Sentences with phrase «cancer therapeutic agents»
We review progress with the receptor tyrosine kinases (growth factor receptors EGFR, VEGFR, and FGFR) and nonreceptor tyrosine kinases (Bcr - Abl), where advances have been made with cancer therapeutic agents such as Herceptin and Gleevec.
http://science.sciencemag.org/
After a successful postdoc at the Ontario Cancer Institute, where he developed a proprietary platform for the discovery of novel cancer therapeutic agents, Bray was asked to join the former Amgen Research Institute in Toronto (now called the Advanced Medical Discovery Institute and no longer part of the parent company) as the head of their quantitative biology group and act as liaison to Amgen Inc. in California.
Not exact matches
A 1971 research report listed 14 references where chile was cited as a therapeutic agent for cancer.
Clinicians are currently worried that breast cancer patients with low or absent BRCA1 may become resistant to therapeutic agents such as Olaparib.
A new potential therapeutic agent, diphenyleneiodonium chloride (DPI), effectively switches off cancer stem cells, preventing their proliferation, researchers report.
The study, called «Molecular Determinants of Drug - Specific Sensitivity for Epidermal Growth Factor Receptor (EGFR) Exon 19 and 20 Mutants in Non-Small Cell Lung Cancer,» and published online in the journal Oncotarget, demonstrates how computer modeling of EGFR mutations found in lung cancer can elucidate their molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat patCancer,» and published online in the journal Oncotarget, demonstrates how computer modeling of EGFR mutations found in lung cancer can elucidate their molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat patcancer can elucidate their molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat patients.
A team led by Fengzhi Li, PhD, and Xinjiang Wang, PhD, of Roswell Park Cancer Institute (RPCI) has reported new findings regarding therapeutic targets of the novel anticancer agent FL118.
«New insights into the biology of heart failure are desperately needed to prompt new types of targeted therapeutic agents,» says senior study author James Bradner of the Dana - Farber Cancer Institute and Harvard Medical School.
The cancer researchers also found that PAK is still active, when cancer cells have already been treated with the current standard therapeutic agent Imatinib.
The Vanderbilt findings provide «proof - of - concept that targeting an antitumor agent to an intracellular protein may increase antitumor selectivity and improve the therapeutic window for treating naturally occurring cancers,» said first author Jashim Uddin, Ph.D., research associate professor of Biochemistry.
Southern Research has been awarded a new, five - year Indefinite - Delivery Indefinite - Quantity (IDIQ) contract from the National Cancer Institute to investigate the pharmacokinetic properties of antitumor and other therapeutic agents of interest -LSB-...]
It is unlikely that one  therapeutic agent will be able to target the cancer stem cells in for example all types brain tumors.
Since the discovery that telomerase is repressed in most normal human somatic cells but strongly expressed in most human tumors, telomerase has become a target for therapeutic agents to combat human cancer.