Even before treatment,
cancer patients in the study had a small number of infection - and tumor - fighting T cells that target these unusual proteins, the researchers found.
Not exact matches
A series of preliminary Mayo Clinic
studies conducted
in 2010 showed promise for the potential use of a chemical component of green tea (epigallocatechin gallate)
in reducing the number of
cancer cells
in patients with chronic lymphocytic leukemia.
FITBIT DATA AIDS RESEARCHERS
IN UNDERSTANDING SURGERY RECOVERY: Fitbit data can help researchers and doctors predict the risk of 30 - and 60 - day readmission after surgery for cancer patients, according to a study published in the Annals of Behavioral Medicin
IN UNDERSTANDING SURGERY RECOVERY: Fitbit data can help researchers and doctors predict the risk of 30 - and 60 - day readmission after surgery for
cancer patients, according to a
study published
in the Annals of Behavioral Medicin
in the Annals of Behavioral Medicine.
The company points to a simple resource allocation problem that's hindered the most effective
patient care: the fact that it is physically impossible for oncologists to keep track of every
study, every clinical trial, and every breakthrough
in the wildly stratified world of
cancer research.
A new
study using lab - engineered microtumors allowed doctors to better predict if a
cancer drug treatment will work
in a
patient.
Speaking of checkpoint inhibitor drugs... Merck's star
cancer immunotherapy treatment Keytruda is facing some troubling clinical trial incidents which have now compelled the Food and Drug Administration (FDA) to halt three
studies of the drug
in multiple myeloma, a rare blood
cancer, after a number of
patient deaths.
The first step
in the process is to surgically remove the
patient's tumor and ensure that the
patient is
cancer free by confirming that there is no sign of
cancer on blood tests and imaging
studies.
Besides randomized controlled clinical trials, there are a number of ways researchers can
study how a particular
cancer treatment is playing out
in the real world: there are retrospective
studies, observational
studies, and even prospective research done using
patient registries.
The
study, just published
in Science, showed that the creation of what the researchers are calling microtumors can help predict drug effectiveness
in cancer patients better than the current standard method of testing the drugs on rodents.
Other
studies, meanwhile, are examining tryp's potential efficacy as an antifungal agent; and as a prognostic indicator
in patients with brain
cancer (as seen by increased uptake of the amino acid on a PET scan).
«While we are disappointed CheckMate - 026 did not meet its primary endpoint
in this broad
patient population, we remain committed to improving
patient outcomes through our comprehensive development program, including the ongoing Phase III CheckMate - 227
study exploring the potential of the combination of Opdivo plus [our other
cancer immunotherapy] Yervoy for PD - L1 positive
patients, and Opdivo plus Yervoy, or Opdivo plus chemotherapy
in PD - L1 negative
patients,» he added.
April 16 Merck & Co's immunotherapy Keytruda plus chemotherapy significantly improved overall survival versus chemotherapy alone
in newly - diagnosed
patients with advanced non-small cell lung
cancer in a highly - anticipated
study that appears to cement the company's lead
in the most lucrative oncology market.
The biotech specialist said that its updated phase 2 data
in a
study of its poziotinib candidate treatment for non-small cell lung
cancer resulted
in a preliminary confirmed objective response rate and potential progression - free survival benefit
in patients with the EGFR Exon 20 Mutant form of the disease.
A randomized, blinded
study of the impact of intercessory prayer on spiritual well - being
in patients with
cancer.
A recent research
study conducted by the Sahlgrenska Academy at University of Gothenburg
in Gothenburg, Sweden,
in collaboration with DuPont Nutrition & Health (DuPont), yielded breakthrough results demonstrating that probiotic intervention can alter and modify intestinal microbiota
in patients with colon
cancer.
It does not include medical information, apart from for
cancer patients or those participating
in studies.
«While the small - scale
study suggests that beta - blockers may reduce the risk of breast
cancer returning, more research is needed
in this area to determine the effectiveness and safety of the treatment before it can be routinely offered to breast
cancer patients.
Taub, who cut a deal with the feds to avoid prosecution, then testified that starting
in 2003, he steered between 25 and 50
cancer patients to Silver for legal representation so Taub could secure taxpayer money to
study asbestos - related illness.
According to a report from the National
Cancer Institute, a
study of 30 randomized
studies found that THC (the active ingredient
in marijuana) extracts outperformed traditional anti-nausea drugs and helped
patients gain weight.
