The genTrue hereditary
cancer test identifies those who have suspected heritable cancer syndrome.
Not exact matches
The genomic
tests can quickly
identify those who need further attention and reassure those who
test negative for the
cancer.
If you have a strong family history of breast
cancer or other
cancers, your doctor may recommend a blood
test to help
identify specific mutations in BRCA or other genes that are being passed through your family.
With new
tests to
identify women who are at heightened risk of breast
cancer, new drugs aimed at preventing allergies, and the discovery of new genes that are key to the progression of conditions like Alzheimer's - to give just three examples - we are at the dawn of a whole new era:
«Also, performing a yearly fecal immunochemical
test («FIT») is an effective screening method to
identify those who need further evaluation and possible treatment to prevent the progression of colorectal
cancer.»
«How melanoma tumors form: Team
identifies drugs that halt skin
cancer metastasis in lab
tests.»
However, a blood
test could be used as a first line of defense to
identify patients with warning signs of
cancer; these high - risk patients could then be referred for a colonoscopy to learn more.
«Starting with our cell model that mimics human pancreatic
cancer progression, we
identified released proteins, then
tested and validated a subset of these proteins as potential plasma biomarkers of this
cancer,» Zaret said.
Up until now, no single
test could predict the severity of the
cancer type - the current PSA
test (Kallikrein 3), which is located near Kallikrein 6, only
identifies the risk of prostate
cancer, not the severity.
A blood
test for colon
cancer will never replace colonoscopy: once polyps are
identified, a colonoscopy is still the best way to figure out where they're located so that they can be removed.
This new study demonstrated that the
test can also be used to
identify people with precancerous polyps — a finding that makes it potentially more useful for a screening
test, since it may be able to
identify cancer risk before the disease actually develops.
Scientists have developed a new
test to
identify patients who are at risk of suffering a relapse from testicular
cancer.
«A large, recently published study examined the performance of a multitarget stool
test that
identifies several DNA abnormalities associated with colorectal
cancer or precancerous adenomas.
Screening histories preceding cervical
cancers (n = 623) and precancers (n = 5,369) were examined to assess the relative contribution of the Pap
test and HPV
test components in
identifying cases.
The analysis found that HPV
testing identified more women subsequently diagnosed with
cancer and precancer than the Pap
test.
A report in The Journal of Molecular Diagnostics describes a new blood
test that can accurately and quickly
identify genetic mutations associated with NSCLC, allowing clinicians to make earlier, individualized treatment choices — a step forward in personalized
cancer treatment.
The commission concludes that the tumours likely to result from the
tests — such as thyroid or brain
cancer — either can not be
identified by screening or can not be treated.
«We hope that our
test will significantly improve the odds of survival of breast
cancer patients by allowing doctors to
identify the most effective but least toxic form of chemotherapy for each individual patient before the treatment begins.»
Exploiting the same pre-clinical model used for their studies, the researchers are
testing the efficacy of this kind of drug candidates against
cancer stem cells, and the possibility of
identifying combination regimens with standard chemotherapies with minimized toxic effects, with the perspective of their possible application for the treatment of human breast
cancer.
«We have effective screening
tests for several
cancers, which allow physicians and other health - care providers to
identify the disease at an earlier stage — often before symptoms surface — when treatment is more likely to result in a cure,» said senior author of the report and IPHI Director Kenneth W. Kizer.
Pap
tests can
identify cervical precancer before it turns into
cancer.
When
tested on various
cancer patient databases, iCAGES was found to be superior to other computational tools at predicting
cancer drivers from personal genomes and at
identifying beneficial treatment.
«Breath temperature
test could
identify lung
cancer.»
Mutations in known breast
cancer genes such as BRCA1 and BRCA2 are
identified in only approximately 20 per cent of women who are offered genetic
testing for familial breast
cancer.
The
test, which analyzes fluid from pancreatic cysts, can
identify a common type of benign cyst that can't be differentiated by imaging alone from cysts that may progress to pancreatic
cancer.
Scientists at the University of Exeter Medical School found that one in 60 people over the age of 60 who had invisible blood in their urine (
identified by their GP
testing their urine) transpired to have bladder
cancer.
Tested on data from The
Cancer Genome Atlas (TCGA), MEGENA
identified novel regulatory targets in breast and lung
cancers, outperforming other co-expression analysis methods.
The specificity of the
testing strategy was 99.9 percent, meaning that only 0.1 percent of patients without
cancer would be falsely
identified as having the disease.
The AGA recommendation for tumor
testing in all newly diagnosed cases of colorectal
cancer to
identify Lynch syndrome could be considered as a process measure to ensure that patients are receiving the highest quality of care.»
Rather than simply
identifying a
cancer by location or tissue type, researchers now use advanced molecular profiling
tests to characterize tumors, the proteins they express and the novel mutations they develop — known as neoantigens.
