Sentences with phrase «cancer cell culture system»

Gelatine methacrylamide - based hydrogels: An alternative three - dimensional cancer cell culture system.

Not exact matches

Glutamine addiction has often been studied in cell culture systems that are genetically altered to overproduce c - MYC, a central regulator of growth and proliferation in all cells that is frequently de-regulated in cancers.

However, this coupling does not exist in cell culture models with exogenously expressed c - MYC — the type of systems that are mainly used to investigate glutamine addiction in cancer.

They tested the system on cell cultures, and then in live mice with breast cancer and mice with constricted arteries in their legs.

Indeed, when JQ1 was added to the 3D culture system, it reversed the genetic changes to the pancreatic cancer cells that the stromal signals had caused.

These results provide the validity to the newly developed hypoxia / reoxygenation culture system for examining the regulation of CSCs in breast cancer cell lines by niche factors in the tumor microenvironment and developing differential targeting strategies to eradicate breast CSCs.

Because the insertion can be placed so that it interrupts a protein's function, the insertion and repair system may be useful for producing certain pharmaceuticals or protein products, such as cancer drugs, in culture, which would otherwise kill the cell.

Their three - dimensional cell - culture system, adapted for high - throughput screening, has enabled them to identify small molecules that can inhibit adhesion and invasion, preventing ovarian cancers from spreading to nearby tissues.

Tags for this Online Resume: cell biology, melanoma, cancer research, bioinformactics, lab manager, systems biology, cell culture, Scientist, grant writing, oncology, research investigator