Sentences with phrase «cancer cells from a blood»

Vortex's system uses a microfluidic chip to generate tiny vortices that trap larger, more deformable cancer cells from a blood plasma sample.

The device has been used to separate different blood components, to separate cancer cells from blood and to manipulate nanorod motors inside living cells, to name only a few research areas.

So my field is science and technology, so my work is circulating tumor cells where I isolate cancer cells from blood of patients and isolate their DNA and RNA and try to sequence them and try to device treatments for cancer treatment and therapy.

The experimental test uses a plastic chip whose microscopic inner surfaces are covered in antibodies to grab cancer cells from the blood.

Memorial Sloan Kettering Cancer Center's Dr. Howard Scher notes in the NCI piece that plucking the cancer cells from blood is just the start.

The chip would allow the filtering of cancer cells from a blood sample, which would be an easier way to harvest cancer cells, rather than the current method of taking them from tumor sites in the body.

Not exact matches

Consider: Last year alone, the FDA approved two treatments, from Novartis and Gilead, that literally reengineer patients» immune T - cells to target and destroy blood cancers.

This new kind of approach to fighting blood cancers is truly personalized; immune T - cells are extracted from patients, genetically tinkered to home in on an destroy cancerous cells, multiplied in a lab, and then jolted back into the patient's body within about two weeks.

It offers cardio protection, it helps lower bad cholesterol, it may help prevent the progression of multiple sclerosis, it has the ability to regenerate brain cells after a stroke, it has the ability to cross the blood - brain barrier to potentially ward off Alzheimer's disease, apparently it's good at wiping amyloid plaque from the brain (which studies haves linked to Alzheimer's), it may help to prevent certain types of cancer, and studies have shown that it inhibits cancer cell growth and metastases (meaning it keeps cancer from spreading).

Breast cancer tumors can fuse with blood vessel cells, allowing clumps of cancer cells to break away from the main tumor and ride the bloodstream to other locations in the body, suggests preliminary research.

For over one hundred years, scientists have debated the question of the origins of the lymphatic system — a parallel system to the blood vessels that serves as a conduit for everything from immune cells to fat molecules to cancer cells.

Cancer cells can break away from a primary tumor, penetrate into lymphatic and blood vessels, circulate through the bloodstream, and grow in a distant focus (metastasize) in normal tissues elsewhere in the body.

The researchers confirmed this hypothesis by showing that if they blocked YAP1 they could inhibit stem cells from undergoing self - renewal, forming blood vessel - like structures, and reduce lung cancer cell growth in mice.

In their latest study, they tested compounds against cells from nine different types of human cancer, including common types affecting blood, colon, breast, prostate, ovaries, kidneys, and lungs.

The results of the empirical study show a clear distinction between the damage to the white blood cells from patients with cancer, with pre-cancerous conditions and from healthy patients.

To seed in the brain, a cancer cell must dislodge from its tumor of origin, enter the bloodstream, and cross densely packed blood vessels called the blood - brain barrier.

Adding two blood - borne proteins associated with cancer cell migration increases the predictive ability of the current biomarker for pancreatic cancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Instcancer cell migration increases the predictive ability of the current biomarker for pancreatic cancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Instcancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer InstCancer Center reports in the Journal of the National Cancer InstCancer Institute.

In experiments on normal and MLL cells from mice and humans, the researchers demonstrated that beta - catenin is activated in cancer stem cells that prompt leukaemic blood cells to multiply.

Researchers at Dana - Farber / Boston Children's Cancer and Blood Disorders Center report promising outcomes from a clinical trial with patients with a rare form of bone marrow failure who received a hematopoietic stem cell transplant (HSCT) after pre-treatment with immunosuppressive drugs only.

From a simple blood draw, the test reads the DNA of the patient's immune repertoire to find the immune cell barcodes associated with the cancer.

A DEVICE that filters cancer cells from human blood using sound could help to identify tumour cells that have spread.

Fat cells cultured from the body mass index of a morbidly obese patient cause multiple myeloma cells to anchor to a much greater extent than normal cells and produce a significantly larger number of blood vessels to sustain the cancer cells.

The cancer cells spread from one place in the body to another, through the blood vessel.

Metastatic cancer cells have the ability to break free from tissue, circulate in the blood stream, and form tumors all over the body, in a way acting like blood cells.

The stem cells, derived from human umbilical cord - blood and coaxed into an embryonic - like state, were grown without the conventional use of viruses, which can mutate genes and initiate cancers, according to the scientists.

