Sentences with phrase «cancer drug targets»
His lab is now further investigating how this happens in hopes of identifying possible cancer drug targets for tumors that arise in obesity.
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Wahl and Li imagine ReBiL being used in the future to discover new interactions between proteins that might serve as cancer drug targets, as well as being used in robotic systems to identify drugs that disrupt protein interactions.
Breast, uterine, and ovarian tumors often use these receptors to boost their growth, and many cancer drugs target them.
Their contributions to the yeast community include physical mapping methods, synthetic lethality screen approaches for identifying cross-species candidate genes as potential cancer drug targets, and a widely used set of vectors and yeast host strains that have been instrumental in work that has led to countless discoveries in recent decades.
«Team decodes structure of protein complex active in DNA repair: Search for new inflammatory disease, cancer drug targets aided by detailed structure.»
It shows that cancer drug targets behave very differently from normal proteins and often have a complex web of social interactions, like a Facebook super-user.
We believe cancer drugs targeting this pathway could be a viable option for future immunotherapies.»
«Kinesin - 5 structure opens cancer drug targets.»
«Blocking its function causes cancer cells to die, making Bcl - xL an important cancer drug target.
Current projects in the laboratory include: 1) functional screens of ubiquitin ligases to identify novel cancer drug targets; 2) defining the molecular regulation of breast cancer metastasis to the brain; and 3) understanding signaling pathways that influence the response of cancer cells to chemotherapy.
You'll learn how to use canSAR to enhance selection of new cancer drug targets - currently a major focus area to reduce attrition in the clinic.
«The task was to find the rogue proteins in cancer and go after them and spare the normal cells,» says Buolomwini, who later founded the journal Current Cancer Drug Targets to chronicle the field.
Many cancer drugs target one of the soldier proteins that have already been expressed from a gene, have received marching orders from other proteins, and are well on their way to causing problems, such as metastasis.
At stake this time is Barbacid's plan to raise private money to work on a potential cancer drug target his team recently discovered, a plan the government has called «illegal.»
Search for new inflammatory disease and cancer drug targets aided by detailed structure, according to Penn study
Wang points out that the current findings are preliminary and that comparing SLC13A5 activity in healthy and cancerous human liver tissue will be necessary before studies of this pathway as a cancer drug target should be contemplated.
The findings are «an exciting step forward in the validation of telomerase» as a cancer drug target, says Louis Zumstein, a molecular biologist at Introgen Therapeutics in Houston, Texas.
Nearly a third of all cancer drugs target G protein - coupled receptors, of which fractalkine is one, so «we reasoned that blocking it may prevent or reduce ovarian cancer metastasis, because it's expressed in 64 percent of metastatic ovarian carcinoma specimens,» Barbolina said.
Cellecta specializes in negative screens (i.e. viability or drop - out) to identify cancer drug targets.