Today his company is developing a new
cancer vaccine technology that teaches immune cells how to recognize and remove tumor cells.
Not exact matches
This
technology could help researchers rapidly generate new peptide drugs to test on a variety of diseases, and it also raises the possibility of easily producing customized
cancer vaccines for individual patients.
The 4 - year - old institute consists of six core research areas focused on a wide range of
technologies, from
cancer vaccines to robotic bees that will pollinate plants.
«This is an important demonstration of the possibilities opened up for immunotherapy by DMAb
technology to direct in vivo production of antibodies of major relevance to human
cancer,» said David B. Weiner, Ph.D., executive vice president of The Wistar Institute, director of The Wistar Institute Vaccine & Immunotherapy Center, W.W. Smith Charitable Trust Professor in Cancer Research, and senior author of the
cancer,» said David B. Weiner, Ph.D., executive vice president of The Wistar Institute, director of The Wistar Institute
Vaccine & Immunotherapy Center, W.W. Smith Charitable Trust Professor in
Cancer Research, and senior author of the
Cancer Research, and senior author of the study.
Cancer Vaccine Collaborative researchers Danila Valmori, Maha Ayyoub, Immanuel Luescher, and colleagues develop the first tetramer technology to monitor CD4 T cell responses to cancer vaccin
Cancer Vaccine Collaborative researchers Danila Valmori, Maha Ayyoub, Immanuel Luescher, and colleagues develop the first tetramer
technology to monitor CD4 T cell responses to
cancer vaccin
cancer vaccination.
Those selected for funding range from an antibacterial coating for orthopedic implants to a novel nano -
vaccine technology to a potential next - generation
cancer therapeutic.
Important reports from the Weiner lab include the first DNA
vaccine studied for HIV as well as for
cancer immune therapy of cutaneous T cell lymphoma, the early development of DNA encoded genetic adjuvants, including IL - 12, advances in gene optimization, and advances in electroporation
technologies resulting in improved gene delivery.
An international team led by researchers at the Broad Institute of MIT and Harvard, the Harvard T.H. Chan School of Public Health and Fred Hutchinson
Cancer Research Center uncovered the influence of genetic variation on
vaccine effectiveness after applying cutting - edge DNA sequencing
technology to almost 5,000 patient blood samples.
Wistar discoveries have led to the development of
vaccines for rabies, rubella, and rotavirus, the identification of genes associated with different types of
cancer, the development of monoclonal antibodies, and other significant research
technologies and tools.
Grant Title: 01787: Clinical advancement of RNA - transfected CD40 - B cell
vaccine technology for
cancer therapy