Sentences with phrase «cancer biology studies»

An effort to replicate dozens of cancer biology studies that were widely cited (bold numbers) has reported its first results: two confirmations, one failure, and two that were inconclusive because of technical problems.

On ScienceInsider, Jennifer Couzin - Frankel reports that the Reproducibility Initiative has received a $ 1.3 million grant from the Laura and John Arnold Foundation to fund the independent validation of 50 important cancer biology studies published between 2010 and 2012.

Not exact matches

In an accompanying editorial, Theodore Slotkin, a professor of pharmacology and cancer biology at the Duke University School of Medicine in Durham, North Carolina, writes that it's undeniable that smoking while pregnant contributes to later behavior problems in children, based on the new study and past research.

His work focuses on applying principles of evolutionary biology and ecology to the study of cancer.

The results, though not surprising, offer a reminder that, with so many people vying for so few tenure - track faculty positions, «trainees need to do more self - analysis of where they are and what the realities are for them to potentially become a faculty member,» says study author Nathan Vanderford, an assistant professor of toxicology and cancer biology and assistant dean for academic development at the University of Kentucky in Lexington.

Our study demonstrates, conversely, that a binary designation of resistance may oversimplify cancer's true biology.

The process of integrating naturally occurring cancers in dogs into the general studies of human cancer biology and therapy is known as comparative oncology.

Commenting on the results for ESMO, Dr Evandro de Azambuja, Head of the Medical Support Team, Academic Promoting Team, Jules Bordet Institute, Brussels, Belgium, said: «This study shows that it's not only tumour size that is important for breast cancer patients but also tumour biology.

GIS's DNA analysistechnique has allowed the researchers to further study the biology of Opisthorchis viverrini to understand the cause and the eventual development of treatments for bile duct cancer, a condition caused by the parasite.

Co-author Dr. David Hinds from 23andMe said: «While the genetics of hair colour is an interesting problem in itself, we hope that better understanding of the biology of melanin pigmentation will be applicable to studies of diseases that interact with pigmentation, such as skin cancer or vitiligo.»

Ana Soto, professor of cellular biology at Tufts University School of Medicine, and her colleagues were studying the effects of estrogen on a breast cancer cell line.

The study, «VlincRNAs controlled by retroviral elements are a hallmark of pluripotency and cancer» found that novel non-coding parts of the human genome known as vlincRNAs (very long intergenic, non-coding RNAs) triggered by ancient viruses, participate in the biology of stem cells, and in the development of cancer.

The St. Laurent Institute, a non-profit medical research institute focused on the systems biology of disease, today announced in a study published in the July edition of Genome Biology, that genetic matter, previously ignored by the scientific community, may play an important role in cancer.

A novel Yale study answers age - old questions about how cancers spread by applying tools from evolutionary biology.

«Forty years ago, very little was known about breast cancer disease biology — such as subtypes, differences in radio - sensitivities, radio - resistances, local recurrence and in metastatic potential,» explains Bedrosian, the study's senior author.

He subsequently obtained a Ph.D. at the University of Sydney studying cancer cell biology, and was awarded a Fulbright Fellowship to undertake postdoctoral research at the National Cancer Institute, National Institutes of Health in Bethesda, Marcancer cell biology, and was awarded a Fulbright Fellowship to undertake postdoctoral research at the National Cancer Institute, National Institutes of Health in Bethesda, MarCancer Institute, National Institutes of Health in Bethesda, Maryland.

«This study opens an entirely new area of discovery for many aspects of cell biology and biomedical research — how cancer cells metastasize, for example — and provides many new therapeutic targets,» said senior author Jack Dixon, PhD, professor in the UC San Diego School of Medicine and associate vice chancellor of Scientific Affairs.

Areas covered range from basic studies into the biology of innate and adaptive immunity (immune cell development and differentiation, immunogenomics, systems immunology, structural immunology, antigen presentation, immunometabolism, and mucosal immunology) to immune contributions to health and disease (host defense, inflammation, cancer immunology, autoimmunity, allergy, transplantation, and immunodeficiency).

Jason Sheltzer, the article's first author, is a graduate student, studying cancer biology at the Massachusetts Institute of Technology (MIT) in Cambridge.