Researchers at The Johns Hopkins Kimmel
Cancer Center have developed a
test for urine, gathered during a routine procedure, to detect DNA mutations
identified with urothelial
cancers.
Women with particularly aggressive forms of breast
cancer could be
identified by a
test that predicts whether the disease is likely to spread to the brain.
The researchers used a technique called «mutation tracking» — developing a digital PCR
test that was personalised to the mutations found in an individual patient's
cancer — to
identify tumour DNA in the bloodstream.
More than 1800 compounds have been
identified in human breath, and
tests are being developed for diabetes,
cancer, and other afflictions.
Importantly, the research team, funded by
Cancer Research UK and the Medical Research Council, have also developed a biomarker test to identify SETD2 mutated tumors, something that can be used immediately in cancer diag
Cancer Research UK and the Medical Research Council, have also developed a biomarker
test to
identify SETD2 mutated tumors, something that can be used immediately in
cancer diag
cancer diagnosis.
For patients with difficult - to - treat
cancers, doctors increasingly rely on genomic
testing of tumors to
identify errors in the DNA that indicate a tumor can be targeted by existing therapies.
Dr Chris Parker, Chair of the NCRI's Prostate
Cancer Clinical Studies Group, said: «There's a need to develop better tests to identify and monitor men with aggressive prostate c
Cancer Clinical Studies Group, said: «There's a need to develop better
tests to
identify and monitor men with aggressive prostate
cancercancer.
The difference with Xalkori is that a
test exists to
identify that slim percentage of lung
cancer patients (about 8,000 people in the United States and 40,000 worldwide each year) who would respond well.
Fortunately, the mutation occurs early in the life of the
cancer, so
tests like a serum developed by Panacea Pharmaceuticals in Japan may help
identify a target early on.
«Once
identified, we further
tested their role as
cancer drivers, for example by looking at molecules with and without mutations and comparing their structure and function,» he adds.
«CD1D performed much better than any other pancreatic secretion marker previously
tested in
identifying pancreatic
cancer,» Dr. Raimondo says.
Professor Widschwendter says: «The data is encouraging since it shows the potential of a blood based epigenetic
test to
identify breast
cancer risk in women without known predisposing genetic mutations.»
Objective To
identify common genetic markers that may confer differential benefit from aspirin or NSAID chemoprevention, we
tested gene × environment interactions between regular use of aspirin and / or NSAIDs and single - nucleotide polymorphisms (SNPs) in relation to risk of colorectal
cancer.
«If we can
identify similar genetic loci in people, and if we could find biomarkers for these gene - environment interactions, then perhaps we could develop a simple blood
test that
identifies people who are at high risk of
cancer from low - dose radiation,» says Mao.
Houston Methodist researchers led by Dario Marchetti, PhD, have developed a blood
test that can
identify circulating tumor cells to predict breast
cancer patients at risk for developing brain metastasis.
Professor Paul Pharoah, professor of
cancer epidemiology at the Cancer Research UK Cambridge Institute, said: «Our work has found a valuable piece of the puzzle behind ovarian cancer and we hope that our work could eventually form the basis of a genetic test to identify women at greatest
cancer epidemiology at the
Cancer Research UK Cambridge Institute, said: «Our work has found a valuable piece of the puzzle behind ovarian cancer and we hope that our work could eventually form the basis of a genetic test to identify women at greatest
Cancer Research UK Cambridge Institute, said: «Our work has found a valuable piece of the puzzle behind ovarian
cancer and we hope that our work could eventually form the basis of a genetic test to identify women at greatest
cancer and we hope that our work could eventually form the basis of a genetic
test to
identify women at greatest risk.
The findings also suggest that
testing levels of microRNA 135b could help
identify patients likely to develop aggressive bowel
cancer, and who might need the most intensive treatment.
Testing for these variants combined with all 21 previously
identified using genetic sequencing
identified men with a 10-fold higher risk of testicular
cancer than the population average.
Also today, NHGRI and the National
Cancer Institute (NCI), both part of the National Institutes of Health (NIH), announced that all three sequencing centers will devote a significant part of their efforts to The Cancer Genome Atlas (TCGA) Pilot Project, which is testing the feasibility of a large - scale, systematic approach to identify important genomic changes involved in c
Cancer Institute (NCI), both part of the National Institutes of Health (NIH), announced that all three sequencing centers will devote a significant part of their efforts to The
Cancer Genome Atlas (TCGA) Pilot Project, which is testing the feasibility of a large - scale, systematic approach to identify important genomic changes involved in c
Cancer Genome Atlas (TCGA) Pilot Project, which is
testing the feasibility of a large - scale, systematic approach to
identify important genomic changes involved in
cancercancer.
This personalized medicine approach may be further enhanced by molecular or genetic
testing of your
cancer, which can help
identify treatments that are more effective and / or less toxic.