In the first study evaluating patient - reported cosmetic outcomes in a population - based cohort of older women with breast cancer, The University of Texas MD Anderson Cancer Center researchers found that less radiation was associated with improved cosmetic satisfaction long - ter
In the first
study evaluating
patient - reported cosmetic outcomes
in a population - based cohort of older women with breast cancer, The University of Texas MD Anderson Cancer Center researchers found that less radiation was associated with improved cosmetic satisfaction long - ter
in a population - based cohort of older women with breast
cancer, The University of Texas MD Anderson Cancer Center researchers found that less radiation was associated with improved cosmetic satisfaction long -
cancer, The University of Texas MD Anderson
Cancer Center researchers found that less radiation was associated with improved cosmetic satisfaction long -
Cancer Center researchers found that less radiation was associated with improved cosmetic satisfaction long - term.
Prior
studies have shown that
cancer patients had high levels of DNA fragments
in their blood.
During this
in depth
study, an international team of researchers led by British scientists investigated the impact of anti-hormone therapy on samples taken from
patients with prostate
cancer.
Researchers at the Icahn School of Medicine at Mount Sinai have created the first mathematical model that can predict how a
cancer patient will benefit from certain immunotherapies, according to a
study published
in Nature.
That
study showed how a similar model can be used to understand immune response
in patients with pancreatic
cancer who survive longer than others.
The
study has been tested
in metastatic
patients with different primary tumours such as breast, colon and lung
cancer.
A raft of
studies in laboratory animals, molecular models and
cancer patients suggest that pain drugs given during and after
cancer surgery stimulate the growth and spread of certain tumors.
«One of the toughest challenges of lung
cancer is what to do for
patients when the
cancer comes back
in an area that's been treated previously with radiation treatment,» said James J. Urbanic, M.D., lead author of the
studies and a radiation oncologist at Wake Forest Baptist.
A dozen human
studies of MDMA, LSD, a powerful African drug called ibogaine and psilocybin, from so - called «magic mushrooms,» are now under way, testing the once - stigmatized drugs as treatments for not only PTSD, but also cluster headaches and addiction, as well as anxiety and depression
in cancer patients.
A new
study has identified a group of molecules
in prostate -
cancer cells that doctors might one day use to distinguish which
patients should be treated with radiation therapy if rising PSA levels indicate their
cancer has recurred after surgical removal of the prostate.
Based on results of the current
study described
in a report online June 18
in the journal
Cancer Cell, Johns Hopkins researchers say they are planning a phase I clinical trial to test the paclitaxel - fostamatinib combination therapy in patients with recurrent advanced ovarian c
Cancer Cell, Johns Hopkins researchers say they are planning a phase I clinical trial to test the paclitaxel - fostamatinib combination therapy
in patients with recurrent advanced ovarian
cancercancer.
Past
studies have found IDH mutations to be among the most common genetic differences seen
in patients with iCCA, but how they contribute to
cancer development was unknown going into the current effort.
In a study featured in the December issue of The Journal of Nuclear Medicine, Australian researchers demonstrate that PET scans can identify which of these prostate cancer patients would benefit from salvage radiation treatment (SRT
In a
study featured
in the December issue of The Journal of Nuclear Medicine, Australian researchers demonstrate that PET scans can identify which of these prostate cancer patients would benefit from salvage radiation treatment (SRT
in the December issue of The Journal of Nuclear Medicine, Australian researchers demonstrate that PET scans can identify which of these prostate
cancer patients would benefit from salvage radiation treatment (SRT).
Half of the
patients treated
in this
study responded to either ponatinib (typically used for certain types of leukemia) or pazopinib (a kidney
cancer drug), depending on the genetic alterations identified through sequencing.
While further
study of larger
patient groups with longer follow - up times is needed for this cohort of prostate
cancer patients, this
study is pivotal
in providing evidence for change
in practice.»
These genetic mutations can fluctuate over time, and some
patients can harbor more than one mutation,» said Zofia Piotrowska, MD, lead author of the
study and a thoracic oncologist at the Massachusetts General Hospital
Cancer Center
in Boston.
In a recent study, working with a team of researchers, Danino demonstrated that bacteria in pancreatic tumors degrade a chemotherapy drug — Gemcitabine — most commonly used to treat patients who have pancreatic cance
In a recent
study, working with a team of researchers, Danino demonstrated that bacteria
in pancreatic tumors degrade a chemotherapy drug — Gemcitabine — most commonly used to treat patients who have pancreatic cance
in pancreatic tumors degrade a chemotherapy drug — Gemcitabine — most commonly used to treat
patients who have pancreatic
cancer.
