Sentences with phrase «cancer cell development pathway»
Inhibiting a single cancer cell development pathway with drug therapy can disrupt and may actually increase activity in other pathways and raise the risk of tumors becoming resistant to therapy.
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In addition to the COX enzyme pathway, Dr. Roberts says other studies have shown that aspirin blocks additional cell - signaling cascades that promote cancer development.
Her research has recently shown that a signaling pathway dubbed «hedgehog» is important not only for normal development of stem cells but also for the growth of cancer cells in chronic myelogenous leukemia.
The ERK pathway plays a critical role in embryonic development and tissue repair because it instructs cells to multiply and start dividing, but when over activated cancer growth occurs.
The development of specific inhibitors that target the ERAD pathway could provide useful alternatives to some of the known proteasome inhibitors that stop the growth of cancer cells.
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She is registred to the National Order of Biologists in the province of Palermo; collaboration in research project from 2012 to 2015 at the Department of Biopathology and Biotechnology, University of Palermo, focusing the study on the identification of molecules capable to modulate intracellular metabolic pathways for the prevention and treatment of infectious, tumor and degenerative disease, in collaboration with Prof. Angela Santoni, University of Rome; collaboration in research project in 2011 at the hospital «Villa Sofia Cervello» of Palermo to study methods can cure the genetic defect that causes thalassemia through genetic engineering; she studies different mechanisms of the differentiation and the activation of human gammadelta T cells as effector cells of the immune response against cancer and infectious diseases; she investigates about the identification and development of biomarkers of resistance and susceptibility to Mycobacterium tuberculosis infection; Valentina Orlando has published 13 papers in peer reviewed journals and 3 comunications at national and international congress.
This is why recent work in the field of cancer research has focused on picking apart the complex cellular pathways involved in the development of different cancers and identifying the roles of key proteins involved, with the goal of being able to discriminately and effectively eliminate cancerous cells from the body.
Dr. Freeman's laboratory focuses on the identification and function of T cell costimulatory and coinhibitory pathways in regulating T cell activation and application of this knowledge to the development of more effective immunotherapies for cancer, infections, asthma, and autoimmune diseases.
The scientific goal of the Cancer Biology Program is to identify novel genomic and genetic alterations that play causal roles in cancer development and to study genes, proteins, and signaling pathways that mediate the altered phenotypes of cancer Cancer Biology Program is to identify novel genomic and genetic alterations that play causal roles in cancer development and to study genes, proteins, and signaling pathways that mediate the altered phenotypes of cancer cancer development and to study genes, proteins, and signaling pathways that mediate the altered phenotypes of cancer cancer cells.
She's looking at ways to cripple the stress response pathways of cancer cells to help slow their growth and development.
In his project, Dr. Li is investigating whether beta blockers target T cells to control breast tumor development, and is also working to understand how this pathway regulates T cell responses to tumors, which may reveal novel targets for the immunotherapy of breast cancer.
Researchers are now studying the molecular mechanisms and signaling pathways of cancer cell development, proliferation, and metastasis.
Research now reveals that luteolin has the ability to restrict the activity of the IGF and PI3K cell signaling pathways necessary for the development of cancer found in cancer cells of the colon.
Insulin signalling molecules (including IGF - 1, IGF - 1R and C - Peptide) and pathways (akt / mTOR and Ras / MAPK) have all been linked to increase cancer risk and promotes the development of cancer cells (8).