and his colleagues found that mice with heterozygous knockout of the alpha - isoform of calcium /
calmodulin - dependent
protein kinase II (αCaMKII) exhibit behavioral deficits and other brain features consistent with bipolar disorder.
Now, Dong et al. have investigated the consequences of Dab2 downregulation in a new STEM CELLS Translational Medicine study, demonstrating a novel role for calcium /
calmodulin - dependent
protein kinase kinase - 1 (CAMKK1) in the modulation of MSC secreted factors and a potential exciting means to enhance MSC - based cardiac repair [2].
A pollen - specific
calmodulin - binding
protein, NPG1, interacts with putative pectate lyases.
Nucleotides and phosphorylation bi-directionally modulate Ca2 + /
calmodulin - dependent
protein kinase II (CaMKII) binding to the N - methyl - D - aspartate (NMDA) receptor subunit GluN2B.
Protein kinase C$ ẹlta $ and
calmodulin regulate epidermal growth factor receptor recycling from early endosomes through Arp2 / 3 complex and cortactin.
Molecular interaction and functional regulation of ClC - 3 by Ca2 + /
calmodulin - dependent
protein kinase II (CaMKII) in human malignant glioma.
NSP2 functions downstream of Nod - factor - induced calcium spiking and a calcium /
calmodulin - dependent
protein kinase.
Both DAG and calcium are essential second messengers which activate downstream signaling components such as
protein kinase C and
calmodulin dependent kinase.
Abbreviations: AMPAR, AMPA receptor; AS, Angelman syndrome; BDNF, brain - derived neurotrophic factor; CaMKII, α - calcium /
calmodulin - dependent
protein kinase II; CGN, cerebellar granule neuron; co-IP, coimmunoprecipitation; DG, dentate gyrus; ERK, extracellular signal - regulated kinase; fEPSP, field excitatory postsynaptic potential; Gab1, Grb2 - associated binder 1; HFS, high frequency stimulation; IGF, insulin - like growth factor; LTP, long - term potentiation; PSD - 95, postsynaptic density
protein - 95; SYN, synaptophysin; WT, wild type
In his recent work, Mesubi found that two
proteins (
calmodulin kinase II and O - GlcNAc) are critical to the increased risk for atrial fibrillation for patients with diabetes mellitus.
Two
proteins, L - selectin and
calmodulin, are involved in the process.
We also CREB
proteins are activated by phosphorylation from various kinases, including PKA, and Ca 2 + /
calmodulin - dependent
protein kinases on the Serine 133