COG is widely recognized as the premier collaborative research organization, having enrolled more children with
cancer on clinical trials than any other organization in the world.
Not exact matches
Freenome, a liquid biopsy startup that's looking to enter
clinical trials, is working
on technology that would be able to detect
cancer in the body, including its location and type, using only blood samples.
The striking example I focused
on then was the
cancer drug Avastin, developed by Genentech (now Roche)-- which, at the time, had been studied in at least 400 completed human
clinical trials for various
cancers.
Shares of
cancer - focused biotech Clovis Oncology soared nearly 50 % in early Monday trading
on the strength of
clinical trial results for its ovarian
cancer treatment Rubraca.
Some retrospective studies and preclinical work have indicated that it might also lower a person's risk of
cancer, though at least one
clinical trial wasn't able to show that it had any protective effect
on esophageal
cancer.
Researchers from the Sichuan University in Chengdu inserted the re-engineered cells into a lung
cancer patient participating in a
clinical trial at the West China Hospital
on October 28th, according to Nature.
It can be everything from an über - helpful call - center rep to an oncology adviser, recommending
cancer treatments
on the basis of a patient's genetic profile and thousands of
clinical trials and medical journal articles it has analyzed.
HERERA: Merck (NYSE: MRK) was one of the best performing stocks
on the blue chip Dow index today, after the drug company «s new type of lung
cancer drug performed better than expected in a highly anticipated
clinical trial.
Additional
clinical trial data later this year
on Tesaro's key drug, Niraparib, which targets advanced solid tumors in ovarian and breast
cancers, could help narrow the valuation gap, the people said.
Although a considerable body of scientific evidence substantiates the positive correlation between curcumin consumption and a reduction in the risk of
cancer, the paucity of suitably designed human
clinical trials that clearly demonstrate any direct effect of curcumin
on cancer markers may prevent Health Canada from approving a
cancer risk reduction claim for curcumin within the current regulatory framework.
Sawyers conducted some of the first, dramatically successful
clinical trials on Gleevec, which inhibits specific enzymes at play in certain
cancers, particularly CML.
Based
on results of the current study described in a report online June 18 in the journal
Cancer Cell, Johns Hopkins researchers say they are planning a phase I clinical trial to test the paclitaxel - fostamatinib combination therapy in patients with recurrent advanced ovarian c
Cancer Cell, Johns Hopkins researchers say they are planning a phase I
clinical trial to test the paclitaxel - fostamatinib combination therapy in patients with recurrent advanced ovarian
cancercancer.
«Current therapies in
clinical trials are focused
on targeting genetic changes in tumors and helping to boost one's immune system to fight the
cancer cells.
«First
clinical trial on HER -2-negative breast
cancer with nintedanib shows promising results.»
In a head - to - head
clinical trial comparing standard chemotherapy with the immunotherapy drug nivolumab, researchers found that people with squamous - non-small cell lung
cancer who received nivolumab lived,
on average, 3.2 months longer than those receiving chemotherapy.
Findings were presented at the WCLC are based
on the updated results of 12 lung
cancer patients enrolled in the
clinical trial with pembro and irinotecan or gemcitabine with or without vinorelbine or docetaxel.
As Scientific American reported earlier this year, more than half of the current
cancer clinical trials do incorporate some form of immunotherapy but still oncologists are often only in the early stages of understanding how to use such treatment
on a larger scale.
The team is now calling for a much larger
clinical trial, involving one quarter of a million women, to investigate the effect of the screening using HPV testing
on cancer rates.
Antioxidants can neutralize those effects, although
clinical trials on cancer prevention have yielded mixed results.
The German biotech CureVac, for example, has brought mRNA - based vaccines for rabies and
cancer to
clinical trials, and Karikó now heads a research team at BioNTech in Mainz, Germany, that focuses
on mRNA - based drugs.
Biden has also been talking to Los Angeles, California, oncologist and billionaire Patrick Soon - Shiong, who
on 11 January announced an industry - led moonshot aimed at testing in
clinical trials combinations of
cancer immunotherapy drugs, one of most promising new
cancer treatments in recent years.