The study's conclusions address a major challenge in current standards of care for prostate cancer: Without knowing a tumor's underlying biology, physicians can not reliably predict which of their patients will develop dangerous forms of the disease.

Mathew Garnett, a cancer biologist at the Wellcome Trust Sanger Institute near Cambridge, UK, says that HeLa cells could prove useful for studying aspects of the biology of cervical tumors, such as their response to cancer drugs.

With VEGF - A and CEA, we believe we may have invented a test that can help that group of patients who don't have a risk of cancer get off the testing cycle and avoid surgery which, in and of itself, has a risk of mortality or complications,» said C. Max Schmidt, MD, PhD, FACS, study author and professor of surgery and biochemical / molecular biology, Indiana University School of Medicine.

The study was published in the December issue of Experimental Hematology, the official publication of the Society for Hematology and Stem Cells, and also highlighted in the journal's editorial due to its significance in the biology and treatment of blood cancer.

Development, oversight, and teaching were coordinated by Kim Petrie, assistant professor of medical education and administration, Rob Carnahan, director of the Antibody and Protein Resource core facility and associate professor of cancer biology, and Joe Rando, associate professor of managerial studies.

The piece was on the biology of lung cancer, which I had written during my studies.

The SFU molecular biology and biochemistry professor is this study's senior author, and the associate director and head of bioinformatics at the B.C. Cancer Agency's Genome Sciences Centre.

The study was led by Guoping Fan, professor of human genetics and molecular biology and member of both the Jonsson Comprehensive Cancer Center and the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research.

«Scientists have learned a lot about development, gene regulation, and cancer biology, among other things, by studying C. elegans.

«In addition to having a higher prevalence of triple - negative breast cancers than Caucasian women — something that has been documented in previous studies — we found that African American women with breast cancer had a significantly higher prevalence of the TP53 driver mutation, basal tumor subtype and greater genomic diversity within tumors, all of which suggest more aggressive tumor biology,» says Tanya Keenan, MD, of the MGH Cancer Center, lead author of the cancer had a significantly higher prevalence of the TP53 driver mutation, basal tumor subtype and greater genomic diversity within tumors, all of which suggest more aggressive tumor biology,» says Tanya Keenan, MD, of the MGH Cancer Center, lead author of the Cancer Center, lead author of the study.

«New insights into the biology of heart failure are desperately needed to prompt new types of targeted therapeutic agents,» says senior study author James Bradner of the Dana - Farber Cancer Institute and Harvard Medical School.

Amanda Curtis drew up a life plan in college that included studying biology in preparation for «spending time in the lab, working on a cure for cancer.»

Dr Toral Gathani, a clinical epidemiologist at the University of Oxford [1], told the 10th European Breast Cancer Conference (EBCC - 10) today (Thursday) that findings from the largest study to date of tumour characteristics in relation to ethnicity suggested that inherent differences in tumour biology between the ethnic groups were unlikely to play a role.

There is really no reliable method for recapitulating the metastatic progression from a primary tumor in the colon to the liver,» says Omer Yilmaz, an MIT assistant professor of biology, a member of MIT's Koch Institute for Integrative Cancer Research, and the lead senior author of the study, which appears in the May 1 issue of Nature Biotechnology.

«Liver cancer is on the rise worldwide, and in human studies we've now seen that patients can progress from fatty liver disease to liver cancer without any middle steps such as cirrhosis,» says David Moore, a professor of molecular and cellular biology, who led the study with Associate Professor Loning Fu, both at Baylor.

Of note, the current study is part of a recent surge in NYU Langone findings on pancreatic cancer, including studies on how first - responder cells turn off the immune response, the role of the drug nab - paclitaxel in tumor biology, cancer cells» unique fuel sources, and how immune cell infighting drives the disease.

Dr Luca Peruzzotti - Jametti, the first author of the study and a Wellcome Trust Research Training Fellow, says: «We made this discovery by bringing together researchers from diverse fields including regenerative medicine, cancer, mitochondrial biology, inflammation and stroke and cellular reprogramming.

For example, Patricia Keely, professor and chair of cell and regenerative biology who studies the matrix surrounding cells, is exploring its link to breast cancer.

