Not exact matches
«Today's approval marks another first in the field of
gene therapy — both in how the
therapy works and in expanding the use of
gene therapy beyond the
treatment of
cancer to the
treatment of vision loss — and this milestone reinforces the potential of this breakthrough approach in treating a wide - range of challenging diseases,» FDA Commissioner Scott Gottlieb said in a statement.
«Steep funding cuts for the federal health agencies are counterproductive at a time when innovative research is moving us closer to identifying solutions for rare diseases, new prevention strategies to protect Americans from deadly and costly conditions, advances in
gene therapy, new technologies for understanding the brain, and
treatments that harness the ability of our immune system to fight
cancer.»
These include the ability to bring new, innovative products to the market; progress in oncology, such as the approval of Genentech's drug Avastin for breast
cancer and advances in the use of
gene therapy, despite some setbacks; continuing progress in research on stem cells; the emergence of
treatments for previously untreated diseases; and solutions for food and fuel shortages, such as biocrops and biofuels.
«Today's approval marks another first in the field of
gene therapy — both in how the
therapy works and in expanding the use of
gene therapy beyond the
treatment of
cancer to the
treatment of vision loss — and this milestone reinforces the potential of this breakthrough approach in treating a wide - range of challenging diseases,» FDA Commissioner Scott Gottlieb said in a statement.
As a new generation of
gene therapy clinical trials shows promise to cure or halt the progression of several rare diseases, the time has come to explore ways to pay for the cutting edge
treatments, a pediatric hematologist - oncologist from Dana - Farber / Boston Children's
Cancer and Blood Disorders Center argues in a commentary published by the journal Science.
Although the
treatment worked in only two of 17 patients, the researchers say this proof of concept, reported online today in Science, should pave the way for more
gene -
therapy cancer cures.
The research suggests the possibility, Kahn explains, of developing
gene therapy treatments using fat cells that aid in treating metabolic diseases,
cancer or other conditions in the liver or other organs.
The first
gene therapy was bone marrow engraftment for the
treatment of leukemia and other blood
cancers.
«RNAi
therapies are a unique approach to
cancer treatment as they have the potential to «turn off» the genes» coding for proteins involved in cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.&
cancer treatment as they have the potential to «turn off» the
genes» coding for proteins involved in
cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.&
cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper
Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.&
Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a
cancer cell to block the expression of specific proteins involved in tumor growth.&
cancer cell to block the expression of specific proteins involved in tumor growth.»
Newer
cancer treatments, like adoptive T cell
therapy, use a variety of ways to strengthen T cells for the fight and He says the mouse receptor
genes could be another way to do that.
At a time when
gene therapy has been revived as a potent form of
cancer treatment, a new approach would use nanoparticles, rather than viruses, to deliver strands of DNA or RNA to tumors.
Hence, scientists have begun studying BRCA - targeted
gene therapy as an effective
treatment for breast
cancer.
These so - called «living drugs» — injected T cells genetically modified to better recognize and kill tumor cells through a perpetual process of cell renewal and expansion — are revolutionizing
cancer treatment, with the first two FDA approvals of such
gene - altering
therapies occurring in just the last two months.
This specificity in
treatment fits with an emerging approach in
cancer treatment nationwide, known as personalized medicine, in which the
therapies for each patient are selected based on the
genes altered in their tumors.
Inhaled
gene therapy for lung
cancer could be a future
treatment if tested properly.
From the development of insulin and transplant surgery to modern day advances, including
gene therapies and
cancer treatments; animals — from mice to monkeys — continue to play a crucial role in both basic and applied research.
A significant percentage of children and young adults with
treatment - resistant B - cell leukemia achieved remission through a new CAR T - cell
gene therapy that destroys
cancer cells with the CD22 molecule on its surface.
The recent FDA approval of a
gene therapy for leukemia
treatment marks a new frontier in medical innovation for the field of
cancer immunotherapy.
We learn which specific
genes are expressed in
cancer cells and how a patient may respond to different
therapies, so that we can select the most appropriate targeted
treatment for the particular
cancer.
The co-delivery of small molecular drugs with nucleic acids can improve
gene transfection efficiency, reduce side - effects of these drugs, and achieve the synergistic effect of drug and
gene therapy for the more effective
treatment of
cancer.
Great strides have been made in pediatric
cancer and childhood disease
treatment over the past few decades, and recent advances in the areas of
gene therapy, immunotherapy and targeted
therapy will continue to move the field forward in 2017.
Every day we read about some drug,
gene therapy, or
treatment that holds promise for control, if not eradication, of
cancer.
Robyn Elmslie, D.V.M., veterinary oncologist at the Veterinary Referral Center (VRC) of Colorado, and her husband Steven Dow, D.V.M., Ph.D., an immunologist at the National Jewish Medical Research Center in Denver, have been evaluating
gene therapy for the
treatment of
cancer.
Morris Animal Foundation funds studies researching
gene therapies for canine
cancer treatment and reports some success in treating osteosarcoma, melanoma, soft tissue sarcomas, and lymphomas3.
The good news is that
treatment and cure of animal
cancers is proceeding apace: early detection through imaging technology and a range of
treatments including radiation
therapy, chemotherapy, improved surgical techniques,
gene therapy, radioactive beads, and a special diet for the
cancer patient are all in the news.
The mission of ACGT is to support the extraordinary potential offered by cell and
gene - based
therapies to accelerate effective and safe
treatment of all types of
cancer.