Looking at sixty - seven recent drug discovery projects based on preclinical
cancer biology research, they found that in more than 75 percent of cases the published data did not match up with their in - house attempts to replicate.
Not exact matches
His
research has spanned hematopoiesis, gene therapy, stem cell
biology, genomics and
cancer, consistently focusing on bringing the very latest
research advances to patients with heretofore incurable diseases.
On any given day, Canada's leading researchers unravel the mysteries of
biology in state - of - the - art labs throughout the Toronto Medical Discovery Tower and the Ontario Institute for
Cancer Research; early - stage science and technology companies put business plans into action in the MaRS Incubator; organizations across the innovation spectrum grow their businesses in the Heritage Building — the original brick façade of the old Toronto General Hospital.
You can be a creationist and a scientist, as long as your field has absolutely nothing to do with DNA
research, such as
cancer / molecular
biology, genetics and microbio, because in those fields understanding how DNA changes and is likely to change is fundamental.
In an accompanying editorial, Theodore Slotkin, a professor of pharmacology and
cancer biology at the Duke University School of Medicine in Durham, North Carolina, writes that it's undeniable that smoking while pregnant contributes to later behavior problems in children, based on the new study and past
research.
I'm super interested in the field of molecular
biology and am currently working in a
cancer research lab.
The senior, majoring in
biology, who is
researching the potential of using the spice turmeric to combat pancreatic
cancer, said it was «inspiring» that Biden was pushing for more
cancer research.
Her work in protein
research at Hunter and her grandmother's recent diagnosis of ovarian
cancer sparked an interest in
cancer biology and immunology, but Rezende is eager to sample other fields.
«Everything we talked about was about
research directly on the embryo,» for example, to improve on infertility treatment or better understand cancer biology, says R. Alta Charo, a law professor and bioethicist at the University of Wisconsin Law School who was a member of the NIH Human Embryo Research Panel in the mid-1990s, which considered how embryos might be used in r
research directly on the embryo,» for example, to improve on infertility treatment or better understand
cancer biology, says R. Alta Charo, a law professor and bioethicist at the University of Wisconsin Law School who was a member of the NIH Human Embryo
Research Panel in the mid-1990s, which considered how embryos might be used in r
Research Panel in the mid-1990s, which considered how embryos might be used in
researchresearch.
Ask a cross-section of scientists how they got into
cancer research, and you'll hear about a dizzying variety of routes from fields as diverse as
biology, pharmacology, mathematics, and medicine.
«It was kind of fun being at a medical school and known as the weird guy who worked with dogs,» says Modiano, who is now a professor of comparative oncology at the University of Minnesota College of Veterinary Medicine and the Masonic
Cancer Center, where his research focuses on immunology, cancer cell biology, cancer genetics, and applications of gene th
Cancer Center, where his
research focuses on immunology,
cancer cell biology, cancer genetics, and applications of gene th
cancer cell
biology,
cancer genetics, and applications of gene th
cancer genetics, and applications of gene therapy.
Finally, Andre, originally trained as a physicist, is working in molecular
biology at the Center for
Cancer Research in Bethesda, Maryland.
Armed with his first big discovery, Allison won a full professorship at the University of California, Berkeley, where he became co-chair of the department of molecular and cell
biology and director of the
cancer research lab.
The plenary address titled «Punctuated Equilibrium Meets
Cancer: Big Promise Requires Big Change» will draw from evolutionary biology's punctuated equilibrium theory to set out why stable systems such as cancer research sometimes require swift and fundamental change to ad
Cancer: Big Promise Requires Big Change» will draw from evolutionary
biology's punctuated equilibrium theory to set out why stable systems such as
cancer research sometimes require swift and fundamental change to ad
cancer research sometimes require swift and fundamental change to advance.
After a successful postdoc at the Ontario
Cancer Institute, where he developed a proprietary platform for the discovery of novel cancer therapeutic agents, Bray was asked to join the former Amgen Research Institute in Toronto (now called the Advanced Medical Discovery Institute and no longer part of the parent company) as the head of their quantitative biology group and act as liaison to Amgen Inc. in Calif
Cancer Institute, where he developed a proprietary platform for the discovery of novel
cancer therapeutic agents, Bray was asked to join the former Amgen Research Institute in Toronto (now called the Advanced Medical Discovery Institute and no longer part of the parent company) as the head of their quantitative biology group and act as liaison to Amgen Inc. in Calif
cancer therapeutic agents, Bray was asked to join the former Amgen
Research Institute in Toronto (now called the Advanced Medical Discovery Institute and no longer part of the parent company) as the head of their quantitative
biology group and act as liaison to Amgen Inc. in California.
Many young scientists at the basic
research end of the spectrum will admit that they were initially attracted more by the desire to investigate fundamental questions in
biology than to work specifically on
cancer.
