Sentences with phrase «cancerous changes in cells»

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Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human cell types, including normal and cancerous colon, lung and liver cells, as well as brain, skin, blood and embryonic stem cells.

The new device uses light scattering spectroscopy (LSS) to detect the structural changes that occur in cancerous or pre-cancerous cells by bouncing light off tissues and analyzing the reflected spectrum.

New experiments by UC Berkeley and UCSF researchers suggest that immortalization of skin cells, which is essential to turning them cancerous, is a two - step process: a mutation in nevus cells slightly raises levels of telomerase, which keep the cells alive long enough for a second change, still unknown, that up - regulates telomerase to make the cells immortal and malignant.

First author Adam Skibinski, M.D. / Ph.D., student at Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts University, said «We've known for a long time that breast cells can lose their normal identity when they become cancerous, but we are now realizing that normal cells can change their characteristics as well in response to transcription factors like TAZ.

«The cancerous cells need to change their behaviour, changing what proteins they synthesize in order to try to adapt to these environments.»

«Deoxygenation might even wipe out cancerous cells or pathogenic bacteria since they are very sensitive to changes in living environment pH. Of course, this is hypothetical right now, but we hope to investigate further with biologists and medical scientists.»

Previously scientists had to rely on cancerous cell lines to carry out such research, but the mutated genomes of these cells obscure early changes, which can be observed in still healthy cells.

In last week's Proceedings of the National Academy of Sciences, the researchers suggest that when the enzyme is knocked out the prostate cells may be more prone to cancerous changes.

Assistant Professor Camila dos Santos of Cold Spring Harbor Laboratory (CSHL) is studying stem cells in the breast for clues about what changes occur when normal breast cells become cancerous.

The team found that most of the late - passage cell batches, which were up to 3 years older than the early versions, showed genetic and methylation changes, some of which resemble those seen in cancerous cells.

Predicting Pancreatic Cancer Johns Hopkins researchers designed a computer program that can predict which changes in the DNA code may cause pancreatic cells to become cancerous and deadly.

The team is also studying changes in the tumor microenvironment — the cells that support cancerous cells in a tumor — to see if there are changes and the environment is more or less «inhabitable» following treatment.

Progressive darkening of the skin may also occur as a result of skin cancer, Cancerous cells which increase in number are associated with a change in skin pigment.