Sentences with phrase «cancer cells in lab»

Half a continent away, Buckanovich was doing his own studies on the role that the same protein played in the growth of ovarian cancer cells in his lab at the University of Michigan.

This study found that turmeric extract reduced the growth of certain types of cancer cells in a lab setting.

They grew pancreatic cancer cells in lab dishes and fed them both glucose and fructose.

But this humble substance has also been studied for its biological activity against more serious matters like cancer cells in lab tests.

We investigate organoids, the latest way that scientists are growing cancer cells in the lab to help test hundreds of cancer drugs.

Muehlenbachs said further study was limited by the patient's death and the fact that researchers have been unable to grow tapeworm cancer cells in the lab.

Wang's team discovered that if human lung cancer cells in a lab dish in the presence of the receptor were treated with BCX, they migrated less than untreated ones.

In a May 2014 study, Nagrath and colleagues found that highly aggressive ovarian cancer cells were glutamine - dependent and that depriving the cells of external sources of glutamine — as some experimental drugs do — was an effective way to kill late - stage ovarian cancer cells in the lab.

They grew the cancer cells in the lab and injected them into mice.

«Compound in magnolia may combat head and neck cancers: Honokiol, from magnolia bark, shuts down cancer cells in lab.»

Their study, published in the ACS journal Chemical Research in Toxicology, found that triclosan, as well as another commercial substance called octylphenol, promoted the growth of human breast cancer cells in lab dishes and breast cancer tumors in mice.

He says that the extracts from their fibroblasts do contain the sticky substance, but that in spalacids it does not seem to play a key role in the animals» natural resistance to cancer or activity against cancer cells in the lab.

«We have shown that our molecule works on cancer cells in the lab, but the next step is to see if it works on real tumors in animals.

«But cancer cells in the lab don't necessarily indicate the response of human tumors,» Håkansson reminds the group.

A COMPOUND that slows the proliferation of triple - negative breast cancer cells in lab tests could lead to the first drugs to target this aggressive type of tumour.

The team found that if they raised glutathione levels in cancer cells in the lab, they reversed resistance to the drug erlotinib, and the treatment was once again able to kill cancer cells.

Not exact matches

This new kind of approach to fighting blood cancers is truly personalized; immune T - cells are extracted from patients, genetically tinkered to home in on an destroy cancerous cells, multiplied in a lab, and then jolted back into the patient's body within about two weeks.

In a lab study, an extract of the leaves stopped the growth and progression of prostate cancer cells by up to 75 % in micIn a lab study, an extract of the leaves stopped the growth and progression of prostate cancer cells by up to 75 % in micin mice.

In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cellIn 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cellin the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cellin mice and in lab cultures, and it also prevented the growth of new tumor cellin lab cultures, and it also prevented the growth of new tumor cells.

Researchers at Tufts Medical School noticed that cancer cells being grown in the lab multiplied more quickly in polyester test tubes than in glass.

The lab that I work in is primarily interested in understanding how and why certain cancers are more likely to spread to the skeleton, and my personal project has focused on uncovering new mechanisms that the cancer cells use to communicate with other cells in the bone.

One of his professors, Dag Jenssen, persuaded Helleday to join his lab in the Department of Genetics, Microbiology, and Toxicology at Stockholm University to investigate the importance of recombination in somatic cells, tumor cells, and cancer initiation.

By studying human cancer cells and animal models of cancer in the lab, our researchers have shown that loss of PTEN leads to high levels of PI (3,4) P2, which could result in hyperactivation of AKT.

Previous work in Weinberg's lab had shown that after a tumor forms in one part of the body, some of the cancer cells undergo EMT, Mani explains.

The NB activity in Alberta is far ranging, with such research as self - assembled nanostructures (M. J. Brett), single - cell cancer analysis (L. M. Pilarski), computational modeling (D. Wishart), micro-total analysis systems or lab on a chip (D. J. Harrison), cell identification and manipulation (K. Kaler), and microsystems and medical diagnostics (Backhouse).

Each of the four compounds was then tested in the lab to see how it would affect a line of prostate cancer cells relatively sensitive to the chemotherapeutic Paclitaxel, commonly used to treat prostate cancer patients.

It's almost impossible to culture naked mole rat cells in the lab, which made Andrei Seluanov and Vera Gorbunova from Rochester University, New York, wonder if this might be linked to their ability to resist cancer.

Daniel Chen, a postdoc in Dogic's lab, imagines that someday the droplets could be controlled to deliver drugs or seek out cancer cells.