The St. Laurent Institute, a non-profit medical
research institute focused on the systems
biology of disease, today announced in a study published in the July edition of Genome
Biology, that genetic matter, previously ignored by the scientific community, may play an important role in
cancer.
The method can be applied to a range of fields, including clinical settings and fundamental
biology research for
cancer and other diseases.
The University of Sheffield's Department of Oncology and Metabolism conducts world - class
research from basic clinical and translational
cancer research to life course
research and basic level
biology through to diseases such as diabetes and osteoporosis.
Their
research was never driven by curiosity about
biology, Vogelstein says, but by «an overwhelming desire to empty the
cancer clinics across the street.»
«By combining my laboratory's expertise in ovarian
cancer biology and Dr. Xu's expertise in bioinformatics, we were able to uncover a potentially novel drug approach to treat ovarian cancer,» said co-senior author Analisa DiFeo, PhD, the Norma C. and Albert I. Geller Designated Professor of Ovarian Cancer Research and assistant professor in the Case Comprehensive Cancer Center at Case Western Reserve University School of Med
cancer biology and Dr. Xu's expertise in bioinformatics, we were able to uncover a potentially novel drug approach to treat ovarian
cancer,» said co-senior author Analisa DiFeo, PhD, the Norma C. and Albert I. Geller Designated Professor of Ovarian Cancer Research and assistant professor in the Case Comprehensive Cancer Center at Case Western Reserve University School of Med
cancer,» said co-senior author Analisa DiFeo, PhD, the Norma C. and Albert I. Geller Designated Professor of Ovarian
Cancer Research and assistant professor in the Case Comprehensive Cancer Center at Case Western Reserve University School of Med
Cancer Research and assistant professor in the Case Comprehensive
Cancer Center at Case Western Reserve University School of Med
Cancer Center at Case Western Reserve University School of Medicine.
With an M.A. in human genetics and molecular
biology from Johns Hopkins University School of Medicine and a B.S. in biochemistry from New Mexico State University, Cordova has held
research internships at those institutions as well as at the Fred Hutchinson Cancer Research Center and at the University of Texas -
research internships at those institutions as well as at the Fred Hutchinson
Cancer Research Center and at the University of Texas -
Research Center and at the University of Texas - Houston.
During my tenure at NCI, I redirected my
research into expression genomics, an amalgam of
cancer cell
biology and comprehensive and massively parallel genetic technologies.
When factoring in what is now known about breast
cancer biology and heterogeneity, breast conserving therapy (BCT) may offer a greater survival benefit over mastectomy to women with early stage, hormone - receptor positive disease, according to research from The University of Texas MD Anderson Cancer C
cancer biology and heterogeneity, breast conserving therapy (BCT) may offer a greater survival benefit over mastectomy to women with early stage, hormone - receptor positive disease, according to
research from The University of Texas MD Anderson
Cancer C
Cancer Center.
«Students used to say, «I want to understand basic
biology,»» says Tom Curran, a former president of the American Association of
Cancer Research.
«We think that by stopping fibrosis through TAZ and its partners, we may be able to prevent the serious consequences of NASH, including liver failure and liver
cancer,» said Ira Tabas, Richard J. Stock Professor and vice-chair of
research in the Department of Medicine and professor of pathology & cell
biology (in physiology and cellular biophysics) at CUMC.
He subsequently obtained a Ph.D. at the University of Sydney studying
cancer cell biology, and was awarded a Fulbright Fellowship to undertake postdoctoral research at the National Cancer Institute, National Institutes of Health in Bethesda, Mar
cancer cell
biology, and was awarded a Fulbright Fellowship to undertake postdoctoral
research at the National
Cancer Institute, National Institutes of Health in Bethesda, Mar
Cancer Institute, National Institutes of Health in Bethesda, Maryland.
His
research focuses on the
cancer biology, drug resistance, and signaling pathway networks of human diseases as well as on ways to model these disorders.
«This study opens an entirely new area of discovery for many aspects of cell
biology and biomedical
research — how
cancer cells metastasize, for example — and provides many new therapeutic targets,» said senior author Jack Dixon, PhD, professor in the UC San Diego School of Medicine and associate vice chancellor of Scientific Affairs.
Most of the
research into breast
cancer has focused on primary breast
cancer, and there is little understanding of the
biology underpinning breast
cancer that has spread to other parts of the body, known as metastatic
cancer.
This webinar will discuss how integrated HCS imaging systems that have been coupled with novel computer modeling are being applied to systems
biology, translational
cancer research, and personalized medicine.
«AML is a disease in which fewer than 30 percent of patients are cured,» said co-senior author Ulrich Steidl, M.D., Ph.D., associate professor of cell
biology and of medicine and the Diane and Arthur B. Belfer Faculty Scholar in
Cancer Research at Einstein and associate chair for translational research in oncology at Mon
Research at Einstein and associate chair for translational
research in oncology at Mon
research in oncology at Montefiore.
