Sentences with phrase «cancer cell transformation»
Understanding the effects of Eph receptor mutations in cancer cells will help shed light on the role of the Eph receptor / ephrin system in cancer cell transformation, malignant progression and drug resistance.
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They are hypothesized to be the cells that undergo cancerous transformation and cause Merkel cell carcinoma, an aggressive form of skin cancer with no effective treatment.
Thus, the sustained activation which is necessary for a transformation of cells into cancer cells is lacking.
This transformation is triggered by chemical signals, which could be blocked in order to stop cancer cells from spreading.
«The actual transformation into cancer cells is caused by other, unrelated factors and can occur later.
Cancer arises from the transformation of normal cells into tumour cells in a multistage process that generally progresses from a pre-cancerous lesion to a malignant tumour.
Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.
Interestingly, suppression of Dicer activities is reported to result in promotion of epithelial - mesenchymal transistion and metastatic transformation of cancer cells.
Some of their goals include the unravelling of disease mechanisms by using nanomaterials to track cellular components and probe the chemical niche of the cells, the transformation of adult human cells into induced pluripotent stem cells and the delivery of drugs directly to immune and cancer cells.
-- Although endometriosis is benign disease, it shares many of the features of cancer cells with a potential for malignant transformation.
FeLV can cause cancer by directly promoting transformation of normal cells into cancerous cells, and by causing significant immunosuppression, which makes a cat more vulnerable to both infections and cancer.
Cancer occurs when normal cells undergo a transformation whereby they grow and multiply without normal controls.