SEngine employs high - throughput screening to test selected drugs and drug combinations on
cancer cells extracted from your tumor.
Not exact matches
In clinical trials the treatment — which involves
extracting individual patients» immune T -
cells, modifying them to seek out tell - tale biological markers associated with blood
cancers like aggressive lymphoma, and then pumping those modified killer
cells back into the body — has shown major promise, in some cases eliminating all signs of the
cancer in patients six months after treatment.
Those two companies, along with their larger competitor Novartis (nvs), are developing experimental chimeric antigen receptor T -
cell (CAR - T) technology platforms, which are highly personalized treatments that involve
extracting patients» immune
cells, re-engineering them to target their specific
cancers, and then pumping these sniper -
cells back into the body.
This new kind of approach to fighting blood
cancers is truly personalized; immune T -
cells are
extracted from patients, genetically tinkered to home in on an destroy cancerous
cells, multiplied in a lab, and then jolted back into the patient's body within about two weeks.
Research has shown that artichoke leaf
extract has key antioxidants for inducing
cell death (apoptosis) and slowing
cancer cell growth.
In a lab study, an
extract of the leaves stopped the growth and progression of prostate
cancer cells by up to 75 % in mice.
In
cancer research, our goal is to be able to start with a sample of human tissue,
extract many
cells of interest, and perform genetic analysis upon each of them separately.
Furthermore,
extracts of Witchetty bush and Dead finish also showed strong activity against cervical
cancer cells.
Barnes's team went on to show last year that soya
extracts could also inhibit the growth of prostate
cancer cells in laboratory tissue cultures.
«Because the metabolites in
cancer and normal
cells are so different, we
extract and analyze them with the MasSpec Pen to obtain a molecular fingerprint of the tissue.
An enriched hops
extract activates a chemical pathway in
cells that could help prevent breast
cancer, according to new laboratory findings from the UIC / NIH Center for Botanical Dietary Supplements Research at the University of Illinois at Chicago.
When taken separately in low doses, resveratrol and grape seed
extract are not as effective against
cancer stem -
cell suppression as when they are combined together, according to the researchers.
He says that the
extracts from their fibroblasts do contain the sticky substance, but that in spalacids it does not seem to play a key role in the animals» natural resistance to
cancer or activity against
cancer cells in the lab.
The toxicity of chokeberry
extract on normal blood vessel lining
cells was tested and found to have no effects up to the highest levels used (50 ug / ml), suggesting that the
cell death effect is happening in a way other than through preventing new blood vessel formation (anti-angiogenesis), a process that is important in
cancer cell growth.
The study used a well - known line of pancreatic
cancer cells (AsPC - 1) in the laboratory and assessed how well this grew when treated with either the chemotherapy drug gemcitabine or different levels of commercially available chokeberry
extract alone, and when treated with a combination of gemcitabine and chokeberry
extract.
The analysis indicated that 48 hours of chokeberry
extract treatment of pancreatic
cancer cells induced
cell death at 1 ug / ml.
1911 — When F. Peyton Rous takes a
cell - free
extract from a chicken sarcoma and injects it into another chicken, the chicken contracts
cancer too.
«This is the only system that can grow healthy and
cancer cells as if they were just
extracted from a patient, and expand them — a million new
cells can be grown in a week — as long as needed,» he says.
To get around this problem, researchers have been developing sophisticated methods to
extract T
cells from patients, select and expand those that best target a patient's
cancer and reinfuse them into the patient.
Zhao's first experiments involved growing cultures of stromal
cells,
extracting their exosomes and exposing them to
cancer cells, which were then monitored for metabolic changes.
Extracting cancer cells and looking at them under a microscope is the only absolute way to diagnose
cancer.
Cytotoxic effects of bilberry
extract on MCF7 - GFP - tubulin breast
cancer cells.
«Many lung
cancer patients have their diagnosis made by fine needle aspirate — doctors
extract cells via a long needle.
An in depth analysis of this phenomenon reveals that aggressive
cancer cells are «parasites» that use oxidative stress as a «weapon» to
extract nutrients from surrounding stromal
cells.
The
extract was tested in laboratory studies using colon
cancer cells grown in culture.
They next
extracted these same domains from 35 colorectal
cancer cell lines, most of which had been generated by Markowitz and his colleagues.