As for next
research steps, the investigators will seek to exploit the SRY database and its evolutionary linkages to other SOX transcription factors to explore applications to stem - cell
biology and
cancer.
He returned to Australia to set up a laboratory at Children's Medical
Research Institute (CMRI) in Sydney, and since that time has been investigating the cellular and molecular
biology of
cancer cell immortalization.
We're now investigating the extent to which these new insights into
cancer biology can be used to develop new therapeutic strategies,» says Professor Roland Rad, explaining the team's next
research goals.
This led to development of newer technology, called single cell sequencing (SCS), that has had a major impact in many areas of
biology, including
cancer research, neurobiology, microbiology, and immunology, and has greatly improved understanding of certain tumor characteristics in
cancer.
Operating within the Hebrew University's Faculty of Medicine, IMRIC coordinates
research within the departmental areas of medical neurobiology, molecular genetics and
biology, immunology and
cancer research.
Soon other researchers began to find more connections between microRNA and
cancer, and microRNA
research began to spread through medicine and
biology — in David Baltimore's words, like «an infection in the laboratory.»
In addition to the implications of this
research for
cancer biology, the development of the alginate - based extracellular matrix model is also significant.
EMBL, meanwhile, has not stood still in defending its position among a pantheon of top European cell
biology research centers, which includes the Imperial Cancer Research Fund (ICRF) in London and the Marie Curie and Pasteur Institutes i
research centers, which includes the Imperial
Cancer Research Fund (ICRF) in London and the Marie Curie and Pasteur Institutes i
Research Fund (ICRF) in London and the Marie Curie and Pasteur Institutes in Paris.
The collaborative
research team — which included experts in gynecological
cancer, genomics, pathology and computational
biology — performed a comprehensive genetic analysis of ovarian and endometrial CSs.
The study was led by Guoping Fan, professor of human genetics and molecular
biology and member of both the Jonsson Comprehensive
Cancer Center and the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell
Research.
The
research, using cells from the Breast
Cancer Now Tissue Bank and due to be published in Nature Communications, also shows that the epigenetic changes are inherited as long as the cell divides, and that the team's manipulations permanently and negatively affected the
biology of a normal breast cell from a healthy individual.
There is really no reliable method for recapitulating the metastatic progression from a primary tumor in the colon to the liver,» says Omer Yilmaz, an MIT assistant professor of
biology, a member of MIT's Koch Institute for Integrative
Cancer Research, and the lead senior author of the study, which appears in the May 1 issue of Nature Biotechnology.
Dr Luca Peruzzotti - Jametti, the first author of the study and a Wellcome Trust
Research Training Fellow, says: «We made this discovery by bringing together researchers from diverse fields including regenerative medicine,
cancer, mitochondrial
biology, inflammation and stroke and cellular reprogramming.
Collaborators include Gabriella Popescu, PhD, professor in the Department of Biochemistry in the Jacobs School of Medicine and Biomedical Sciences at UB; Song Liu, PhD, vice chair of biostatistics and bioinformatics at Roswell Park
Cancer Institute and a
research associate professor in biostatistics UB's School of Public Health and Health Professions; and Marianne Bronner, PhD, professor of
biology and biological engineering, California Institute of Technology.
On Capitol Hill last week, Weinberg, an expert in the molecular
biology of
cancer, pointed out to the Congressional Biomedical
Research Caucus that the major advances in understanding human
cancer genetics had come, not from studying breast tissue, but from studying cow warts, worm vulvas, fruitfly retinas, and a chicken virus.
Founded in 1890, Cold Spring Harbor Laboratory has shaped contemporary biomedical
research and education with programs in
cancer, neuroscience, plant
biology and quantitative
biology.
The aim of the Interdisciplinary Training in
Cancer Research training program is to train young scientists to design and conduct research on significant problems in cancer by combining information and approaches from different scientific disciplines, including basic cellular and molecular biology, epidemiology, clinical trials and studies, and behavioral - social sci
Cancer Research training program is to train young scientists to design and conduct research on significant problems in cancer by combining information and approaches from different scientific disciplines, including basic cellular and molecular biology, epidemiology, clinical trials and studies, and behavioral - social s
Research training program is to train young scientists to design and conduct
research on significant problems in cancer by combining information and approaches from different scientific disciplines, including basic cellular and molecular biology, epidemiology, clinical trials and studies, and behavioral - social s
research on significant problems in
cancer by combining information and approaches from different scientific disciplines, including basic cellular and molecular biology, epidemiology, clinical trials and studies, and behavioral - social sci
cancer by combining information and approaches from different scientific disciplines, including basic cellular and molecular
biology, epidemiology, clinical trials and studies, and behavioral - social sciences.
There are currently 25
research groups in our school and areas of
research in Biochemistry include membrane proteins, enzymology, folic acid biochemistry, structural
biology, tRNA
biology, neurochemistry, neurodegeneration, metabolism, systems
biology,
cancer biology, molecular parasitology, apoptosis and drug discovery.