Sentences with phrase «cancer brain metastases»
Dr. Anders, a native of Burlington, N.C., an assistant professor in the University of North Carolina at Chapel Hill School of Medicine and a member of the UNC Lineberger Comprehensive Cancer Center, was chosen for her work on the identification of the prognosis and treatment of breast cancer brain metastases.
https://healthtalk.unchealthcare.org/
They and additional co-authors at the MGH Cancer Center, the University of North Carolina, Vanderbilt University and Novartis, identified HER3 — part of the same signaling pathway that includes HER2 — as a possible contributor to anti-HER2 / PI3K resistance in breast cancer brain metastases.
Not exact matches
It offers cardio protection, it helps lower bad cholesterol, it may help prevent the progression of multiple sclerosis, it has the ability to regenerate brain cells after a stroke, it has the ability to cross the blood - brain barrier to potentially ward off Alzheimer's disease, apparently it's good at wiping amyloid plaque from the brain (which studies haves linked to Alzheimer's), it may help to prevent certain types of cancer, and studies have shown that it inhibits cancer cell growth and metastases (meaning it keeps cancer from spreading).
Dr Priscilla Brastianos, MD, a neuro - oncologist and Director of the Brain Metastasis Program at Massachusetts General Hospital, Boston, USA, will say: «Brain metastases are a devastating complication of cancer.
«Brain metastases represent an unmet need in current cancer care.
Approximately eight to ten percent of cancer patients will develop brain metastases, and treatment options are limited.
Many lung cancer trials have traditionally excluded patients with brain metastases at baseline, expecting that the presence of metastases would create negative results that could in turn create the appearance of drug failure.
Research from McMaster University has identified new regulators of brain metastases in patients with lung cancer.
Brain metastases are the most common brain tumour in adults and are a leading cause of death in cancer patiBrain metastases are the most common brain tumour in adults and are a leading cause of death in cancer patibrain tumour in adults and are a leading cause of death in cancer patients.
«If you look at a set of lung cancer patients, like we did in the paper, who develop brain metastases, they all have those two genes in their primary lung cancer,» said Sheila Singh, the study's supervisor, associate professor at the Michael G. DeGroote School of Medicine, scientist with the Stem Cell and Cancer Research Institute at McMaster University and neurosurgeon at McMaster Children's Hoscancer patients, like we did in the paper, who develop brain metastases, they all have those two genes in their primary lung cancer,» said Sheila Singh, the study's supervisor, associate professor at the Michael G. DeGroote School of Medicine, scientist with the Stem Cell and Cancer Research Institute at McMaster University and neurosurgeon at McMaster Children's Hoscancer,» said Sheila Singh, the study's supervisor, associate professor at the Michael G. DeGroote School of Medicine, scientist with the Stem Cell and Cancer Research Institute at McMaster University and neurosurgeon at McMaster Children's HosCancer Research Institute at McMaster University and neurosurgeon at McMaster Children's Hospital.
«Brain metastases are a secondary brain tumour, which means they are caused by cancer cells that escape from primary tumours like lung, breast or melanoma, and travel to the brain,» said Mohini Singh, the study's primary author and a PhD candidate in biochemistry at the Michael G. DeGroote School of Medicine at McMaBrain metastases are a secondary brain tumour, which means they are caused by cancer cells that escape from primary tumours like lung, breast or melanoma, and travel to the brain,» said Mohini Singh, the study's primary author and a PhD candidate in biochemistry at the Michael G. DeGroote School of Medicine at McMabrain tumour, which means they are caused by cancer cells that escape from primary tumours like lung, breast or melanoma, and travel to the brain,» said Mohini Singh, the study's primary author and a PhD candidate in biochemistry at the Michael G. DeGroote School of Medicine at McMabrain,» said Mohini Singh, the study's primary author and a PhD candidate in biochemistry at the Michael G. DeGroote School of Medicine at McMaster.
The study used samples from lung cancer patients with brain metastases.
«Rare mutation may extend survival in lung cancer patients with brain metastases.»