In lab tests, they show that one such particle can be produced in plants and it ferries small molecules to cancer cellIn lab tests, they show that one such particle can be produced in plants and it ferries small molecules to cancer cellin plants and it ferries small molecules to cancer cells.

By hitting breast cancer cells with a targeted therapeutic immediately after chemotherapy, researchers from Brigham and Women's Hospital (BWH) were able to target cancer cells during a transitional stage when they were most vulnerable, killing cells and shrinking tumors in the lab and in pre-clinical models.

Bloch's colleagues at the National Institute of Environmental Health Sciences tested the oils in gene expression studies on lab - grown human breast cancer cells and found that they could mimic estrogens, the primary female sex hormones, and inhibit androgens, the primary male sex hormones.

Previous work in the lab of CU Cancer Center investigator, Carol Sartorius, PhD, and others shows that progesterone aids the expansion of CK5 + cells.

Lab testing showed that the plant - made virus particles, which naturally bind to receptors on cancer cells, were taken in by human breast cancer cells.

However, along with this seemingly linear storyline in which retinoids block progesterone's promotion of CK5 + cells, previous work in the lab of CU Cancer Center investigator Peter Kabos, MD, and others shows that breast cancers treated with anti-estrogen drugs like tamoxifen or aromatase inhibitors show an increased population of CK5 + cells — it is as if these therapies remove the roadblock of estrogen - dependent cells, leaving CK5 + cells to proliferate.

After the modified T cells make many copies of themselves in the lab, they're unleashed in the patient's bloodstream to find and kill cancer cells.

The biomarker panel, enabled by discovery work of first author Jungsun Kim, PhD, a postdoctoral fellow in Zaret's lab, builds on a first - of - its - kind human - cell model of pancreatic cancer progression the lab described in 2013.

«As it has been shown to be selective to cancer cells and non-toxic to normal cells in the lab, this peptide has the potential to be safe, but further work would be required to prove that.»

When Conklin joined his lab, he had no experience in his PI's core area of cancer research, but he brought valuable expertise in cell imaging techniques.

New findings published in the Proceedings of the National Academy of Sciences showed in lab studies that supplementing an epigenetic cancer drug called decitabine with vitamin C enhanced the drug's ability to impede cancer cell growth and trigger cellular self - destruction in cancer cell lines.

The group looked at an oncogene, AF1q discovered in Tse's lab, which is expressed in hematological cancer cells and is known to be related to multiple myeloma.

To create the switch, biomolecular engineer Marc Ostermeier and colleagues marshaled a protein found in high levels in cancer cells to activate a second protein that he built in the lab.

So when biologists in Catharina Svanborg's lab saw mothers» milk kill cancer cells, they knew they were onto something big.

From tissue and cell samples from five glioblastoma patients, the scientists obtained 33 individual cancer cells capable of reproduction, which grew into very different tumors in the lab.

Experiments showed that HIFs controlled the production of GSTO1 in breast cancer cells when they were exposed to chemotherapy; if HIF activity was blocked in these lab - grown cells, GSTO1 was not produced.

To understand how cancer cells could have an established tolerance, Santagata and Peter Tsvetkov, a postdoctoral researcher in the Lindquist lab, analyzed the genes that allow cells to survive exposure to proteasome inhibitors at toxic levels.

Until now, little was known in preclinical models about the mechanisms that allow breast cancer cells to leave the latent state and even less is known in patients,» explains Roger Gomis, head of the Growth Control and Cancer Metastasicancer cells to leave the latent state and even less is known in patients,» explains Roger Gomis, head of the Growth Control and Cancer MetastasiCancer Metastasis Lab.

They tested these drugs one at a time for lethal interaction with 112 different tumor - suppressor gene mutations in human cancer cells growing in the lab.

Another is that the transplanted bits of tumor act nothing like cancers in actual human brains, Fine and colleagues reported in 2006: Real - life glioblastomas grow and spread and resist treatment because they contain what are called tumor stem cells, but tumor stem cells don't grow well in the lab, so they don't get transplanted into those mouse brains.

«This is why some cancers can be so difficult to treat with chemotherapy, because the cells can be in different states — some sensitive to treatment and some resistant to treatment, all in the same tumor,» says Sandro Santagata, a former visiting scientist in the lab of Whitehead Member Susan Lindquist.

As a doctoral student in the lab of Drs. Margaret Wheelock and Keith Johnson at the University of Toledo, Dr. Islam focused on identifying a link between cadherins (a family of cell adhesion proteins) and tumorigenesis (start of cancer cell formation).