Scientists from the German Cancer Research Center (DKFZ) have developed a way to equip mouse blood stem cells with a fluorescent marker that can be switched on from the outside.

«We began with stem cells taken from cord - blood, which have fewer acquired mutations and little, if any, epigenetic memory, which cells accumulate as time goes on,» says Zambidis, associate professor of oncology and pediatrics at the Johns Hopkins Institute for Cell Engineering and the Kimmel Cancer Center.

In this study, researchers took cells from patients with blood cancer MDS and turned them into stem cells to study the deletions of human chromosome 7 often associated with this disease.

In a process called cellular reprogramming, researchers at Icahn School of Medicine at Mount Sinai have taken mature blood cells from patients with myelodysplastic syndrome (MDS) and reprogrammed them back into iPSCs to study the genetic origins of this rare blood cancer.

Lymphoma is a type of blood cancer that affects the white blood cells — called lymphocytes — that help protect the body from infection.

In their investigation, Greaves and colleagues discovered incipient cancer cells in routine blood samples taken from the child at birth, strongly suggesting that the transmission happened in utero.

Now a team of researchers in China has developed a new microfluidic chip that can quickly and efficiently segregate and capture live circulating tumor cells (CTCs) from a patient's blood, with potential applications for cancer screenings and treatment assessments.

As a result, these blood vessels will be structured more tightly, which can prevent cancer cells from spreading to other organs.

«FDG PET shows tumor DNA levels in blood are linked to NSCLC aggressiveness: Insights derived from FDG PET could improve treatment selection for patients with advanced non-small cell lung cancer.»

To make the vaccine, cancer cells are harvested from a tumor after surgery and stripped of their proteins; then those proteins are cultured with dendritic cells, a subclass of white blood cells, drawn from the patient's blood.

He did, however, publish a paper last year documenting a study in which he infused three cancer patients with white blood cells from young donors who had been injected with G - CSF.

A study combining tumor cells from patients with breast cancer with a laboratory model of blood vessel lining provides the most compelling evidence so far that a specific trio of cells is required for the spread of breast cancer.

Living in overcrowded conditions appears to protect children and young adults against developing a particular type of Hodgkin lymphoma (HL), a cancer that originates from the lymphocytes (white blood cells).

To understand how these multi-colored lesions originated they examined blood from these mice and found that tumor cells in circulation frequently occurred as clusters comprised of different colored cancer cells.

Some of the first evidence for cancer stem cells came from studies of leukemia in the 1990s, which showed that only a small subset of the cancerous blood cells could propagate the disease in mice.

Analyzing white blood cells from 934 patients and 1,698 healthy controls, they found BRCA1 methylation among 6.4 % of patients diagnosed with ovarian cancer, contrasting 4.2 % among controls.

Next, T cells — the immune system's foot soldiers — are harvested from the patient's blood and infected with the virus, which rewrites their genetic code to recognize and destroy cancer cells.

In recent studies of cancer patients who received a bone marrow transplant, genes from the marrow's white blood cells were found in the patient's tumor cells.

The SC3 tool was then used to analyse single - cell RNA - sequence data from two patients diagnosed with myeloproliferative neoplasm (MPN) blood cancers.

HSCT is effectively used today as a form of «replacement» therapy for patients with hard - to - treat blood cancers, providing healthy cells from either the patient (autologous transplantation) or from a donor (allogeneic transplantation) to better equip patients to fight the disease on their own.

Cheng, an assistant professor of medicine in hematology / oncology at Feinberg, provided the cell lines and NanoFlare targets the researchers used to model blood samples taken from breast cancer patients.

Abatacept, when added to the standard drug regimen used to prevent GvHD, reduced the occurrence of acute, grade III - IV GvHD from 32 to 3 percent in pediatric and adult patients who underwent mismatched unrelated donor stem cell transplants to treat advanced cancer and other blood disorders.

Adds Liu: «With metastatic cancers accounting for around 90 % of deaths from solid tumors, the hope is that one day a device that can enable the analysis of single tumor cells circulating in the blood could make a big difference in early diagnosis, detection and monitoring of numerous types of cancer, without invasive biopsies.»

The researchers identified the LSC17 score by sampling the leukemia stem cell properties of blood or bone marrow samples from 78 AML patients from the cancer centre combined with molecular profiling technology that measures gene expression.

Recently, scientists have engineered cells from a patient's own immune system to fight blood cancers.