Not exact matches
For the first time, scientists have directly observed events that lead to the formation of a
chromosome abnormality that is often found in
cancer cells.
Perera's paper in
Cancer Epidemiology Biomarkers and Prevention linked the chromosomal aberrations, which were somewhat higher than normal, to air pollution: On average, the higher the hydrocarbons in the mothers» air, the more frequent the
abnormalities seen in the infants»
chromosomes.
Chromosome mis - segregation leads to aneuploidy, which is the leading cause of miscarriages and chromosomal
abnormalities and is also linked to
cancer.
Her finding provided one of the first indications that
chromosome abnormalities could play a role in
cancer.
The Philadelphia
chromosome or Philadelphia translocation (Ph) is a specific genetic
abnormality in
chromosome 22 of leukemia
cancer cells (particularly chronic myeloid leukemia (CML) cells).
The discovery of the Philadelphia
chromosome, which revolutionized
cancer research by making the connection between genetic
abnormalities and
cancer
Telomeres protect a cell's
chromosomes from fusing with each other or rearranging —
abnormalities which can lead to
cancer — and so cells are normally destroyed when their telomeres are consumed.