Sentences with phrase «cancer cells ability»

«Protein key to cancer cells ability to spread identified.»

Not exact matches

We're entering a new frontier in medical innovation with the ability to reprogram a patient's own cells to attack a deadly cancer.

ORAC scores measure the ability of antioxidants to absorb free radicals (that come from pollution and toxins in our environment), which cause cell and tissue damage and can lead to diseases such as cancer.

It offers cardio protection, it helps lower bad cholesterol, it may help prevent the progression of multiple sclerosis, it has the ability to regenerate brain cells after a stroke, it has the ability to cross the blood - brain barrier to potentially ward off Alzheimer's disease, apparently it's good at wiping amyloid plaque from the brain (which studies haves linked to Alzheimer's), it may help to prevent certain types of cancer, and studies have shown that it inhibits cancer cell growth and metastases (meaning it keeps cancer from spreading).

Mogroside V has been found in research to have the ability to inhibit tumor growth in pancreatic cancer by interfering with the rapid dividing of cancer cells, preventing angiogenesis (blood flow to the tumor), and even promoting cancer cell death (10).

Sulforaphane (a sulphur compound) is a key compound in broccoli which has the ability to kill cancer stem cells, which slows tumor growth.

When a tumor is treated with chemo, the tumor may disappear but some cancer stem cells have the ability to survive, and they have the potential to regenerate the original tumor and spread the cancer elsewhere.

In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cells.

These mogrosides are 300 times sweeter than sugar and act as anti-oxidants that have shown abilities to inhibit cancer cell formation (5, 6).

Curcumin in turmeric has the ability to modulate genetic activity and expression — both by destroying cancer cells and by promoting healthy cell function.

But that gives scientists a secret weapon — if they can harness stem cells» natural ability to «home» toward tumor cells, the stem cells could be manipulated to deliver cancer - killing drugs precisely where they are needed.

The spread of cancer by metastasis is driven by a set of mutant proteins called oncogenes which cause cancer cells to multiply uncontrollably and promotes their ability to move.

Now, though, new drugs that disable these checkpoint proteins are showing a keen ability to awaken T cells and, in so doing, pull away cancer's veil.

In a report on the research published March 27 in Nature Genetics, the team says the findings also suggest that such epigenetic variability is a major factor in the ability of cancer cells to proliferate, adapt and metastasize.

The advantages of MFCs may allow widespread use of diagnostic procedures that are currently too expensive to implement (e.g., prescreening for cancer) while the new capabilities may dramatically improve our ability to understand complex diseases such as cancer (e.g., through single - cell analysis).

When the T cells of your immune system are forced to deal over time with cancer or a chronic infection such as HIV or hepatitis C, they can develop «T cell exhaustion,» becoming less effective and losing their ability to attack and destroy the invaders of the body.

He identified gene mutations in breast cancer cells that affect their ability to recognize viruses, including some mutations that would be expected to significantly increase the cells» vulnerability to viruses implicated in breast cancer.

They are also testing inhibitors of JAK2, a molecule that influences ADAR1 activity, for their ability to eliminate cancer stem cells in multiple myeloma models.

It's almost impossible to culture naked mole rat cells in the lab, which made Andrei Seluanov and Vera Gorbunova from Rochester University, New York, wonder if this might be linked to their ability to resist cancer.

Knocking down levels of these thiols reduces cancer cells» ability to resist drugs.

Small populations of adult stem cells with somewhat limited developmental potential are responsible for the body's ability to heal injuries and replace worn out cells and tissues, and evidence is growing that rare cancer stem cells are responsible for the uncontrolled growth of some malignant tumors, including glioblastoma.

This strategy works by sabotaging the ability of the cancer cells to hide from the immune system.

The ability for cancer cells to develop resistance to chemotherapy drugs — known as multi-drug resistance — remains a leading cause for tumor recurrence and cancer metastasis, but recent findings offer hope that oncologists could one day direct cancer cells to «turn off» their resistance capabilities.

The use of proteasome inhibitors to treat cancer has been greatly limited by the ability of cancer cells to develop resistance to these drugs.

They chose drugs that cut off the cancer's ability to burn glucose and shut down protective processes that help cancer cells survive.

«Cdk2 cell cycle kinase seems to play a role in the ability of cancer cells to be more aggressive and resistant to standard chemotherapy,» Dr. Opyrchal said.