«Some approaches to creating
cancer vaccines begin by
extracting a patient's own immune
cells, priming them with tumor antigens and returning them to the patient, a process that is complex and expensive,» says Mark Poznansky, MD, PhD, director of the MGH Vaccine and Immunotherapy Center and senior author of the report.
As noted above, existing
cancer vaccines that use dendritic
cells require
extracting cells from a patient's blood, treating them with an engineered protein or nucleic acid that combines tumor antigens with immune - stimulating molecules, and returning the activated dendritic
cells to the patient.
To prove the hypothesis that an XMRV - infected
cell line had contaminated the prostate
cancer samples in the 2006 Urisman, et al. study, we analyzed available RNA
extracts using a novel technique referred to as mitochondrial RNA (mtRNA) profiling.
Avocado
extract has also been shown to inhibit prostate
cancer cell growth in vitro.
Research has demonstrated that avocado
extract inhibits and kill
cancer cells, indicating that the consumption of avocados could help protect against
cancer.
A 2006 University of Florida study showed that
extracts from açai berries destroyed cultured human
cancer cells!
Researchers in India recently conducted
cell studies showing that one benefit of Ashwagandha is that its
extract disrupts
cancer cells» ability to reproduce in certain types of
cancers [1 - 7], and laboratory analysis indicates that Withania somnifera
extract possesses some level of anti-tumor activity and may mitigate many of the negative effects of chemotherapy [1 - 7].
The study was for
extracts applied directly onto
cancer cells, no?
Other studies have examined other natural plant
extracts with anti-
cancer activity such as garlic, broccoli, raspberries, blueberries, carrots, ginger, onions and others and they all have been identified as having the ability to target
cancer cells.
A study carried out by the department of Dermatology, University of California in June of 2011 involving 830 people comparing various vitamins found that the group taking grape seed
extract experience a 74 percent reduction in squamous
cell carcinoma — a type of skin
cancer.
Grape seed
extract has shown some promise in a number of laboratories looking at
cancer cell lines.
There are studies that show regular consumption of grape seed
extract may be responsible for both preventing
cancer and triggering
cancer cells to self destruct.
The lead author Xiangin Shi, PhD., professor in the Graduate Center for Toxicology at the University of Kentucky said: «What everyone seeks is an agent that has an effect on
cancer cells but leaves normal
cells alone, and this shows that grape seed
extract fits into this category.»
-- Thymic
extracts have been shown to normalize and modulate the ratio of T - helper
cells to suppressor
cells whether the ratio is low as in AIDS, chronic infections and
cancer, or high as found with allergies and autoimmune diseases like psoriasis and rheumatoid arthritis.
An Arabian study found that ginger
extracts suppressed the growth of breast
cancer cells, while an animal study at University of Minnesota showed that mice with colorectal
cancer that received gingerols had 75 percent fewer tumors than the control group.
His research is an investigation into how dandelion tea root
extract «reminds» the
cancer cells to commit suicide, without harming any healthy
cells in the process.
In a laboratory study published in the Journal of Nutritional Biochemistry, an
extract of avocado containing these carotenoids and tocopherols inhibited the growth of both androgen - dependent and androgen - independent prostate
cancer cells.
But there's more to the health benefits of carrots than that: studies have demonstrated the ability of carrot
extracts to inhibit the grown of colon
cancer cells.
A study funded by the US Public Health Service studied the effects of pomegranate juice on prostate
cancer cells taken from patients and determined that pomegranate
extract was able to slow down the growth of
cancer in these
cells.
Dr. Lui examined the effect of a whole ginger
extract containing 5 % gingerol on a number of different ovarian
cancer cells..
The Swedish researchers concluded that
extracts from organically grown strawberries halted
cancer cell proliferation more effectively than
extracts from conventionally grown ones, and in both types of
cancer cells.
A study published in the Journal of Agriculture and Food Chemistry focused on identifying the means by which fruit
extracts or their components provide protection against human liver
cancer cells.
In fact, in a 2004 study published in the Journal of Agricultural and Food Chemistry, it was concluded that chlorogenic acid antioxidants may prevent the proliferation of four kinds of
cancer cells, suggesting green coffee bean
extract may even help to prevent
cancer.
Research has shown that Dulse
extracts inhibited HeLa
cell proliferation that is found in human cervical adenocarcinoma and has also been found to reduce the risk of intestinal
cancer and breast
cancer, or mammary
cancer.