Sentences with phrase «cancer tumour cells»

Research has discovered that a compound in parsley could prevent the growth of specific breast cancer tumour cells.

Not exact matches

When placed at the site of a cancerous tumour in a rodent and «activated» by a scope with a light source, the compounds eradicated up to 100 % of cancer cells.

Also, why do cancer cells transplanted into healthy organs often not develop into tumours.

There is evidence to suggest that cancer cells are softer than normal cells (although tumours are stiffer).

This implies that cancer genes, and the mechanisms that allow tumour cells to evade apoptosis, «have deep evolutionary roots».

«This phase III trial will be noteworthy for being the first prostate cancer trial to assess a biomarker, namely AR - V7 in circulating tumour cells, as a predictor of response at the same time as testing the efficacy of the drug,» Prof Taplin will conclude.

PTEN is known as a tumour suppressor gene meaning that it typically slows the growth of cells and its loss can lead to cancer.

Injections of killed stem cells, designed to help the immune system recognise cancers, have been found to protect mice from developing tumours

In addition, Natalia Martin - Orozco at the MD Anderson Cancer Center in Houston, Texas, and her colleagues noticed Th17 cells infiltrating cancerous tumours.

The suggestion is that a small number of such cells within tumours may be the precursors to the other cancer cells in those tumours.

In a revolutionary first, Cancer Research UK - funded scientists will test whether the Zika virus can destroy brain tumour cells, potentially leading to new treatments for one of the hardest to treat cancers.

TO KILL a tumour, go after its neighbours: it seems to be the tumour - free tissue surrounding colon tumours that fosters the cancer's most pernicious cells.

Jeffrey Settleman of the Massachusetts General Hospital Cancer Center in Charlestown and his colleagues treated tumour cells with cancer Cancer Center in Charlestown and his colleagues treated tumour cells with cancer cancer drugs.

Molecular characterization of the cells that undergo cell fate transition upon oncogenic Pik3ca expression demonstrated a profound oncogene - induced reprogramming of these newly formed cells and identified gene expression signatures, characteristic of the different cell fate switches, which was predictive of the cancer cell of origin, tumour type and clinical outcomes in women with breast cancers.

Approximately one year after successful treatment with cytotoxic chemotherapy and radiotherapy, patients with advanced Small Cell Lung Cancer (SCLC), which primarily affects heavy smokers, generally relapse with recurrence of tumours that are resistant to further chemotherapy.

But as inflammation is known to promote the growth of cancer, they assumed that the cells were helping the tumours to grow.

RARE but pernicious cancer «stem» cells, blamed for the spread and invincibility of some tumours, may be more vulnerable than we thought.

Only cancer cells that received these growth factors switched on this pathway, and only they could seed new tumours when injected into mice.

The main reason why people die of cancer is that the cancer cells spread to form daughter tumours, or metastases, in vital organs, such as the lungs and liver.

He suggests, instead, that the team take T cells from the site of the tumour, because they would already be specialized for attacking cancer.

The team found that exposing samples of human glioblastoma tumours grown in a dish to the Zika virus destroyed the cancer stem cells.

Cancer stem - like cells are thought to be the root cause of chemotherapy resistance, leading to treatment failure in patients with advanced disease and the triggers of tumour recurrence and metastasis (regrowth).

A «Trojan horse» treatment for an aggressive form of brain cancer, which involves using tiny nanoparticles of gold to kill tumour cells, has been successfully tested by scientists.

Tumours grow through a process of Darwinian evolution, where cancer cells develop an advantageous mutation that allows them to survive and multiply, producing a population of cells which can mutate further.

The Lund University research team has looked at how cancer cells communicate with surrounding cells and how this encourages the development of malignant tumours.

The importance of exosomes in the tumour microenvironment has been demonstrated within the field in recent years, as it has been shown that tumour development is halted if the production of exosomes inside the cancer cell is stopped.

