These results, published in Nature Communications, have the potential to improve current
cancer immunotherapy strategies, especially in relation to the prevention of metastasis (dissemination of the tumor to organs distant from the site of origin).
CRI provides a pilot grant to Jean - Pierre Mach for preclinical studies to test a new
cancer immunotherapy strategy using anti-tumor antibody fragments conjugated to antigenic MHC / peptide complexes.
Not exact matches
«Discovery opens door to new
strategy for
cancer immunotherapy.»
In addition to formulating diagnostic
strategies for
cancer immunotherapy agents, her team is focused on developing a deep understanding of tumor immune biology as well as mechanisms associated with immune response and immune escape in
cancer patients, with the intent of generating rational
strategies for the creation of combination therapies.
So Swanton is focusing on
immunotherapies —
strategies that help the immune system to recognize and destroy
cancer cells.
The results show that generation of an optimal immune response to
cancer requires cooperation between two types of memory T cell — one circulating in the blood and the other resident in tissues — that can be reactivated with current
immunotherapy strategies.
«Our results in experimental models of
cancer suggest a new therapeutic
strategy based on inhibiting the microRNA machinery — or the Let - 7 microRNAs — specifically in the TAMs, which may unleash the power of mainstream
immunotherapies, such as immune checkpoint inhibitors.»
Through such an understanding it will be possible to block the tumor's immune evasion
strategy which in turn will result in the
cancer patient responding more effectively to an anti-
cancer immunotherapy.
She translates the most promising
immunotherapy strategies for breast
cancer to the clinic, and is now extending these
strategies to ovarian
cancer.
Targeting negative regulators downstream of the TCR represents a novel
strategy to improve
cancer immunotherapy.
«The IASLC, being a global, multidisciplinary organization, is uniquely positioned to coordinate a harmonized
strategy that can bring people together to show how the culture of lung
cancer should reflect hope, as advances in lung
cancer screening and early detection, personalized therapies, and
immunotherapies are making a real impact in patients» lives.»
We are developing cutting - edge discovery platforms and product
strategies for effective
cancer immunotherapies that we believe take into consideration the limitations of other approaches, as well as leveraging different mechanisms of action to address the risk of reliance on a single approach.
This has led to a successful
strategy for
cancer immunotherapy: block the pathways that tumors use to turn off the immune response.
The intent of the effort is to build off the identified immunologic factors that may be modulated to improve
immunotherapy for CRC patients, with the goal that the biomarkers and treatment
strategies identified in the manuscript will become part of the routine management of colorectal
cancer (CRC).
«Insights derived from these data will be critical to improving the effectiveness of current
cancer immunotherapy treatments and developing new immune - based treatment
strategies,» said Justin Guinney, Ph.D., principal investigator, director of computational oncology and bioinformatics at Sage Bionetworks.
Cancer immunotherapy is showing huge promise as a cancer treatment str
Cancer immunotherapy is showing huge promise as a
cancer treatment str
cancer treatment
strategy.
A novel approach to
cancer immunotherapy —
strategies designed to induce the immune system to attack
cancer cells — may provide a new and cost - effective weapon against some of the most deadly tumors, including ovarian
cancer and mesothelioma.
In an effort to accelerate the development, refinement, and approval of more
cancer immunotherapies, the Cancer Research Institute has a developed a comprehensive strategy that draws upon several complementary resources and pro
cancer immunotherapies, the
Cancer Research Institute has a developed a comprehensive strategy that draws upon several complementary resources and pro
Cancer Research Institute has a developed a comprehensive
strategy that draws upon several complementary resources and programs.
In doing so, he is devising inventive
strategies to circumvent the hurdles that prevent
immunotherapy from being cost - effective, widely available and effective against many types of
cancer.
Although
cancer immunotherapy is changing the paradigm of how
cancer is treated, there is an urgent need to develop predictive biomarkers to identify patients who are most likely to benefit from various immunotherapeutic
strategies.