Sentences with phrase «candidate therapeutic targets»

Not exact matches

«SiteOne's therapeutic candidates exhibit impressive potency and selectivity for NaV1.7, and engage the target in a way that differentiates them from other inhibitors of Nav1.7.

The result is a new dual - targeting drug candidate — or, as Griffin describes, «one drug addressing multiple therapeutic indications» — that could treat both diabetes and bone disease.

Drugs that target KORs have shown promise as therapeutic candidates because of their efficacy for treating chronic itch and relieving pain.

Dr. Kirino says that «further studies to understand how SHOT - RNAs promote cell proliferation may lead to the use of SHOT - RNAs as potential target candidates for future therapeutic applications in breast and prostate cancers.»

Non-exclusive licenses are available for research and sale of products and services across multiple fields including: research tools, kits, reagents; discovery of novel targets for therapeutic intervention; cell lines for discovery and screening of novel drug candidates; GMP production of healthcare products; production of industrial materials such as enzymes, biofuels and chemicals; and synthetic biology.

This can help identify new molecules likely to inhibit certain therapeutic targets and to lead to novel drug candidates.

Cancer research in the era of genome medicine necessitates an in - depth understanding of protein functions before they can be explored as therapeutic targets or diagnostic candidates.

I look for genes, pathways, and candidate mutations associated with a disease, in order to understand the mechanism and the etiology of a disease, which may eventually lead to new therapeutic targets.

Carmot is applying an innovative technology, Chemotype Evolution, to overcome the limitations of conventional discovery technologies and identify superior drug candidates for challenging therapeutic targets.

Carmot is applying a transformative technology, Chemotype Evolution, to overcome the limitations of conventional discovery technologies and to identify superior drug candidates for challenging therapeutic targets.

Collagen Antibody Induced Arthritis (CAIA) is a simple mouse model of rheumatoid arthritis that can be used for the fast preclinical efficacy evaluation of candidate therapeutic agents targeting pathogenic mechanisms and inflammatory processes of arthritis.

Given DAXX's putative regulatory role in autophagy, future studies may consider DAXX as a candidate marker and therapeutic target for prostate cancer.

Translational medicine is the integrated application of innovative pharmacology tools, biomarkers, clinical methods, clinical technologies and study designs to improve disease understanding, confidence in human drug targets and increase confidence in drug candidates, understand the therapeutic index in humans, enhance cost - effective decision making in exploratory development and increase phase II success.

Many of these candidate modulators are novel to HD biology, giving hope that they will be able to soon elucidate a new class of HD therapeutic targets.

Their pipeline includes therapeutic candidates targeting pain, inappetence, cancer, viral diseases, allergy, and other serious, unmet or underserved medical needs.