Some Hedgehog signaling reducing agents are currently
on the market to treat specific types of
cancers while others are in
clinical trials.
Several years ago, for example, poor chemical probe data led researchers to pursue a final stage
clinical trial on a
cancer drug candidate called iniparib.
Swedish researchers have started a
clinical trial to assess whether a prostate
cancer drug could help prevent pedophilic behavior — and they're counting
on online donations to help finish it.
While it has nearly the same incidence among women as breast
cancer, there were only 16 open
clinical trials for Hashimoto's disease as of August 2015, according to a list
on clinicaltrials.gov.
More than 500
clinical trials are underway to explore the impact of these and other checkpoint inhibitors
on a dozen varieties of
cancer, alone or with other immunotherapies, as well as conventional treatments.
In 1996, when RMP - 7 was first used
on brain
cancer patients in a Phase 1
clinical trial at UCLA, it was found to be safe, with virtually no side effects.
On its own, DON has shrunk tumors in
clinical trials of people with a variety of advanced
cancers, but its damage to the gastrointestinal system, a glutton for glutamine, ultimately proved too toxic for humans, say the scientists.
Dr. Sparano continued: «This is the first prospectively conducted
clinical trial evaluating this assay — or any multigene expression assay for that matter — in which patients with early stage breast
cancer were uniformly treated based
on their assay results.
«Part of what was exciting about the design of this
clinical trial is that we decided early
on to accept women from a younger and generally sicker population than is typically enrolled in
clinical trials,» says Dr. Cristofanilli, who is also a researcher at the Sidney Kimmel
Cancer Center at Thomas Jefferson University.
White and colleagues will work with other collaborators at the
Cancer Institute to develop early - phase patient
clinical trials based
on the findings from this study in the near future.
Cantley hopes to soon start
clinical trials that will select
cancer patients based
on KRAS or BRAF mutations and possibly GLUT1 status.
Professor John Simes, Director of the NHMRC
Clinical Trials Centre, University of Sydney, who over-saw the
trial conduct said «This is an excellent example of ensuring patients will receive optimal care for their
cancer based
on a well conducted
trial.
Partnering with the U.S. Food and Drug Administration allowed Doebele and colleagues to access
clinical trial data describing initial tumor response, PFS and OS for 305 patients with stage IIIb or IV non-small cell lung
cancer on trials of ALK inhibitors and 355 similar patients
on trials of immunotherapies directed at PD - 1.
Westin would «do a fantastic job [in Congress], but he's grossly overqualified for what goes
on in Washington, [D.C.,]» says R. Eric Davis, an associate professor at MD Anderson who partners with Westin
on cancer clinical trials.
«Randomized Controlled Pilot
Trial of Mindfulness - based Stress Reduction for Breast and Colorectal Cancer Survivors: Effects on Cancer - related Cognitive Impairment,» published online in advance of print in the Journal of Cancer Survivorship, is the first randomized clinical trial to evaluate the effects of mindfulness - based stress reduction, known as MBSR, on fatigued breast and colorectal cancer survivors, the majority of whom had been treated with chemothe
Trial of Mindfulness - based Stress Reduction for Breast and Colorectal
Cancer Survivors: Effects on Cancer - related Cognitive Impairment,» published online in advance of print in the Journal of Cancer Survivorship, is the first randomized clinical trial to evaluate the effects of mindfulness - based stress reduction, known as MBSR, on fatigued breast and colorectal cancer survivors, the majority of whom had been treated with chemoth
Cancer Survivors: Effects
on Cancer - related Cognitive Impairment,» published online in advance of print in the Journal of Cancer Survivorship, is the first randomized clinical trial to evaluate the effects of mindfulness - based stress reduction, known as MBSR, on fatigued breast and colorectal cancer survivors, the majority of whom had been treated with chemoth
Cancer - related Cognitive Impairment,» published online in advance of print in the Journal of
Cancer Survivorship, is the first randomized clinical trial to evaluate the effects of mindfulness - based stress reduction, known as MBSR, on fatigued breast and colorectal cancer survivors, the majority of whom had been treated with chemoth
Cancer Survivorship, is the first randomized
clinical trial to evaluate the effects of mindfulness - based stress reduction, known as MBSR, on fatigued breast and colorectal cancer survivors, the majority of whom had been treated with chemothe
trial to evaluate the effects of mindfulness - based stress reduction, known as MBSR,
on fatigued breast and colorectal
cancer survivors, the majority of whom had been treated with chemoth
cancer survivors, the majority of whom had been treated with chemotherapy.