They are a couple: Jason Sheltzer, a graduate student studying cancer biology at the Massachusetts Institute of Technology (MIT) in Cambridge, and Joan C. Smith, a software engineer in Twitter's Cambridge office.

On Capitol Hill last week, Weinberg, an expert in the molecular biology of cancer, pointed out to the Congressional Biomedical Research Caucus that the major advances in understanding human cancer genetics had come, not from studying breast tissue, but from studying cow warts, worm vulvas, fruitfly retinas, and a chicken virus.

Focused both on discovery and on mentoring future generations of researchers, Salk scientists make groundbreaking contributions to our understanding of cancer, aging, Alzheimer's, diabetes and infectious diseases by studying neuroscience, genetics, cell and plant biology and related disciplines.

The cancer biology project was inspired by reports from two companies that when they tried to follow up on dozens of papers pointing to potential new drugs, they could not replicate as many as 89 % of the studies.

The aim of the Interdisciplinary Training in Cancer Research training program is to train young scientists to design and conduct research on significant problems in cancer by combining information and approaches from different scientific disciplines, including basic cellular and molecular biology, epidemiology, clinical trials and studies, and behavioral - social sciCancer Research training program is to train young scientists to design and conduct research on significant problems in cancer by combining information and approaches from different scientific disciplines, including basic cellular and molecular biology, epidemiology, clinical trials and studies, and behavioral - social scicancer by combining information and approaches from different scientific disciplines, including basic cellular and molecular biology, epidemiology, clinical trials and studies, and behavioral - social sciences.

«It's probably the single most common gene fusion in human cancer,» said study co-leader Antonio Iavarone, MD, professor of neurology and of pathology and cell biology (in the Institute for Cancer Genetics) atcancer,» said study co-leader Antonio Iavarone, MD, professor of neurology and of pathology and cell biology (in the Institute for Cancer Genetics) atCancer Genetics) at CUMC.

NEW YORK and SEATTLE — April 5, 2018 — The Cancer Research Institute (CRI), Institute for Systems Biology (ISB) and Sage Bionetworks — three organizations on the forefront of cancer immunotherapy, systems biology and bioinformatics — today announced the release of the Cancer Research Institute iAtlas, a comprehensive web - based tool that allows oncologists and researchers to study and analyze interactions between tumors and the immune microenviroCancer Research Institute (CRI), Institute for Systems Biology (ISB) and Sage Bionetworks — three organizations on the forefront of cancer immunotherapy, systems biology and bioinformatics — today announced the release of the Cancer Research Institute iAtlas, a comprehensive web - based tool that allows oncologists and researchers to study and analyze interactions between tumors and the immune microenvirocancer immunotherapy, systems biology and bioinformatics — today announced the release of the Cancer Research Institute iAtlas, a comprehensive web - based tool that allows oncologists and researchers to study and analyze interactions between tumors and the immune microenviroCancer Research Institute iAtlas, a comprehensive web - based tool that allows oncologists and researchers to study and analyze interactions between tumors and the immune microenvironment.

Studying rare familial syndromes can have broad implications to our understanding of cancer biology.

The purpose of the Core for Biomolecular Structure and Function (CBSF) is to provide recombinant protein production, protein characterization, binding studies and structural biology (X-ray crystallography) services to MD Anderson Cancer Center and the wider Texas Medical Center.

And cancer research now involves collaborative efforts from researchers in disciplines such as physics, advanced mathematics, structural biology, nanotechnology, and many more, who have introduced new concepts and approaches to studying cancer.

This census, published in Nature, comprises a first - draft atlas of the small intestine's cellular composition, providing a reference for studying the biology of a host of conditions affecting or involving the gut, such as inflammatory bowel disease, cancers of the small intestine, celiac disease, and food allergies.

For understanding the biology of gene - gene, gene - drug and gene - microenvironment interactions, a considerably broader range of in vitro and in vivo model systems is required — we are generating 1,000 organoid cultures from human cancers, characterising their genomes, functional dependencies and drug response, and we are expanding our in vivo models to study the interface between cancer and the immune system and microenvironment.

We use various approaches including genetics, genomics and cell biology to study gene functions in normal development and disease such as cancer.