Approximately 30 percent of patients with cancer develop brain metastases, and the incidence of these lesions is rising.
Patients were stratified by number of brain metastases (1 vs. 2 - 3), primary cancer type (melanoma vs. other histology) and pre-operative tumor size (less than vs. greater than three centimeters).
«In cancer, it's usually the metastases to the lung, liver or brain that kill the patient, but it's hard to get tissue safely from these areas,» said Rick Lanman, MD, Guardant Health's chief medical officer.
In the case of breast cancer driven by overexpression of the HER2 gene, up to 50 percent of patients treated with targeted therapies eventually develop brain metastases, which are inevitably fatal.
After confirming in mouse models that cells from HER2 - positive breast cancers became resistant to anti-HER2 treatment when implanted into the brain but not into other tissues, the investigators found that HER3 is overexpressed in brain metastases of HER2 - positive breast cancers from both mice and human patients.
«Metastatic brain tumors — often from lung, breast or skin cancers — are the most commonly observed tumors within the brain and account for about 40 percent of advanced melanoma metastases.
«Stem - cell - based therapy promising for treatment of breast cancer metastases in the brain.»
«Stem cell - based therapy for targeting skin - to - brain cancer: Stem cells loaded with oncolytic viruses show promising results in preclinical models for targeting skin cancer metastases in the brain.»
Tagged therapeutic stem cells (green) are targeting breast cancer metastases (red) in the brain of a mouse model.
«Metastatic brain tumors — often from lung, breast or skin cancers — are the most commonly observed tumors within the brain and account for about 30 percent of advanced breast cancer metastases,» says Khalid Shah, MS, PhD, director of the Molecular Neurotherapy and Imaging Laboratory in the MGH Departments of Radiology and Neurology, who led the study.
Current treatments for both primary brain tumors and brain metastases (cancer that has spread to the brain from another place in the body) are low in number and short on effectiveness.
A phase 3 trial of whole brain radiation therapy and stereotactic radiosurgery alone versus WBRT and SRS with temozolomide or erlotinib for non-small cell lung cancer and 1 to 3 brain metastases: Radiation Therapy Oncology Group 0320.
Novel strategies that are effective in treating brain metastases in patients with lung cancer are needed.
P - glycoprotein mediated efflux limits substrate and drug uptake in a preclinical brain metastases of breast cancer model.
Characterization of passive permeability at the blood — tumor barrier in five preclinical models of brain metastases of breast cancer.
Location: NC1 - 202 Title: «Brain Metastases - Our Advances and Failures» The Department of Cellular and Molecular Medicine welcomes guest speaker Dr. Paul R. Lockman, Professor and Chair Basic Pharmaceutical Sciences, Associate Center Director for Translational Research, West Virginia University Cancer Institute.
Faculty in the Brain and Spinal Tumor Program focus on clinical research and treatment of primary brain tumors, neoplastic meningitis, brain metastases, epidural cord compression, neurotoxicities, anticancer agents, and cancer pain manageBrain and Spinal Tumor Program focus on clinical research and treatment of primary brain tumors, neoplastic meningitis, brain metastases, epidural cord compression, neurotoxicities, anticancer agents, and cancer pain managebrain tumors, neoplastic meningitis, brain metastases, epidural cord compression, neurotoxicities, anticancer agents, and cancer pain managebrain metastases, epidural cord compression, neurotoxicities, anticancer agents, and cancer pain management.
A phase III study of TTFields following Stereotactic Radiosurgery for 1 - 10 Brain Metastases from Non-Small-Cell Lung Cancer more...
Brain metastases are the most common type of brain tumors, and it is estimated that about 1/3 of cancer patients will develop brain metastBrain metastases are the most common type of brain tumors, and it is estimated that about 1/3 of cancer patients will develop brain metastbrain tumors, and it is estimated that about 1/3 of cancer patients will develop brain metastbrain metastases.
For patients with non-small cell lung cancer with brain metastases, treatment with whole brain radiotherapy may not offer much benefit.