They lack the ability to infect cancer cells and therefore can not inject the genetic blueprints for the therapeutic molecules to fight the disease.

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a signaling pathway in cancer cells that controls their ability to invade nearby tissues in a finely orchestrated manner.

In 1998, for example, Wiman's team screened a library of 2000 compounds from the U.S. National Cancer Institute and found two that appeared to restore mutant p53's ability to kill cancer Cancer Institute and found two that appeared to restore mutant p53's ability to kill cancer cancer cells.

Dr. Massagué is particularly interested in the ability of tumor cells to hug blood vessels, as he suspects this behavior may be essential for the survival of metastatic cancer cells not only in the brain but also in other parts of the body where metastatic tumor growth can occur.

Adding two blood - borne proteins associated with cancer cell migration increases the predictive ability of the current biomarker for pancreatic cancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Instcancer cell migration increases the predictive ability of the current biomarker for pancreatic cancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Instcancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer InstCancer Center reports in the Journal of the National Cancer InstCancer Institute.

But this ability to infect brain stem cells may prove useful for fighting deadly brain cancers, many of which are caused by mutated stem cells.

«This meant that the cancer cells maintained their ability to expel the chemotherapy drugs, which limited any enhancement of the cancer therapy.

Higher amounts of insulin are more likely to cause cells to lose their ability to regulate growth, a precursor to cancer.

In our study, as BMI increased, we started seeing an increase in the ability of multiple myeloma cells to adhere, which causes the cancer to better anchor,» DeCicco - Skinner explained.

A phase 3 trial of lenalidomide / dexamethasone plus ixazomib (Ninlaro ®), a «proteasome inhibitor» that blocks the ability of cancer cells to reuse certain proteins.

When combined, these agents cause interactions that significantly disrupt cancer cells» ability to survive DNA damage, according to a preclinical study published in the journal Cancercancer cells» ability to survive DNA damage, according to a preclinical study published in the journal CancerCancer Cell.

«Therefore the ability to eliminate cancer stem cells from the body offers the opportunity to totally eradicate stubborn and residual disease once and for all.

These include the ability to bring new, innovative products to the market; progress in oncology, such as the approval of Genentech's drug Avastin for breast cancer and advances in the use of gene therapy, despite some setbacks; continuing progress in research on stem cells; the emergence of treatments for previously untreated diseases; and solutions for food and fuel shortages, such as biocrops and biofuels.

When the scientists inserted human colorectal cancer cells into zebrafish embryos and allowed them to grow for 4 days, the resulting tumors showed three hallmarks of human solid tumors: rapid cell division, formation of blood vessels to supply nutrients, and the ability to spread to other locations in the body.

(D) When accounting for the reduced efficiency in adherence, the cancer cells display a similar inefficiency in their ability in invade through the collagen of irradiated matrices relative to controls.

This «feedback loop» was crucial for basal - like cancer cells to undergo EMT; reducing AKR1B1 levels impaired the cells» ability to migrate and give rise to cancer stem cells.

With these in vitro test methods, the KU researchers have shown that anti-CD44s antibody can reduce pancreatic cancer cell growth, metastasis and ability of the tumors to recur after radiation therapy.

Metastatic cancer cells have the ability to break free from tissue, circulate in the blood stream, and form tumors all over the body, in a way acting like blood cells.

«A general message from these studies is that cancer cells benefit from modulating epigenetic factors like SIRT6 by acquiring the ability to override normal cellular growth control patterns,» says Mostoslavsky, an associate professor of Medicine at Harvard Medical School and an associate member at the Broad Institute.

Aiolos also represses another protein called p66Shc, which otherwise would suppress metastatic ability, which is the ability of the cancer cells to spread.

New findings published in the Proceedings of the National Academy of Sciences showed in lab studies that supplementing an epigenetic cancer drug called decitabine with vitamin C enhanced the drug's ability to impede cancer cell growth and trigger cellular self - destruction in cancer cell lines.

How it spreads: Unlike normal cancers, where the disease - causing mutation is confined to one organism, devil facial tumor disease (DFTD) cells have evolved the ability to spread from devil to devil.

Now, results described in tomorrow's issue of Nature suggest that BRCA2 mutations could lead to cancer by interfering with cells» ability to repair damaged DNA.

The frenzied reproduction of cancer cells is also a key part of their ability to evade our assaults, because it is essential to their capacity to evolve new solutions to the challenges that we throw up against them.