By taking a high - cost drug with a low - fat meal — instead of on an empty stomach, as prescribed — prostate
cancer patients could decrease their daily dose, prevent digestive issues and cut costs by 75 percent, according to a new
study in the March 28, 2018, issue of the Journal of Clinical Oncology (JCO).
Results from a 2006
study in Ireland and the U.S. suggest that
patients who undergo surgery to remove breast or prostate
cancer might be less prone to recurrence if they are administered regional anesthesia during their procedures, rather than general anesthesia alone.
The idea to specifically
study this group of
patients was based on groundbreaking research Garon published
in the New England Journal of Medicine last year, which found that among
patients who received pembrolizumab, those with PD - L1 expression on at least 50 percent of their
cancer cells showed the longest survival and disease control.
Led by researchers at the Ohio State University Comprehensive
Cancer Center — Arthur G. James
Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James), the retrospective
study suggested that a pattern of molecules called microRNA (miRNA)
in tumor cells might predict
patients» response to radiation therapy.
Vitamin C has previously been shown to be effective as a non-toxic anti-
cancer agent
in studies by Nobel Prize winner Linus Pauling and was recently shown to reduce mortality by 25 % on breast
cancer patients in Japan.
Now a University of Colorado
Cancer Center study published online ahead of print in the journal Oncogene offers compelling evidence explaining this failure and offering a possible strategy for the use of retinoic acid or other retinoids against some breast cancers: Because early clinical trials are often offered to patients who have already tried other more established therapies, breast cancer cells may have been pushed past an important tipping point that offers retinoic acid resis
Cancer Center
study published online ahead of print
in the journal Oncogene offers compelling evidence explaining this failure and offering a possible strategy for the use of retinoic acid or other retinoids against some breast
cancers: Because early clinical trials are often offered to
patients who have already tried other more established therapies, breast
cancer cells may have been pushed past an important tipping point that offers retinoic acid resis
cancer cells may have been pushed past an important tipping point that offers retinoic acid resistance.
The
study also suggests that targeting the machinery that makes cells mobile, rather than targeting the tissue - clearing process — which has been tested
in patients but has not been very effective — may be a better treatment strategy to stop
cancers from spreading.
The
study, was reported Feb 13 to the 5th International Conference on Innovative Approaches
in Head and Neck Oncology (ICHNO) will reduce significantly the number of HNSCC
patients who currently undergo selective neck dissection (SND), a procedure which involves removing a group of lymph nodes from the neck
in order to try to eradicate those which may have been reached by the
cancer.
The
study, sponsored by Merrimack Pharmaceuticals, evaluated 417
patients enrolled at more than 100 sites
in North America, South America, Europe, Asia and Australia, including
patients at the Virginia G. Piper
Cancer Center at Scottsdale Healthcare.
«Our
study demonstrates that there is a much higher risk of pancreatic
cancer in patients with acute pancreatitis than commonly believed,» Agarwal said.
According to Dr. Gass, «
In an era where we see more early - staged breast
cancer patients choosing mastectomy, no
study has previously addressed breast specific sensuality, defined as the breast's role during intimacy.
«Data from this
study serves as rationale to now include dogs with spontaneous
cancers in the advancement and optimization of PMed for human
patients,» according to the
study, Prospective molecular profiling of canine
cancers provides a clinically relevant comparative model for evaluating personalized medicine (PMed) trials.
«This
study demonstrates the value of using the SEER database to analyze factors associated with surgery as a treatment for localized pancreatic
cancer in a large number of patients over a prolonged period of time,» says Dr. Kim, who is also Chief Medical Officer of UH Seidman Cancer Center and the Charles Hubay Professor at Case Western Reserve School of Med
cancer in a large number of
patients over a prolonged period of time,» says Dr. Kim, who is also Chief Medical Officer of UH Seidman
Cancer Center and the Charles Hubay Professor at Case Western Reserve School of Med
Cancer Center and the Charles Hubay Professor at Case Western Reserve School of Medicine.
Researchers at Moffitt
Cancer Center hope to improve NSCLC
patient survival with the results of a
study that found that inherited genetic variations
in interleukin genes are associated with improved
patient survival and response to therapy.