Sentences with phrase «cancer drug»
But these repurposed anticancer drugs such as antifungals and painkillers may represent the future of cancer drug research, according to leaders of the ReDO project.
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It shows that cancer drug targets behave very differently from normal proteins and often have a complex web of social interactions, like a Facebook super-user.
«Scientists combine a peptide with a nano cancer drug formulation to improve treatment effectiveness and prevent metastasis in pancreatic cancer.»
Researchers from BIND Biosciences in Boston filled nanoparticles with the cancer drug docetaxel and injected them into the blood of 17 people who had cancers that are normally resistant to the drug.
An alternative approach is to cause rapid cell aging and induce premature senescence, which we believe could become a new frontier in cancer drug development.»
Later this year, they'll seek FDA approval for a new cancer drug and request an additional application for Arcalyst, their first product on the market.
When scientists reported 2 years ago that mice with certain gut bacteria responded best to a powerful new type of cancer drug, other researchers were intrigued but cautious — mice, after all, aren't humans.
A surprising, paradoxical relationship between a tumor suppressor molecule and an oncogene may be the key to explaining and working around how breast cancer tumor cells become desensitized to a common cancer drug, found researchers at the Perelman School of Medicine at the University of Pennsylvania.
Apart from a few studies in mouse models and in cell lines, there is no laboratory evidence that synthetic phosphoethanolamine works as a cancer drug.
In the early 2000s, Danishefsky — who is best known for synthesizing Taxol (paclitaxel), a small - molecule cancer drug derived from the Pacific yew tree — set his sights on synthesizing EPO that would be identical to that in the body.
«Murine study finds potential boost for ovarian cancer drug Olaparib.»
This drug - triggered relationship induces the expression of the oncogene c - Myc, leading to reduced sensitivity to the cancer drug and eventually relapse.
Advocacy groups, meanwhile, pressured politicians and health authorities to legalize use of the compound as a cancer drug.
The study is also gratifying for the handful of researchers pursuing vitamin C, or ascorbic acid, as a cancer drug.
A scientist on a mission to develop an assay that allows her team to advance a new cancer drug may take on the project with a commitment that goes far beyond the norm.
So Charlotte Willans from the University of Leeds, UK, and colleagues subjected silver to the same treatment as platinum to see if they could make an effective cancer drug.
«New breast cancer drug defeats the Ras genes notorious for causing many types of cancer.»
NIH supports both innovation and «optimization that can benefit patients — such as making a cancer drug less toxic or more potent,» says Andilibi, now program director of the US National Cancer Institute's Small Business Innovation Research (SBIR) Development Center in Bethesda, Maryland.
The chief aim of I - SPY 2, according to Esserman and others, is to collapse the time it takes to get a green or red light for a potential new breast cancer drug from 10 years to 1 year.
In just the past few weeks, the news has buzzed about a skin cancer drug that may cure Alzheimer's, an osteoporosis medication that can kill malaria parasites, a leukemia drug that inhibits the Ebola virus, and many more.
A U.S. biotechnology company has found early success with a cancer drug developed by a supercomputer, BBC reports.
The three Ras genes found in humans — H - Ras, K - Ras and N - Ras — were among the first to be linked to cancer development, and a new study led by VCU Massey Cancer Center researcher Paul Dent, Ph.D., has shown the recently approved breast cancer drug neratinib can block the function of Ras as well as several other oncogenes through an unexpected process.
«Scientists build a better cancer drug to pass through blood - brain barrier.»
Adult fruit flies given a cancer drug live 12 % longer than average, according to a UCL - led study researching healthy aging.
We were able to extend their lifespan both genetically and by using a cancer drug to target the Ras pathway, which provides us with the first evidence for the anti-aging potential of drugs developed to dampen this pathway.»
The Bidens» wish list ranges from giving patients more control over their medical data to launching «a national conversation» about cancer drug pricing.
In one recent trial, researchers showed that a combination of FDG and HER2 - targeted PET imaging was 100 percent accurate in predicting patient responses to a costly new anti-HER2 breast cancer drug.
An oral cancer drug improves outcomes while minimizing side effects in women with gynecologic cancers who carry a BRCA mutation and whose disease is not responding to other therapies, suggests preliminary research.
Swedish researchers have started a clinical trial to assess whether a prostate cancer drug could help prevent pedophilic behavior — and they're counting on online donations to help finish it.
Several years ago, for example, poor chemical probe data led researchers to pursue a final stage clinical trial on a cancer drug candidate called iniparib.
Others include an older skin cancer drug that last year helped alleviate Alzheimer's symptoms in mice and antibodies that bind directly to beta - amyloid and remove it.
As a cancer drug, BEZ235 works by inhibiting the PI3K and mTOR metabolic pathways, which help fuel the unchecked cell division that is a hallmark of cancer.
Its storied history includes its packaging for human trials of a failed cancer drug, azidothymidine (AZT), in the 1980s, after a young NIH investigator named Sam Broder — later director of the National Cancer Institute — decided to investigate whether it would work to treat AIDS.
New findings published in the Proceedings of the National Academy of Sciences showed in lab studies that supplementing an epigenetic cancer drug called decitabine with vitamin C enhanced the drug's ability to impede cancer cell growth and trigger cellular self - destruction in cancer cell lines.
St. Jude Children's Research Hospital scientists have reported a promising new approach that uses an investigational cancer drug to dial down viral production and dramatically increase survival of flu - infected mice.
The scientists identified several, including the investigational cancer drug BEZ235, which blocked a key metabolic pathway in flu - infected human lung epithelial cells.
«Powerful method to speed cancer drug discovery unveiled.»
Professor Michael Seckl, lead author from the Department of Surgery and Cancer at Imperial said: «Although these are very early - stage results, and are yet to be applied to patients in trials, they suggest the addition of a very cheap diuretic may extend the amount of time we can use the cancer drug erlotinib.
The team studied a lung cancer drug called erlotinib which can be used to treat between 10 and 30 per cent of lung cancer patients.
Adult drug resistant cancer cells may contribute to this problem, and the authors discuss these and other cancer drug resistance mechanisms in their recent publication in the September issue of the journal Cancers.
Wahl and Li imagine ReBiL being used in the future to discover new interactions between proteins that might serve as cancer drug targets, as well as being used in robotic systems to identify drugs that disrupt protein interactions.
«Future comparative oncology studies, optimizing the delivery of PMed strategies, may aid cancer drug development.»
«Breakthrough technique combats cancer drug resistance: Researchers «turn off» multi-drug resistance capabilities in cancer cells.»
A new type of cancer drug developed at Johns Hopkins University in Baltimore, Maryland, but not yet tested in clinical trials may have triggered the deaths of three patients who were undergoing an alternative cancer treatment by a nonmedical practitioner in Germany.
«A cancer drug like Taxol for instance is made from old yew trees, which naturally produce the substance in their bark.
«Naturally occurring mechanism of cancer drug - resistance may itself be a treatment target.»
Indeed, one small trial gave Alzheimer's patients the same cancer drug that looked promising in mice — but it failed.
«Taking a standard prostate cancer drug with food boosts impact, lowers cost: Savings per patient could reach as high as $ 300,000.»
Half of the patients treated in this study responded to either ponatinib (typically used for certain types of leukemia) or pazopinib (a kidney cancer drug), depending on the genetic alterations identified through sequencing.
Tamara Minko and colleagues at Rutgers University in New Jersey decided to encapsulate the lung cancer drug doxorubicin in fatty bubbles that are small and light enough to be inhaled.