Duke University has suspended three
cancer clinical trials in response to allegations that a key researcher
on the studies embellished his resumé.
«That there are a number of
clinical trials on - going in a range of different
cancers is an encouraging start.»
The patients were enrolled in
clinical trials sponsored by St. Jude or the Children's Oncology Group, an international
clinical trials group focused exclusively
on pediatric
cancer.
Gemcitabine is used
on bladder, pancreas and ovary
cancer, whilst DON has been tested in
clinical trials.
The Johns Hopkins team tested ImmunoMap's ability to correlate immune responses
on receptor sequencing data from T - cells in the tumors of 34 patients with
cancer enrolled in a nationwide
clinical trial of the immunotherapy drug nivolumab.
In fact, researchers at Stanford are already collaborating
on initial
clinical trials of an antibody that blocks
cancer cells from displaying one such death - evading signal — a molecule called CD47.
One report, focusing
on clinical trial patients with advanced kidney
cancer treated with checkpoint inhibitors, is from scientists at Dana - Farber Cancer Institute and the Broad Institute of MIT and Harvard, led by Eliezer Van Allen, MD, of Dana - Farber and the Broad, and Toni Choueiri, MD, director of the Lank Center for Genitourinary Oncology at Dana - F
cancer treated with checkpoint inhibitors, is from scientists at Dana - Farber
Cancer Institute and the Broad Institute of MIT and Harvard, led by Eliezer Van Allen, MD, of Dana - Farber and the Broad, and Toni Choueiri, MD, director of the Lank Center for Genitourinary Oncology at Dana - F
Cancer Institute and the Broad Institute of MIT and Harvard, led by Eliezer Van Allen, MD, of Dana - Farber and the Broad, and Toni Choueiri, MD, director of the Lank Center for Genitourinary Oncology at Dana - Farber.
The study, a retrospective survival analysis, included 229 patients who participated in two randomized, controlled
clinical trials focused
on relief of constipation for patients receiving palliative care for various types of late - stage
cancer and other terminal diseases.
The USPSTF based its recommendations
on a meta - analysis of 136
clinical trials, observational studies and a systematic review evaluating the effects of supplementation
on fracture and
cancer risk.
Currently, a genomic analysis
clinical trial at the
Cancer Institute is focused
on those patients with rare or poor - prognosis
cancers, including pediatric patients.
There were 595 participants in the G6
clinical trial, and information
on the presence or absence of PIK3CA gene mutations was available for 512,240 with HER2 - postive breast
cancer and 272 with triple - negative breast
cancer.
Effect of robotic - assisted vs conventional laparoscopic surgery
on risk of conversion to open laparotomy among patients undergoing resection for rectal
cancer: the ROLARR randomized
clinical trial.
NCCC's leading pancreatic
cancer research experts highlight groundbreaking research projects and
clinical trials underway for this challenging
cancer, and offer thoughts
on what the future holds.
OSR Grants and Contracts Officers works collaboratively with the Lombardi Comprehensive
Cancer Center (LCCC)
Clinical Research Management Office (CRMO) on LCCC clinical trial contract and budget negotiation, including spending account and sub-sit
Clinical Research Management Office (CRMO)
on LCCC
clinical trial contract and budget negotiation, including spending account and sub-sit
clinical trial contract and budget negotiation, including spending account and sub-site setup.