Sentences with phrase «candidate tumor suppressor»

9) Thu KL, Radulovich N, Becker - Santos DD, Pikor LA, Pusic A, Lockwood WW, Lam WL, Tsao MS. SOX15 is a candidate tumor suppressor in pancreatic cancer with a potential role in Wnt / β - catenin signaling.

In conclusion, our study characterizes the biological function of DDX3 as a putative candidate tumor suppressor gene, at least in HCC and cutaneous SCC.

Because DDX3 exhibits tumor suppressor functions, such as a growth - suppressive property and transcriptional activation of the p21waf1 / cip1 promoter, and is inactivated through down - regulation of gene expression or alteration of subcellular localization in tumor cells, all these features together suggest that DDX3 might be a candidate tumor suppressor.

Not exact matches

«We knew ZMYND11 was a candidate tumor - suppressor because it's down - regulated in a number of human cancers, including breast cancer,» Shi said.

Let's say that you've identified a new possible cancer susceptibility gene, a candidate tumor - suppressor.