Sentences with phrase «cancer sequencing effort»

Fifteen teams analyzed nearly 500 patients» tumors for genetic aberrations and sequenced the protein - coding DNA of 316 samples — by far the largest cancer sequencing effort to date.

Large - scale cancer sequencing efforts such as TCGA and ICGC have catalogued somatic mutations in a variety of common cancer types.

Now comes a second part of the study, something that sets it apart from other cancer sequencing efforts.

Not exact matches

It will focus its initial clinical sequencing efforts on cancer, teaming up with the Moores Cancer Center at the University of California, San Diego to sequence the genomes of every patient who is treated there, as well as perform a full genome sequence on their tcancer, teaming up with the Moores Cancer Center at the University of California, San Diego to sequence the genomes of every patient who is treated there, as well as perform a full genome sequence on their tCancer Center at the University of California, San Diego to sequence the genomes of every patient who is treated there, as well as perform a full genome sequence on their tumors.

The 15 AACR scientists, who were already in Washington, D.C., to meet with the U.S. Food and Drug Administration on genetic testing for cancer patients, tossed around ideas including expanding NCI's tumor genome - sequencing efforts and getting the government to cover the costs of genomic tumor profiling.

The convergence of several factors explains the trend: cheaper genetic sequencing technologies, the discovery of new oncogenes (genes that can cause a normal cell to become cancerous), a new generation of computers and bioinformatics that can analyze vast amounts of data, and a multibillion - dollar effort by researchers inside and outside the pharma industry to develop targeted drugs and companion diagnostics for cancer.

It has launched projects such as a major effort to develop knock - out mice (ScienceNOW, 7 September 2006) and The Cancer Genome Atlas (Science, 16 December 2005, p. 1751), which, with the cancer institute, is sequencing mutations in human caCancer Genome Atlas (Science, 16 December 2005, p. 1751), which, with the cancer institute, is sequencing mutations in human cacancer institute, is sequencing mutations in human cancers.

In 2012, as part of efforts to better understand the causes of melanoma, researchers at the Broad Institute, the Dana - Farber Cancer Institute and a number of other institutes reported the results of whole genome sequencing of 25 human metastatic melanomas (Berger et al., 2012).

Also today, NHGRI and the National Cancer Institute (NCI), both part of the National Institutes of Health (NIH), announced that all three sequencing centers will devote a significant part of their efforts to The Cancer Genome Atlas (TCGA) Pilot Project, which is testing the feasibility of a large - scale, systematic approach to identify important genomic changes involved in cCancer Institute (NCI), both part of the National Institutes of Health (NIH), announced that all three sequencing centers will devote a significant part of their efforts to The Cancer Genome Atlas (TCGA) Pilot Project, which is testing the feasibility of a large - scale, systematic approach to identify important genomic changes involved in cCancer Genome Atlas (TCGA) Pilot Project, which is testing the feasibility of a large - scale, systematic approach to identify important genomic changes involved in cancercancer.

Thanks to the Segals» gift, the pancreatic - cancer effort will sequence the genomes of tumors from up to 225 patients from the University of Chicago Medicine - NorthShore University HealthSystem pancreatic cancer program over the next three years.

Her translational research efforts devise sequencing - based diagnostics, decision - support tools and databases, and the use of genomics to evaluate immunity - related aspects of cancers.

Large - scale sequencing efforts like the 1,000 Genomes Project and The Cancer Genome Atlas now consider BAM the standard format for data exchange.

In it, the authors review bioinformatics approaches for evaluating single - base substitutions in both coding and noncoding regions, with an emphasis on large cancer resequencing efforts including the Tumor Sequencing Project, the Cancer Genome Atlas (TCGA), and the AML1 cancer gcancer resequencing efforts including the Tumor Sequencing Project, the Cancer Genome Atlas (TCGA), and the AML1 cancer gCancer Genome Atlas (TCGA), and the AML1 cancer gcancer genome.

Topics that will be explored include: • Cellular and developmental origins of pediatric cancer • Key findings of pan-cancer analysis efforts • Computational pipelines to analyze large - scale sequencing data • Opportunities for leveraging existing cancer genomics datasets • Strategies for integrative analysis of germline and somatic variants • Correlation of germline / somatic variation to clinical features such as tumor subtype.

TCGA, launched in 2005, is a comprehensive and coordinated effort to accelerate the understanding of the molecular basis of cancer through the application of genome analysis technologies, including large - scale genome sequencing.

The Sequencing and ncRNA Program (ncRNA core), led by Chang - Gong Liu, Ph.D., is a shared resource established in 2009 to support ncRNA cancer research efforts at MD Anderson Cancer Center and Institutions under the UT scancer research efforts at MD Anderson Cancer Center and Institutions under the UT sCancer Center and Institutions under the UT system.

He directs a Genome Data Analysis Center as part of The Cancer Genome Atlas (TCGA) project, a comprehensive and coordinated effort to accelerate our understanding of the molecular basis of cancer through the application of genome analysis technologies, including large - scale genome sequeCancer Genome Atlas (TCGA) project, a comprehensive and coordinated effort to accelerate our understanding of the molecular basis of cancer through the application of genome analysis technologies, including large - scale genome sequecancer through the application of genome analysis technologies, including large - scale genome sequencing.