Sentences with phrase «candidate genes affecting»

Our goal is to find candidate genes affecting primary hypertension.

Not exact matches

McCallion's strategy to make sense of all this data looks at the active genes in cells affected by a disease, groups of genes that interact with one another, their vulnerability to mutation and information from past scientific studies to filter more than a thousand gene candidates for disease risk down to just a handful within any one implicated region.

Case studies described in the article show how microRNAs may affect voluntary alcohol consumption in mice, candidate genes within signaling pathways associated with chronic obstructive pulmonary disease, and the microRNA: gene interactions that influence bladder cancer.

They found that the associated regions contained numerous candidate genes, among them genes known to affect ear function, language development, memory, bird song and the brain's reward mechanism.

Cystic fibrosis may not be the most likely candidate for gene therapy, however, because the disease affects multiple organ systems.

The canine disease is compared to similar diseases in other species, most often humans, to determine if there are any possible candidate genes (i.e., genes that are known to be involved in these similar diseases or in the normal processes affected by the disease may offer important leads).

In order to perform candidate gene screening, we collected blood samples from normal and affected Swedish vallhund dogs.

The fact that the affected dogs do not share common alleles in any loci and same alleles were present in both cases and controls excludes these known PRA genes as candidates.

AGTC's lead product candidates focus on rare diseases of the eye, caused by mutations in single genes, that significantly affect visual function and currently lack effective medical treatments.