This can be important because emerging evidence suggests that tiny proteins excreted with exosomes can drive reactions that may become major barriers to effective
cancer drug delivery and treatment.»
He has helped found at least two dozen biotech companies, with foci ranging from
cancer drug delivery to products for hair and skin.
Not exact matches
PERTH - based Medi - tech Research Limited may be on the brink of a major advance in
cancer therapy with its hyaluronic acid technology for the
delivery of anti-
cancer drugs.
Dr. McCabe said nanoparticles are a leading - edge technology also being studied for
delivery of
drugs for other conditions, such as
cancer, heart disease, and bacterial infections, in order to target specific cells to reduce toxicity and side effects of those medications and to make them more effective.
While researchers have long worked with nanoparticles for
drug delivery, the findings put forth by He and his team represent a crucial breakthrough in addressing multidrug resistance in
cancer cells.
«Future comparative oncology studies, optimizing the
delivery of PMed strategies, may aid
cancer drug development.»
Liang Xu, Ph.D. member of the KU
Cancer Center's
Drug Discovery,
Delivery and Experimental Therapeutics program and associate professor of molecular biosciences at KU, has discovered that targeting a cell - surface receptor called «CD44s» can block pancreatic tumor formation and recurrence after radiotherapy.
The nanorods could have applications in such areas as electronics, sensory devices, energy conversion and storage,
drug delivery, and
cancer treatment.
As their novel technique for
drug delivery is non-invasive and easy to use, the NUS team envisioned that the microneedles patch has great potential for applications in clinical and home care settings for the management of perioperative pain and chronic pain in patients suffering from conditions like diabetes and
cancer.
«New magnet - based
drug delivery system shows promise for
cancer treatment.»
Or, if you built a nanosubmarine, you might want to seal a
drug inside for
delivery to a
cancer cell that you wanted to kill.
«Nanoparticles combine photodynamic and molecular therapies against pancreatic
cancer: Novel
drug -
delivery system cuts off common treatment escape pathways in animal models.»
A nanoparticle
drug -
delivery system that combines two complementary types of anticancer treatment could improve outcomes for patients with pancreatic
cancer and other highly treatment - resistant tumors while decreasing toxicity.
iRGD is therefore potentially useful to optimize the
delivery of
cancer drugs by the nanoparticle to the tumor.
Researchers have created a new
drug delivery system that could improve the effectiveness of an emerging concept in
cancer treatment — to dramatically slow and control tumors on a long - term, sustained basis, not necessarily aiming for their complete elimination.
Scientists at Rutgers University have developed a targeted
drug delivery system that they believe could make ovarian
cancer more treatable and increase survival rates for the most deadly gynecological
cancer in the United States.
«The more we learn about
cancer through these probes, the more opportunities we have to apply them — which means more chances to treat different
cancers, hopefully cure them, and at least prevent their spread and maximize
drug delivery.»
After injecting them into the bloodstream, we are able to gather them around the tumour using magnets and ensure that they don't kill the healthy cells,» explains Asst Prof Xu, who has been working on
cancer diagnosis and
drug delivery systems since 2004.
This means that these devices have the potential to be used in the human body in the future in applications such as
drug delivery and locating
cancer cells.
A team of MIT researchers has now hijacked that
delivery system for a different purpose: administering
cancer drugs.
That is, they have engineered a
drug delivery system so that the very enzymes that make
cancers dangerous could instead guide their destruction.
Many more years of work remain before this or a similar
drug -
delivery system can be tested in humans with inoperable bone
cancer, the researchers said.
This is the first demonstration of effective
delivery of antibody mimics into cells, which could allow researchers to develop new
drugs for
cancer and many other diseases, says Pentelute, the senior author of the paper.
His research interests include medicinal chemistry, nanotechnology,
drug delivery, cell trafficking and molecular imaging for theranostic applications in
cancer and Alzheimer's disease (AD).
