Not exact matches
Among the most interesting ones identified were those associated with 1) the large category of transport, and the more specific categories of carbohydrate transport and cation: amino acid symport; 2) several related to calcium, including calcium ion binding,
calmodulin binding, and voltage gated calcium channel activity; 3) DNA damage response and
signal transduction; 4) response to oxidative stress; and 5) oxygen and reactive oxygen species metabolism.
Sethna F, Zhang M, Kaphzan H, Klann E, Autio D, Cox CL, Wang H. (2016)
Calmodulin activity regulates group I metabotropic glutamate receptor - mediated
signal transduction and synaptic depression.
Both DAG and calcium are essential second messengers which activate downstream
signaling components such as protein kinase C and
calmodulin dependent kinase.
Abbreviations: AMPAR, AMPA receptor; AS, Angelman syndrome; BDNF, brain - derived neurotrophic factor; CaMKII, α - calcium /
calmodulin - dependent protein kinase II; CGN, cerebellar granule neuron; co-IP, coimmunoprecipitation; DG, dentate gyrus; ERK, extracellular
signal - regulated kinase; fEPSP, field excitatory postsynaptic potential; Gab1, Grb2 - associated binder 1; HFS, high frequency stimulation; IGF, insulin - like growth factor; LTP, long - term potentiation; PSD - 95, postsynaptic density protein - 95; SYN, synaptophysin; WT, wild type