Cardiff University scientists have developed a novel anti-cancer stem cell agent capable of targeting aggressive tumour forming cells common to breast, pancreas, colon and prostate cancers.

A DEVICE that filters cancer cells from human blood using sound could help to identify tumour cells that have spread.

Around 15 per cent of women with breast cancer have this form of the disease, in which tumour cells lack the three receptors that most drugs target.

Within that sting lies a peptide called chlorotoxin, which has an unusual property — it sticks strongly to tumour cells while ignoring surrounding healthy tissue, by binding to a cancer - specific protein called matrix metalloproteinase - 2.

The researchers hope that ultimately human trials will prove the efficacy of the OH14 compound in sensitising tumour cells and cancer stem cells to existing drug - based therapies thus disabling tumours from seeding new growth after treatment.

This means that the cancer cells are no longer able to communicate as effectively and the tumour does not grow as it otherwise would.

Assessing just three features of a common kind of testicular cancer — called non-seminomatous germ cell tumour — can identify those at most at risk of relapse even where there is no evidence of tumour spread.

«Pancreatic cancer is extremely hard to treat by chemotherapy, so this finding is important because vitamin A targets the non-cancerous tissue and makes the existing chemotherapy more effective, killing the cancer cells and shrinking tumours.

A COMPOUND that slows the proliferation of triple - negative breast cancer cells in lab tests could lead to the first drugs to target this aggressive type of tumour.

Most researchers assumed that this is because a few rogue cancer cells find ways to circumvent the drugs before the whole tumour has been killed off.

Batimastat does not work this way: instead, it is designed to keep cancers in check by preventing malignant cells breaking away and forming secondary tumours elsewhere in the body.

In research funded by Sparks charity, Great Ormond Street Hospital Children's Charity and Cancer Research UK, researchers at the University of Cambridge have developed a test for blood and cerebrospinal fluid samples that looks for a specific panel of four pieces of short genetic code known as microRNAs, which are found in greater quantities in malignant germ cell tumours.

The time needed for breast cancer metastases (secondary lesions caused by cells that have escaped from the original tumour) to develop varies between patients, and little is known about the mechanisms that govern latency (the dormant state of cells that have already spread through the body).

When The Cancer Genome Atlas Research Network reported its genomic profiling of clear - cell kidney tumours, about one - quarter of participants (126 patients) had been operated on at Memorial Sloan Kettering3.

Most solid cancer tumours that have outgrown their blood supply, and are therefore deprived of oxygen, are difficult to treat, and the cells within are capable of spreading rapidly and doing the most damage.

Around 70 % of all cases of breast cancer are oestrogen - receptor positive, meaning that the cancer cells have a particular protein (known as a receptor) that responds to the female sex hormone oestrogen, enabling the tumour to grow.

Lead author Moustafa Abdalla writes: «Almost all genomic studies of breast cancer have focused on well - established tumours because it is technically challenging to study the earliest mutational events occurring in human breast epithelial cells.»

In addition, they showed for the first time that these genes are often the same as those that are altered in breast tumours - when a tumour develops, the DNA within the cancer cells themselves mutates.

Cancer stem cells are strongly associated with the growth and recurrence of all cancers and are especially difficult to eradicate with normal treatment, which also leads to tumours developing resistance to other types of therapy.

«We culture our cancer cells in this very low - oxygen environment, and they start behaving like they are inside a low - oxygen tumour.»

They placed the human cancer cells into the incubator and lowered the oxygen to a level comparable to that in a tumour.

Breast cancer researchers have mapped early genetic alterations in normal - looking cells at various distances from primary tumours to show how changes along the lining of mammary ducts can lead to disease.

The team used five types of antibiotics — including one used to treat acne (doxycycline)-- on cell lines of eight different types of tumour and found that four of them eradicated the cancer stem cells in every test.

Patients with TILs do much better because they already have cancer - fighting cells in their tumours.