We are particularly interested in leverage our interdisciplinary expertise in polymer chemistry, nanomedicine,
drug delivery and immunobiology to innovate new approaches to modulate the tumor microenvironment and enhance cellular immune responses to
cancer vaccines.
A promising discovery for advanced
cancer therapy reveals that the efficiency of
drug delivery in DNA nanostructures depends on their shapes, say researchers at Missouri University of Science and Technology and the University...
Microvesicle - and exosome - mediated
drug delivery enhances the cytotoxicity of Paclitaxel in autologous prostate
cancer cells.
The qNano system was presented to Prof... I am very excited that qNano will help us in accelerating our translational efforts in nanoparticle based
drug delivery for affordable therapies in
cancers and other diseases worldwide.»
Apart from the various biomedical applications of nanomaterials, especially in
cancer therapy, cellular uptake of nanoparticles is a key factor in recent years for efficient
drug delivery applications.
Because of their unique properties such as monodispersity, large surface area and high
drug loading efficiency, silica nanoparticles (SiNPs) have been developed for a vast array of biomedical uses such as optical imaging,
cancer therapy, targeted
drug delivery and controlled
drug release for genes and proteins.
While some research has been done on using apoferritin for
drug delivery, this is the first time it was used to target lung
cancer cells.
A bioengineer in the College of Engineering and Computer Science at Florida Atlantic University has received a $ 141,743 grant from the National
Cancer Institute of the National Institutes of Health to develop a novel biodegradable polymer stent that will be designed to prevent complications while at the same time serving as a drug delivery system for esophageal cancer th
Cancer Institute of the National Institutes of Health to develop a novel biodegradable polymer stent that will be designed to prevent complications while at the same time serving as a
drug delivery system for esophageal
cancer th
cancer therapy.
A new
drug delivery system for treating lung
cancer allow chemotherapeutic
drugs to be inhaled, thereby delivering the
drug where it is needed while reducing the harmful effects to other organs.
Antibody -
drug conjugates (or ADCs) are an innovative
cancer treatment in which a chemotherapy
drug is attached to an antibody that facilitates
delivery into target
cancer cells.
Yes, nanotechnology is becoming ubiquitous in our daily lives and has found its way into many commercial products, for example, strong, lightweight materials for better fuel economy; targeted
drug delivery for safer and more effective
cancer treatments; clean, accessible drinking water around the world; superfast computers with vast amounts of storage; self - cleaning surfaces; wearable health monitors; more efficient solar panels; safer food through packaging and monitoring; regrowth of skin, bone, and nerve cells for better medical outcomes; smart windows that lighten or darken to conserve energy; and nanotechnology - enabled concrete that dries more quickly and has sensors to detect stress or corrosion at the nanoscale in roads, bridges, and buildings.
While cautioning that the new radiation
delivery system is still far from ready for use in people, Abraham notes that P32 gives off high energy that can penetrate through 5 millimeters of human tissue, making it a good candidate to tackle colon
cancer since colon
cancer cells can often form large, thick tumors into which
drugs may not penetrate very well.
Researchers have developed a new
delivery system for
cancer treatment that attacks the condition simultaneously with three different
drugs.
Some of their goals include the unravelling of disease mechanisms by using nanomaterials to track cellular components and probe the chemical niche of the cells, the transformation of adult human cells into induced pluripotent stem cells and the
delivery of
drugs directly to immune and
cancer cells.
Results have shown that the co-
delivery of an anti-
cancer drug (paclitaxel) with a highly potent anti-tumor «messenger molecule» (IL - 12 encoded plasmid2) using the carrier suppressed
cancer growth more efficiently than the
delivery of either paclitaxel or the plasmid in mice bearing 4T1 breast
cancer.
RALEIGH, NC — Researchers at North Carolina State University and the UNC School of Medicine have developed a new
drug delivery technique that uses a biodegradable liquid metal to target
cancer cells while limiting toxicity to normal cells.
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