Sentences with phrase «cancer in a large cohort»

Friday, Oct. 20, 5:30 - 5:50 p.m., South Hall B, South Building Featured Plenary Abstract: The contribution of rare variants, polygenic risk, and novel candidate genes to the hereditary risk of breast cancer in a large cohort of breast cancer families N. Li, Peter MacCallum Cancer Center, et al

Fuchs and colleagues (1999) prospectively examined the relationship between Dietary Fiber intake and the risk of colon cancer in a large cohort of women.

Not exact matches

While further study of larger patient groups with longer follow - up times is needed for this cohort of prostate cancer patients, this study is pivotal in providing evidence for change in practice.»

Several large cohort studies of medical x-ray technicians and nuclear industry workers suggest a slight increase in cancer risk at exposures below 100 mSv, Shore says.

To identify the relevant mutations the scientists analyzed the blood samples of 1,858 men from three independent cohorts in Europe and North America: the Swiss arm of the European Randomized Study for Prostate Cancer Screening, the large American Screening trial, Prostate, Lung, Colorectal, and Ovarian (PLCO), Princess Margaret Cancer Centre (University Health Network) and Mount Sinai Hospital (Sinai Health System) in Toronto.

By evaluating the molecular changes that occur in large cohorts of ovarian cancer patients, the researchers were able to identify several lncRNAs that are linked to the disease.

Unlike other solid tumors, there has been limited progress in understanding the contribution of genetic risk factors to the development of uveal melanoma, researchers say, primarily due to the absence of comprehensive genetic data from patients as the large sample cohorts for this rare cancer type have not been available for research.

Researchers believe it is the largest epigenetic study yet for any single cancer type and, importantly, the first to use a large cohort of primary patient tumor tissues instead of cell lines grown in the laboratory.

Surprisingly, we found the same signature in large cohorts of women without the BRCA1 mutation and it was able to predict breast cancer risk several years before diagnosis.»

In this study, researchers used blood samples collected several years before breast cancer development from two large UK cohorts of women — the MRC National Survey of Health and Development and the UK Collaborative Trial of Ovarian Cancer Screcancer development from two large UK cohorts of women — the MRC National Survey of Health and Development and the UK Collaborative Trial of Ovarian Cancer ScreCancer Screening.

The NYGC and its founding member institutions are conducting additional studies involving Watson to help accelerate the discovery of potentially actionable sequence variants in various types of cancer, including an ongoing study that involves DNA and RNA from a larger cohort of glioblastoma patients, and a study of 200 patients with different types of cancer.

Interestingly, two recent reports that have catalogued recurrent focal deletions in large cohorts of human tumors and cancer cell lines.

Background In our institute, the first research program on disseminated tumor cells (DTC) detection in the bone marrow of early breast cancer patients was initiated in the late 90's; with about a thousand patients included, we constituted one of the largest cohort ever reported and contributed to the landmark report that established bone marrow DTC as a level - of - evidence 1 prognostic factor in early breast cancer (Braun, N Engl J Med 2005In our institute, the first research program on disseminated tumor cells (DTC) detection in the bone marrow of early breast cancer patients was initiated in the late 90's; with about a thousand patients included, we constituted one of the largest cohort ever reported and contributed to the landmark report that established bone marrow DTC as a level - of - evidence 1 prognostic factor in early breast cancer (Braun, N Engl J Med 2005in the bone marrow of early breast cancer patients was initiated in the late 90's; with about a thousand patients included, we constituted one of the largest cohort ever reported and contributed to the landmark report that established bone marrow DTC as a level - of - evidence 1 prognostic factor in early breast cancer (Braun, N Engl J Med 2005in the late 90's; with about a thousand patients included, we constituted one of the largest cohort ever reported and contributed to the landmark report that established bone marrow DTC as a level - of - evidence 1 prognostic factor in early breast cancer (Braun, N Engl J Med 2005in early breast cancer (Braun, N Engl J Med 2005).

Our bioinformatics analysis, based on multiple independent large - size cohorts shows that MELK is strongly overexpessed in BBC / TNBC, not only compared to normal breast tissues, but also compared to luminal or ER / PR + breast cancer.

A study conducted in 2000 examined the relationship between the HEI and the risk of major chronic disease (cardiovascular disease and cancer), using the large cohorts in two ongoing studies at Harvard (nurses and health professionals).

Of two large cohort studies with > 35,000 participants (3,4), Sluijs et al. (3) did not observe a significant association for total protein after adjustment for BMI and waist circumference in the Dutch cohort of European Prospective Investigation into Cancer and Nutrition (EPIC)- InterAct.

Since the WCRF report, Luo et al [59] studied the association between the drinking coffee and the risk of pancreatic cancer in a large population - based cohort study in Japan and concluded there was no increased risk of pancreatic cancer with coffee intake.